Recent studies have shown that cells from adipose tissue are
capable of trafficking to tumors, thus enabling paracrine action of
adipokines from within the tumor microenvironment. Increased tumor
vascularization, immune system suppression and direct effects on
malignant cell survival and proliferation have been investigated as
mechanisms regulated by adipokines. The goal of this book is to
discuss data pointing to the role of adipose tissue in cancer and
to dissect individual mechanisms through which adipose tissue
excess or restriction could influence cancer progression.
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