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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Stem Cell Biology in Neoplasms of the Central Nervous System (Hardcover, 2015 ed.)
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Stem Cell Biology in Neoplasms of the Central Nervous System (Hardcover, 2015 ed.)
Series: Advances in Experimental Medicine and Biology, 853
Expected to ship within 12 - 17 working days
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This volume presents the most current reviews on how cancer stem
cells (CSCs) hypothesis dictates that the continued proliferation
of a tumor is dependent on a sub-population of self-renewing and
asymmetrically dividing neoplastic stem cells that supply a largely
differentiated tumor. This volume provides a comprehensive overview
of the characteristics of CSCs, their role in central nervous
system (CNS) tumors, and the recent CSC-specific treatment
modalities being used. The emerging focus on CSCs in brain tumors
represents a paradigm shift in our understanding of the
pathogenesis of these neoplasms. Importantly, the realization that
a distinct sub-population of cells contributes disproportionately
to the growth and sustenance of central nervous system tumors has
important implications for the treatment of such tumors. To treat
CNS tumors, there is now a growing need to treat CSCs to achieve
adequate tumor control.
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