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Peptide Synthesis Protocols (Paperback, 1995 ed.)
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Peptide Synthesis Protocols (Paperback, 1995 ed.)
Series: Methods in Molecular Biology, 35
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Peptide synthesis has emerged as one of the most powerful tools in
biochemical, pharmacological, immunological, and biophysical la-
ratories. Recent improvements include general solid-phase method-
ogy, new protecting groups, and automated equipment. These advances
have allowed the facile synthesis of increasingly more complex p-
tides. Many of these new and improved methods for the synthesis of
peptides and peptide-related substances have been reported in
various publications, but never compiled in a convenient handbook.
Like other volumes in this series, Peptide Synthesis Protocols
concentrates on the practical aspects of these procedures,
providing the researcher with detailed descriptions and helpful
tips about potential problems. This volume is not intended to serve
as a basic guide to standard Merrifie- type solid-phase strategy,
but rather to provide the researcher with some of the most recent
applications in the field of peptide science. A c- panion volume,
Peptide Analysis Protocols, will detail methodology for the
charaterization of new synthetic peptides. Development of new
methods and applications has continued actively even as this volume
was in preparation. Owing to the number of contributors to this
volume, it was necessary to establish a cutoff for publication
purposes. We feel that all of the protocols presented are timely
and up-to-date. Several promising new strategies, such as
allyloxycarbonyl-based syntheses, were being developed at the time
this volume was in the editing stages and will be included in
future editions.
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