Bacterial Type III Protein Secretion Systems (Hardcover, 1st ed. 2020)

One of the most exciting developments in the field of bacterial pathogenesis in recent years is the discovery that many pathogens utilize complex nanomachines to deliver bacterially encoded effector proteins into eukaryotic and prokaryotic target cells to modulate a variety of cellular functions for the pathogen's benefit. These protein-delivery machines include the type III secretion system (T3SS), which is widespread in nature and encoded not only by bacteria pathogenic to vertebrates or plants, but also by bacteria that are symbiotic to plants or insects. Because they are essential virulence factors for many important human pathogens, these systems are emerging as a prime target for the development of new-generation, anti-infective drugs. This book reviews our current understanding of these intriguing injection machines as well as of the closely related T3SS that serves in flagella assembly. Individual chapters focus on regulation, assembly, structure, and function of the type III secretion machine and on the evolution of the secreted effector proteins. Given its scope, this book will appeal to a broad readership, including researchers and teachers in the fields of infectious diseases, host pathogen interactions, plant and animal pathogenesis, and symbiosis.

General

Imprint:	Springer Nature Switzerland AG
Country of origin:	Switzerland
Series:	Current Topics in Microbiology and Immunology, 427
Release date:	August 2020
First published:	2020
Editors:	Samuel Wagner • Jorge E. Galan
Dimensions:	235 x 155mm (L x W)
Format:	Hardcover
Pages:	230
Edition:	1st ed. 2020
ISBN-13:	978-3-03-052122-6
Categories:	Books > Medicine > Other branches of medicine > Pathology > Medical microbiology & virology Books > Science & Mathematics > Biology, life sciences > Microbiology (non-medical) > Bacteriology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases > General
LSN:	3-03-052122-2
Barcode:	9783030521226

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