0
Your cart

Your cart is empty

Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology

Buy Now

The Scid Mouse - Characterization and Potential Uses (Paperback, Softcover reprint of the original 1st ed. 1989) Loot Price: R2,879
Discovery Miles 28 790
The Scid Mouse - Characterization and Potential Uses (Paperback, Softcover reprint of the original 1st ed. 1989): Melvin J....

The Scid Mouse - Characterization and Potential Uses (Paperback, Softcover reprint of the original 1st ed. 1989)

Melvin J. Bosma, Robert A. Phillips, Walter Schuler

Series: Current Topics in Microbiology and Immunology, 152

 (sign in to rate)
Loot Price R2,879 Discovery Miles 28 790 | Repayment Terms: R270 pm x 12*

Bookmark and Share

Expected to ship within 10 - 15 working days

During routine genetic screening of several immunoglobulin heavy chain congenic mouse strains in 1980, one of us (MB) was surprised to find that several mice in the C.B-17IIcr strain, which was being maintained in a specific-pathogen-free facility of the Fox Chase Cancer Center (Philadelphia, PA), did not express serum immunoglobulin of the appropriate allotype. Fearing an error in the breeding of these mice, the sera of the suspect mice were screened for other allotypes. When these tests revealed a complete absence of serum immunoglobulin, it became apparent that a mutation had probably occurred in the C.B-17IIcr line. Further analysis revealed that a single breeding pair was respon sible for all of the immunoglobulin negative mice and that the defect showed recessive inheritance. Thus was the C.B-17/Icr scid or severe combined immune deficient (scid) mouse discovered. Although it has taken most animal facilities several years to breed scid mice of high quality for experimental purpose, it was clear by 1987 that many investigators were beginning to exploit the unique qualities of the scid mouse for studies in several areas.

General

Imprint: Springer-Verlag
Country of origin: Germany
Series: Current Topics in Microbiology and Immunology, 152
Release date: December 2011
First published: 1989
Editors: Melvin J. Bosma • Robert A. Phillips • Walter Schuler
Dimensions: 242 x 170 x 15mm (L x W x T)
Format: Paperback
Pages: 263
Edition: Softcover reprint of the original 1st ed. 1989
ISBN-13: 978-3-642-74976-6
Categories: Books > Medicine > Nursing & ancillary services > Biomedical engineering > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > Allergies
Promotions
LSN: 3-642-74976-3
Barcode: 9783642749766

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!

You might also like..

Targeted Nanomedicine for Breast Cancer…
Shivani Rai Paliwal, Rishi Paliwal Paperback R4,773 Discovery Miles 47 730
Encyclopedia of Infection and Immunity
Nima Rezaei Hardcover R62,178 Discovery Miles 621 780
Immunotherapy in Resistant Cancer: From…
Jorge Morales Montor, Mariana Segovia Hardcover R3,725 Discovery Miles 37 250
Sphingolipids in Cancer, Volume 140
Charles E. Chalfant, Paul B. Fisher Hardcover R3,977 Discovery Miles 39 770
Lung Cancer, An Issue of…
Roy S. Herbst, Daniel Morgensztern Hardcover R2,256 Discovery Miles 22 560
Adjunctive Rehabilitation Approaches to…
Andrea L. Cheville Hardcover R2,257 Discovery Miles 22 570
Pediatric Brain Tumors Update, An Issue…
Lara Brandao Hardcover R2,274 Discovery Miles 22 740
Neuroendocrine Tumors, An Issue of…
Jennifer Chan, Matthew Kulke Hardcover R1,799 Discovery Miles 17 990
Geriatric Oncology, An Issue of Clinics…
Harvey J. Cohen, Arati V Rao Hardcover R1,796 Discovery Miles 17 960
Pulmonary Metastasectomy, An Issue of…
Mark W Onaitis, Thomas A. D'Amico Hardcover R2,658 Discovery Miles 26 580
Testicular Cancer, An Issue of Urologic…
Daniel W. Lin Hardcover R1,800 Discovery Miles 18 000
Bladder Cancer, An Issue of…
Joaquim Bellmunt Hardcover R1,795 Discovery Miles 17 950

See more

Partners