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Recognition Receptors in Biosensors (Paperback, Softcover reprint of the original 1st ed. 2010)
Loot Price: R5,748
Discovery Miles 57 480
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Recognition Receptors in Biosensors (Paperback, Softcover reprint of the original 1st ed. 2010)
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Recognition receptors play a key role in the successful
implementation of chemical and biosensors. Molecular recognition
refers to non-covalent speci?c binding between molecules, one of
which is typically a macromolecule or a molecular assembly, and the
other is the target molecule (ligand or analyte). Biomolecular
recognition is typically driven by many weak interactions such as
hydrogen bo- ing, metal coordination, hydrophobic forces, van der
Waals forces, pi-pi interactions and electrostatic interaction (due
to permanent charges, dipoles, and quadrupoles) the polarization of
charge distributions by the interaction partner leading to ind-
tion and dispersion forces, and Pauli-exclusion-principle-derived
inter-atomic repulsion, and a strong, "attractive" force arising
largely from the entropy of the solvent and termed the hydrophobic
effect. In recent years, there has been much progress in
understanding the forces that drive the formation of such
complexes, and how these forces are relate to the physical
properties of the interacting molecules and their environment
allows rational design of molecules and materials that interact in
speci?c and desired ways. This book presents a signi?cant and
up-to-date review of the various recognition elements, their
immobilization, characterization techniques by a panel of dist-
guished scientists. This work is a comprehensive approach to the
recognition receptors area presenting a thorough knowledge of the
subject and an effective integration of these receptors on sensor
surfaces in order to appropriately convey the state-of the-art
fundamentals and applications of the most innovative approaches.
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