Books > Medicine > Nursing & ancillary services > Biomedical engineering
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Non-Invasive Monitoring of Transdermal Drug Delivery (Hardcover)
Loot Price: R4,140
Discovery Miles 41 400
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Non-Invasive Monitoring of Transdermal Drug Delivery (Hardcover)
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Donate to Against Period Poverty
Total price: R4,160
Discovery Miles: 41 600
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The book presents an innovative technology based on injection of a
very weak current to trace the quantity of a drug carried
immediately after the administration. The book makes the reader
familiar with the technology, from the conception through the
design of the instrument, up to the preliminary clinical
applications. In the first chapter, the method of transdermal drug
delivery and the use of impedance spectroscopy in the
dermatological field are presented. The second chapter describes a
screening measurement campaign aimed at proving the feasibility of
the assessment method and identifying the bandwidth of interest.
The prototyping, validation and characterization of an instrument
to measure the amount of drug delivered (DUSM: Drug Under Skin
Meter) are presented in chapter three. In the fourth chapter three
experimental campaigns, based on the electrical analysis of the
biological tissue behavior due to the drug delivery, are reported:
(i) laboratory emulation on eggplants, (ii) ex-vivo tests on pig
ears, and finally (iii) in-vivo tests on human volunteers. In the
fifth chapter a behavioral model, based on Finite Elements and
Partial Differential Equation, of an impedance-based measurement
system for assessing the drug released under the skin, during
transdermal delivering, is proposed. The last chapter is dedicated
to present a campaign in order to prove the suitability for insulin
therapy applications. This book is intended for biomedical
engineers, biomedical engineering students, operators working in
the field of biomedical instrumentation, biotechnologists, and
technicians of transdermal vehiculation.
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