Gene Expression and Its Discontents - The Social Production of Chronic Disease (Paperback, 2010 ed.)

Gene Expression and its Discontents examines a class of probability models describing how epigenetic context affects gene expression and organismal development, using the asymptotic limit theorems of information theory in a highly formal manner. Taking classic results on spontaneous symmetry breaking abducted from statistical physics in groupoid, rather than group, circumstances, the work suggests that epigenetic information sources act as analogs to a tunable catalyst, directing development into different characteristic pathways according to the structure of external signals. The results have significant implications for epigenetic epidemiology, in particular for understanding how environmental stressors, in a large sense, can induce a broad spectrum of developmental disorders in humans. The authors then apply the perspective to a number of chronic diseases broadly associated with obesity, using data at different scales of observation.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Release date:	November 2014
First published:	2010
Authors:	Rodrick Wallace • Deborah Wallace
Dimensions:	235 x 155 x 13mm (L x W x T)
Format:	Paperback
Pages:	227
Edition:	2010 ed.
ISBN-13:	978-1-4899-8531-6
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Medicine > General issues > Public health & preventive medicine > Epidemiology & medical statistics Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
LSN:	1-4899-8531-X
Barcode:	9781489985316

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