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Books > Science & Mathematics > Biology, life sciences > Biochemistry
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DNA Methods in Clinical Microbiology (Paperback, Softcover reprint of hardcover 1st ed. 2000)
Loot Price: R4,011
Discovery Miles 40 110
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DNA Methods in Clinical Microbiology (Paperback, Softcover reprint of hardcover 1st ed. 2000)
Expected to ship within 18 - 22 working days
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DNA Methods in Clinical Microbiology describes the novel DNA-based
technology now used in the diagnosis and management of infectious
diseases. It is a concise, yet readable, overview written primarily
for clinicians, clinical microbiologists, medical students and
undergraduates in medical and veterinary microbiology. The book has
two primary aims. First, to explain the principles of these methods
at the molecular' level. Second, to provide a clinical perspective
by reporting results from actual DNA-based investigations on a
range of specimens. Those approaching DNA methods for the first
time are assisted by a brief resume of the relevant features of
nucleic acids (Chapter 2): this information is essential for an
understanding of later chapters. Subsequent text covers detection,
characterization and quantification of pathogens by a variety of
methods - e.g., target amplification (PCR, LCR, NASBA, TMA and
SDA), signal amplification (bDNA) and probe-based techniques; the
chapter on typing describes nearly twenty named molecular methods,
including spoligotyping and MLST. All chapters include an adequate
range of current reference from which, if required, detailed
protocols can be obtained. The diagrams are clear, and readers are
assisted by a detailed index."
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