|
Books > Science & Mathematics > Biology, life sciences > Molecular biology
|
Buy Now
Gene Knockout Protocols (Hardcover, 2001 ed.)
Loot Price: R3,202
Discovery Miles 32 020
|
|
|
Gene Knockout Protocols (Hardcover, 2001 ed.)
Series: Methods in Molecular Biology, 158
Expected to ship within 12 - 17 working days
|
As the major task of sequencing the human genome is near completion
and full complement of human genes are catalogued, attention will
be focused on the ultimate goal: to understand the normal
biological functions of these genes, and how alterations lead to
disease states. In this task there is a severe limitation in
working with human material, but the mouse has been adopted as the
favored animal model because of the available genetic resources and
the highly conserved gene conservation linkage organization. In
just of ten years since the first gene-targeting experiments were
p- formed in embryonic stem (ES) cells and mutations transmitted
through the mouse germline, more than a thousand mouse strains have
been created. These achievements have been made possible by
pioneering work that showed that ES cells derived from
preimplantation mouse embryos could be cultured for prolonged
periods without differentiation in culture, and that homologous
rec- bination between targeting constructs and endogenous DNA
occurred at a f- quency sufficient for recombinants to be isolated.
In the next few years the mouse genome will be systematically
altered, and the techniques for achi- ing manipulations are
constantly being streamlined and improved.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
You might also like..
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.
Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
