This book provides readers with a collection of latest reviews
written by Chikungunya virus (CHIKV) research leaders who cover
topics related to CHIKV replication, advances in CHIKV research
reagents and model system development, as well as the pathogenesis
of chronic CHIKV disease. Moreover, the volume updates on recent
progress in the development of therapeutics and vaccines for
treatment and prevention of CHIKV-induced disease. Chikungunya
virus (CHIKV) is a mosquito-borne pathogen that has re-emerged to
become a significant global disease threat. Although CHIKV has
historically been associated with localized outbreaks of
debilitating polyarthralgia in Africa and Asia, factors such as
increased global travel and viral adaptation to new mosquito
vectors have led to the introduction and spread of CHIKV in new
regions of the world, including the Americas. The re-emergence of
CHIKV has stimulated significant interest both in understanding the
biology of CHIKV and in the development of medical countermeasures
against the virus.
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