Legionella pneumophila is an emerging human pathogen that
resides in natural environments as a parasite of freshwater. There
have been new developments in this field including the publication
of three whole genome sequences, the discovery of a developmental
cycle and novel cyst-like highly infectious form, and the bacteria
have been used as a probe for macrophage cellular function to
unravel fundamental new knowledge in the area of cellular biology.
Legionella has also become a model system for the study of innate
as well as adaptive immunity. Information on Legionella continues
to increase in the U.S. and abroad. Columbia University has started
the first Legionella Genome Project with a multi-million dollar
grant from the NIH. In addition, The European Working Group for
Legionella infections was formed in 1986. Members are scientists
with an interest in improving knowledge and information on the
clinical and environmental aspects of legionnaires' disease through
developments in diagnosis, management and treatment of the disease.
The volume brings together all of the lastest research on this
pathogen, the interest in which is rapidly growing.
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