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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Systems Biology (Hardcover, 2013 ed.)
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Systems Biology (Hardcover, 2013 ed.)
Series: Current Topics in Microbiology and Immunology, 363
Expected to ship within 12 - 17 working days
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In this volume, a wide-ranging series of reviews reveal how systems
biology -- a holistic and inter-disciplinary approach requiring the
combined talents of biologists, mathematicians, and computer
scientists -- is changing the face of infectious disease research.
Leading experts discuss how the use of high-throughput and
computational approaches are generating exciting -- and often
unexpected -- new insights into the microbial-host interactions of
a variety of bacterial and viral pathogens, including Salmonella,
Yersinia, Mycobacterium, influenza virus, human and simian
immunodeficiency virus, and hepatitis C virus. Additional chapters
focus on systems approaches to innate immunity, intra- and inter-
cellular signaling, biomarker discovery, and the evaluation and
rational development of improved vaccines. Systems biology has both
been hailed as a paradigm shift that will revolutionize biological
science and criticized as overly expensive and complex. While the
truth no doubt lies somewhere in between, the approach is yielding
increasingly detailed and comprehensive views of biological systems
and processes, including those that dictate the host response to
infection and disease outcome. Systems Biology of Infectious
Disease is highly informative reading for investigators already
engaged in systems biology research as well as for those scientists
and clinicians who may be seeking an introduction to the field.
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