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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases
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Bacterial Type III Protein Secretion Systems (Hardcover, 1st ed. 2020)
Loot Price: R3,346
Discovery Miles 33 460
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Bacterial Type III Protein Secretion Systems (Hardcover, 1st ed. 2020)
Series: Current Topics in Microbiology and Immunology, 427
Expected to ship within 18 - 22 working days
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One of the most exciting developments in the field of bacterial
pathogenesis in recent years is the discovery that many pathogens
utilize complex nanomachines to deliver bacterially encoded
effector proteins into eukaryotic and prokaryotic target cells to
modulate a variety of cellular functions for the pathogen's
benefit. These protein-delivery machines include the type III
secretion system (T3SS), which is widespread in nature and encoded
not only by bacteria pathogenic to vertebrates or plants, but also
by bacteria that are symbiotic to plants or insects. Because they
are essential virulence factors for many important human pathogens,
these systems are emerging as a prime target for the development of
new-generation, anti-infective drugs. This book reviews our current
understanding of these intriguing injection machines as well as of
the closely related T3SS that serves in flagella assembly.
Individual chapters focus on regulation, assembly, structure, and
function of the type III secretion machine and on the evolution of
the secreted effector proteins. Given its scope, this book will
appeal to a broad readership, including researchers and teachers in
the fields of infectious diseases, host pathogen interactions,
plant and animal pathogenesis, and symbiosis.
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