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Structured Biological Modelling - A New Approach to Biophysical Cell Biology (Hardcover)
Loot Price: R10,619
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Structured Biological Modelling - A New Approach to Biophysical Cell Biology (Hardcover)
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Structured Biological Modelling presents a straightforward
introduction for computer-aided analysis, mathematical modelling,
and simulation of cell biological systems. This unique guide brings
together the physiological, structural, molecular biological, and
theoretical aspects of the signal transduction network that
regulates growth and proliferation in normal and tumor cells. It
provides comprehensive survey of functional and theoretical
features of intracellular signal processing and introduces the
concept of cellular self-organization. Exemplified by oscillatory
calcium waves, strategies for the design of computer experiments
are presented that can assist or even substitute for time-consuming
biological experiments. The presented minimal model for
proliferation-associated signal transduction clearly shows the
alterations of the cellular signal network involved in neoplastic
growth. This book will be useful to cell and molecular biologists,
oncologists, physiologists, theoretical biologists, computer
scientists, and all other researchers and students studying
functional aspects of cellular signaling.
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