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Modern Biophysical Chemistry - Detection and Analysis of Biomolecules 2e (Paperback, 2nd Edition)
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Modern Biophysical Chemistry - Detection and Analysis of Biomolecules 2e (Paperback, 2nd Edition)
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This updated and up-to-date version of the first edition continues
with the really interesting stuff to spice up a standard biophysics
and biophysical chemistry course. All relevant methods used in
current cutting edge research including such recent developments as
super-resolution microscopy and next-generation DNA sequencing
techniques, as well as industrial applications, are explained. The
text has been developed from a graduate course taught by the author
for several years, and by presenting a mix of basic theory and
real-life examples, he closes the gap between theory and
experiment. The first part, on basic biophysical chemistry, surveys
fundamental and spectroscopic techniques as well as biomolecular
properties that represent the modern standard and are also the
basis for the more sophisticated technologies discussed later in
the book. The second part covers the latest bioanalytical
techniques such as the mentioned super-resolution and next
generation sequencing methods, confocal fluorescence microscopy,
light sheet microscopy, two-photon microscopy and ultrafast
spectroscopy, single molecule optical, electrical and force
measurements, fluorescence correlation spectroscopy, optical
tweezers, quantum dots and DNA origami techniques. Both the text
and illustrations have been prepared in a clear and accessible
style, with extended and updated exercises (and their solutions)
accompanying each chapter. Readers with a basic understanding of
biochemistry and/or biophysics will quickly gain an overview of
cutting edge technology for the biophysical analysis of proteins,
nucleic acids and other biomolecules and their interactions.
Equally, any student contemplating a career in the chemical,
pharmaceutical or bio-industry will greatly benefit from the
technological knowledge presented. Questions of differing
complexity testing the reader's understanding can be found at the
end of each chapter with clearly described solutions available on
the Wiley-VCH textbook homepage under: www.wiley-vch.de/textbooks
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