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Books > Professional & Technical > Biochemical engineering > Biotechnology
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The Minimal Cell - The Biophysics of Cell Compartment and the Origin of Cell Functionality (Paperback, 2011 ed.)
Loot Price: R4,232
Discovery Miles 42 320
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The Minimal Cell - The Biophysics of Cell Compartment and the Origin of Cell Functionality (Paperback, 2011 ed.)
Expected to ship within 10 - 15 working days
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In the last ten years there has been a considerable increase of
interest on the notion of the minimal cell. With this term we
usually mean a cell-like structure containing the minimal and
sufficient number of components to be defined as alive, or at least
capable of displaying some of the fundamental functions of a living
cell. In fact, when we look at extant living cells we realize that
thousands of molecules are organized spatially and functionally in
order to realize what we call cellular life. This fact elicits the
question whether such huge complexity is a necessary condition for
life, or a simpler molecular system can also be defined as alive.
Obviously, the concept of minimal cell encompasses entire families
of cells, from totally synthetic cells, to semi-synthetic ones, to
primitive cell models, to simple biomimetic cellular systems.
Typically, in the experimental approach to the construction of
minimal the main ingredient is the compartment. Lipid vesicles
(liposomes) are used to host simple and complex molecular
transformations, from single or multiple enzymic reactions, to
polymerase chain reactions, to gene expression. Today this research
is seen as part of the broader scenario of synthetic biology but it
is rooted in origins of life studies, because the construction of a
minimal cell might provide biophysical insights into the origins of
primitive cells, and the emergence of life on earth. The volume
provides an overview of physical, biochemical and functional
studies on minimal cells, with emphasis to experimental approaches.
15 International experts report on their innovative contributions
to the construction of minimal cells.
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