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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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The Society of Cells - Cancer and Control of Cell Proliferation (Paperback)
Loot Price: R2,713
Discovery Miles 27 130
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The Society of Cells - Cancer and Control of Cell Proliferation (Paperback)
Expected to ship within 12 - 17 working days
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Donate to Against Period Poverty
Total price: R2,733
Discovery Miles: 27 330
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For more than 30 years, the majority of researchers has assumed
quiescence to be the default state of all cells and so have
provided cells in culture with 'growth factors' to stimulate them
to proliferate. During this time, many putative growth factors have
been identified and ever more complex mechanisms through which they
could interact and stimulate cells have been proposed. However,
quiescence as the default state does not make evolutionary sense
and many sets of data do not support this hypothesis. In The
Society of Cells, an alternative explanation for these results is
proposed by applying the premise that the default state must be
proliferation, with multiplication being a 'built in' property of
all forms of life. The authors begin by reviewing the concepts and
theories that guide research on the control of cell proliferation
and cancer, and asking the question 'what is the nature of the
default state of all cells - quiescence or proliferation?'. Later
chapters concern cancer, where control of cell proliferation and
the tissue organisation are defective. Despite decades of work and
financial support to explore the somatic mutation theory of
carcinogenesis, we appear no nearer to explaining how cancer
arises. This requires researchers to take stock and consider new
hypotheses and alternative approaches to the study of control of
cell proliferation, and cancer in particular. The Society of Cells
is intended to encourage such a revaluation and proposes the
adoption of new premises to explore these important subjects.
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