Non-Invasive Monitoring of Transdermal Drug Delivery (Hardcover)

The book presents an innovative technology based on injection of a very weak current to trace the quantity of a drug carried immediately after the administration. The book makes the reader familiar with the technology, from the conception through the design of the instrument, up to the preliminary clinical applications. In the first chapter, the method of transdermal drug delivery and the use of impedance spectroscopy in the dermatological field are presented. The second chapter describes a screening measurement campaign aimed at proving the feasibility of the assessment method and identifying the bandwidth of interest. The prototyping, validation and characterization of an instrument to measure the amount of drug delivered (DUSM: Drug Under Skin Meter) are presented in chapter three. In the fourth chapter three experimental campaigns, based on the electrical analysis of the biological tissue behavior due to the drug delivery, are reported: (i) laboratory emulation on eggplants, (ii) ex-vivo tests on pig ears, and finally (iii) in-vivo tests on human volunteers. In the fifth chapter a behavioral model, based on Finite Elements and Partial Differential Equation, of an impedance-based measurement system for assessing the drug released under the skin, during transdermal delivering, is proposed. The last chapter is dedicated to present a campaign in order to prove the suitability for insulin therapy applications. This book is intended for biomedical engineers, biomedical engineering students, operators working in the field of biomedical instrumentation, biotechnologists, and technicians of transdermal vehiculation.

General

Imprint:	Crc Press
Country of origin:	United Kingdom
Release date:	March 2022
First published:	2022
Authors:	Pasquale Arpaia • Umberto Cesaro • Nicola Moccaldi • Isabella Sannino
Dimensions:	234 x 156mm (L x W)
Format:	Hardcover
Pages:	174
ISBN-13:	978-0-367-76598-9
Categories:	Books > Science & Mathematics > Biology, life sciences > General Books > Professional & Technical > Environmental engineering & technology > General Books > Medicine > Other branches of medicine > Pharmacology > General Books > Medicine > Nursing & ancillary services > Biomedical engineering > General Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology Promotions
LSN:	0-367-76598-5
Barcode:	9780367765989

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