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Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics (Hardcover, 1st ed. 2018)
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Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics (Hardcover, 1st ed. 2018)
Series: Springer Theses
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This thesis documents the development of a multifunctional
nanoparticle system to enhance the chemotherapeutic efficiency of
anti-cancer drugs, and contributes to research that helps decrease
the side-effects in cancer patients while simultaneously increasing
their survival rates. The work begins with an introduction to
nanomedicine and cancer therapy, and contains a literature review
on magnetic, gold, and core-shell nanoparticles. It also covers
synthesis techniques, properties, various surface modifications,
and the importance of magnetic and gold nanoparticles. The author
dedicates a chapter to characterization techniques, experimental
setup, and cell cultivation techniques for in-vitro studies.
Further chapters describe the background, characterizations, and
applications of multifunctional magnetite coated gold core-shell
nanoparticles, and the doping of cobalt to magnetite and manganese
to magnetite nanoparticles. The important highlight of this
research was the control of the size, shape, composition, and
surface chemistry of nanoparticles.
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