Capillary electrophoresis (CE) comprises a family of related
separation techniques in which an electric field is used to achieve
the separation of components in a mixture. One of the key features
of CE is the simplicity of the instrumentation required, and today,
these techniques have become powerful analytical tools for high
efficiency separation, and the identification of a variety of ionic
and neutral compounds. Moreover, the versatility of CE operational
modes (capillary zone electrophoresis, micellar electrokinetic
capillary chromatography, capillary electrochromatography,
capillary isoelectric focusing, isotachophoresis, non-aqueous
capillary electrophoresis, etc.) and detection systems
(ultraviolet, fluorescence, amperometric, mass spectrometrya|) make
CE useful for applications in many fields such as environmental,
food, pharmaceutical, and forensic analysis. The typcial drawback
of CE techniques, based on their low sensitivity when dealing with
conventional UV-detection, due to their short detection pathways
and the short sample volume introduced into the capillary, has been
largely resolved not only by using more sensitive detectors like
fluorescence, amperometric, or mass spectrometry, but by the
employment of both off-line and on-line enrichment procedures. The
aim of this present book is to address the state-of-the art of
capillary electrophoresis techniques within this early twenty-first
century, by reviewing new trends and the most relevant applications
described in the literature. Uses in fields such as food,
environmental, forensic and biological analysis are addressed by
means of relevant application. The scope of this book is
intentionally broad and is aimed at worldwide analytical
laboratories, both public and private, at acadamic institutions, as
well as researchers.
General
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