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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Capillary Electrophoresis of Carbohydrates - From Monosaccharides to Complex Polysaccharides (Hardcover, Edition.)
Loot Price: R4,256
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Capillary Electrophoresis of Carbohydrates - From Monosaccharides to Complex Polysaccharides (Hardcover, Edition.)
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Simple carbohydrates, complex oligosaccharides and polysaccharides
all belong to a class of ubiquitous (macro)molecules that exhibit a
wide range of biological functions, and the recent advent of
enhanced enzymatic, chemical and analytical tools used to study
these sugars has inaugurated a genuine explosion in the field of
glycomics. Specifically, it has led to a deeper understanding of
how specific sugar structures modulate cellular phenotypes, and
that breakthrough has led to the discovery of new pharmaceuticals
for the treatment of many serious diseases, such as cancer. The
subsequent rapid expansion of this research holds high promise for
future therapeutic regimens, and capillary electrophoresis (CE)
refers to the range of related separation techniques that are
integral to this vital research. CE uses narrow-bore fused-silica
capillaries to separate a complex array of large and small
molecules, and Capillary Electrophoresis of Carbohydrates offers a
comprehensive look at the latest breakthroughs and improvements in
CE and CE techniques applied to monosaccharides up to complex
oligosaccharides and polysaccharides. It begins with an overview of
the application of CE and CE- mass spectrometric in the analysis of
simple carbohydrates without any previous derivatization step
before discussing various detection techniques such as
spectrophotometric detection, electrochemical detection and other
less common techniques. It then covers in detail an array of
related topics and numerous applications. It is an essential text
for anyone exploring the myriad possibilities of this rapidly
expanding field.
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