Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases (Hardcover, 2015 ed.)

This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed 'amyloid'. Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer's disease-related dementia and Parkinson's disease, as well as other less prevalent conditions like Huntington's disease, cerebral amyloid angiopathy and the transmissible prion disorders. A disease-modifying therapeutic agent is still lacking for all these diseases, and there are no approved therapies that target amyloid formation directly. Nevertheless, a large and complex group of natural aromatic compounds known as polyphenols are rapidly emerging as potentially potent anti-amyloidogenic agents. This book collectively presents a considerable body of experimental and epidemiological evidence from peer-reviewed scientific publications that support a role for natural compounds and herbal extracts in the chemoprevention and therapy of amyloidogenic disorders. Each contribution is written by scientific experts in the relevant field; chapters are devoted to Mediterranean diet and olive oil phenols, traditional Chinese medicine, herbal extracts, polyphenols (with a particular emphasis on epigallocatechin-3-gallate) and bi-flavonoids, amongst others. The topic of this book is relevant to a wide audience, from academia and university students in the biological and chemical sciences, to physicians and allied health professionals, as well as people working in the nutraceutical industry.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Series:	Advances in Experimental Medicine and Biology, 863
Release date:	July 2015
First published:	2015
Editors:	Neville Vassallo
Dimensions:	254 x 178 x 11mm (L x W x T)
Format:	Hardcover - Cloth over boards
Pages:	163
Edition:	2015 ed.
ISBN-13:	978-3-319-18364-0
Categories:	Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology Books > Medicine > Nursing & ancillary services > Pharmacy / dispensing Books > Medicine > General issues > Public health & preventive medicine > Epidemiology & medical statistics Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
LSN:	3-319-18364-8
Barcode:	9783319183640

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