Neuropsychiatric disorders such as schizophrenia, mood
disorders, Alzheimer s disease, epilepsy, alcoholism, substance
abuse and others are one of the most debilitating illnesses
worldwide characterizing by the complexity of the causes, and
lacking the laboratory tests that may promote diagnostic and
prognostic procedures. Recent advances in neuroscience, genomic,
genetic, proteomic and metabolomic knowledge and technologies have
opened the way to searching biomarkers and endophenotypes, which
may offer powerful and exciting opportunity to understand the
etiology and the underlying pathophysiological mechanisms of
neuropsychiatric disorders. The challenge now is to translate these
advances into meaningful diagnostic and therapeutic advances. This
book offers a broad synthesis of the current knowledge about
diverse topics of the biomarker and endophenotype strategies in
neuropsychiatry.
The book is organized into four interconnected volumes:
Neuropsychological Endophenotypes and Biomarkers (with overview of
methodological issues of the biomarker and endophenotype approaches
in neuropsychiatry and some technological advances),
Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers,
Metabolic and Peripheral Biomarkers and Molecular Genetic and
Genomic Markers . The contributors are internationally and
nationally recognized researchers and experts from 16 countries.
This four-volume handbook is intended for a broad spectrum of
readers including neuroscientists, psychiatrists, neurologists,
endocrinologists, pharmacologists, clinical psychologists, general
practitioners, geriatricians, health care providers in the field of
neurology and mental health interested in trends that have
crystallized in the last decade, and trends that can be expected to
further evolve in the coming years. It is hoped that this book will
also be a useful resource for the teaching of psychiatry,
neurology, psychology and mental health. "
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