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Plant and Human Health, Volume 2 - Phytochemistry and Molecular Aspects (Hardcover, 1st ed. 2019)
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Plant and Human Health, Volume 2 - Phytochemistry and Molecular Aspects (Hardcover, 1st ed. 2019)
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Early anthropological evidence for plant use as medicine is 60,000
years old as reported from the Neanderthal grave in Iraq. The
importance of plants as medicine is further supported by
archeological evidence from Asia and the Middle East. Today, around
1.4 billion people in South Asia alone have no access to modern
health care, and rely instead on traditional medicine to alleviate
various symptoms. On a global basis, approximately 50 to 80
thousand plant species are used either natively or as
pharmaceutical derivatives for life-threatening conditions that
include diabetes, hypertension and cancers. As the demand for
plant-based medicine rises, there is an unmet need to investigate
the quality, safety and efficacy of these herbals by the
"scientific methods". Current research on drug discovery from
medicinal plants involves a multifaceted approach combining
botanical, phytochemical, analytical, and molecular techniques. For
instance, high throughput robotic screens have been developed by
industry; it is now possible to carry out 50,000 tests per day in
the search for compounds which act on a key enzyme or a subset of
receptors. This and other bioassays thus offer hope that one may
eventually identify compounds for treating a variety of diseases or
conditions. However, drug development from natural products is not
without its problems. Frequent challenges encountered include the
procurement of raw materials, the selection and implementation of
appropriate high-throughput bioassays, and the scaling-up of
preparative procedures. Research scientists should therefore arm
themselves with the right tools and knowledge in order to harness
the vast potentials of plant-based therapeutics. The main objective
of Plant and Human Health is to serve as a comprehensive guide for
this endeavor. Volume 1 highlights how humans from specific areas
or cultures use indigenous plants. Despite technological
developments, herbal drugs still occupy a preferential place in a
majority of the population in the third world and have slowly taken
roots as alternative medicine in the West. The integration of
modern science with traditional uses of herbal drugs is important
for our understanding of this ethnobotanical relationship. Volume 2
deals with the phytochemical and molecular characterization of
herbal medicine. Specifically, It will focus on the secondary
metabolic compounds which afford protection against diseases.
Lastly, Volume 3 focuses on the physiological mechanisms by which
the active ingredients of medicinal plants serve to improve human
health. Together this three-volume collection intends to bridge the
gap for herbalists, traditional and modern medical practitioners,
and students and researchers in botany and horticulture.
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