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Books > Professional & Technical > Biochemical engineering > Biotechnology
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Cell and Matrix Mechanics (Paperback)
Loot Price: R2,447
Discovery Miles 24 470
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Cell and Matrix Mechanics (Paperback)
Expected to ship within 12 - 19 working days
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Explores a Range of Multiscale Biomechanics/Mechanobiology Concepts
Cell and Matrix Mechanics presents cutting-edge research at the
molecular, cellular, and tissue levels in the field of cell
mechanics. This book involves key experts in the field, and covers
crucial areas of cell and tissue mechanics, with an emphasis on the
roles of mechanical forces in cell-matrix interactions. Providing
material in each chapter that builds on the previous chapters, it
effectively integrates length scales and contains, for each length
scale, key experimental observations and corresponding quantitative
theoretical models. Summarizes the Three Hierarchical Levels of
Cell Mechanics The book contains 14 chapters and is organized into
three sections. The first section focuses on the molecular level,
the second section details mechanics at the cellular level, and the
third section explores cellular mechanics at the tissue level. The
authors offer a thorough description of the roles of mechanical
forces in cell and tissue biology, and include specific examples.
They incorporate descriptions of associated theoretical models, and
provide the data and modeling framework needed for a multi-scale
analysis. In addition, they highlight the pioneering studies in
cell-matrix mechanics by Albert K. Harris. The topics covered
include: The passive and active mechanical properties of
cytoskeletal polymers and associated motor proteins along with the
behavior of polymer networks The mechanical properties of the cell
membrane, with an emphasis on membrane protein activation caused by
membrane forces The hierarchical organization of collagen fibrils,
revealing that a delicate balance exists between specific and
nonspecific interactions to result in a structure with
semicrystalline order as well as loose associations The roles of
matrix mechanical properties on cell adhesion and function along
with different mechanical mechanisms of cell-cell interactions The
effects of mechanical loading on cell cytoskeletal remodeling,
summarizing various modeling approaches that explain possible
mechanisms regulating the alignment of actin stress fibers in
response to stretching The mechanical testing of cell-populated
collagen matrices, along with theory relating the passive and
active mechanical properties of the engineered tissues Cell
migration behavior in 3-D matrices and in collective cell motility
The role of mechanics in cartilage development The roles of both
cellular and external forces on tissue morphogenesis The roles of
mechanical forces on tumor growth and cancer metastasis Cell and
Matrix Mechanics succinctly and systematically explains the roles
of mechanical forces in cell-matrix biology. Practitioners and
researchers in engineering and physics, as well as graduate
students in biomedical engineering and mechanical engineering
related to mechanobiology, can benefit from this work.
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