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Evolving Concepts in Sepsis and Septic Shock (Paperback, Softcover reprint of the original 1st ed. 2001)
Loot Price: R4,415
Discovery Miles 44 150
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Evolving Concepts in Sepsis and Septic Shock (Paperback, Softcover reprint of the original 1st ed. 2001)
Series: Perspectives on Critical Care Infectious Diseases, 2
Expected to ship within 10 - 15 working days
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Much research over the past 30 to 40 years has shown that the
inflammatory response, while critical for host defense during
microbial infection, may itself play a central role in the
pathogenesis of sepsis. Although key mediators responsible for this
injury have been identified, efforts clinically to augment our
conventional antimicrobial and supportive therapies during sepsis
with agents modulating the inflammatory response have been
unsuccessful. As a result, the mortality associated with this
lethal syndrome, especially when complicated by shock, has remained
persistently high. Unfortunately, during this same period of time,
the incidence of sepsis has accelerated as other fields of medicine
have relied increasingly on therapies that predispose to infection.
While frustrating, overall this experience in the field of sepsis
has not been without value. Most importantly, it has helped define
on several different levels the complexity of the septic patient.
Recognizing and addressing this complexity as discussed by each of
the contributors to Evolving Concepts in Sepsis and Septic Shock
may now provide new inroads into the treatment of sepsis.
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