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Atherogenesis and Aging (Paperback, Softcover reprint of the original 1st ed. 1987)
Loot Price: R2,908
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Atherogenesis and Aging (Paperback, Softcover reprint of the original 1st ed. 1987)
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Age is a nonreversible risk factor for atherosclerosis. The
atherosclerotic process begins early in life, progresses during the
middle years, and usually culminates in clinical disease towards
the later years of the life span. Since atherosclerosis is a
multifactorial disease, and many of the "risk factors" are time-
and age related, it has been difficult to sort out intrinsic aging
from environmental factors that operate over many years.
Furthermore, the role of genetic factors remains unknown. This
workshop has produced much worthwhile information that is helping
elucidate the impact of age on atherogenesis. Important strides
have been made in understanding the role of changes in the arterial
wall and of lipoproteins, platelets, and monocyte-derived
macrophages in the disease process. In parallel, our understanding
of the biology of aging has increased sufficiently so that these
two areas of interest can now profitably intersect. The proceedings
of this successful workshop emphasize that there is much to be
gained by continued interaction between those scientists interested
in the biology of aging at all levels and those interested in the
atherosclerotic process. Hopefully, we may eventually progress in
our understanding and reach the stage when atherosclerosis will no
longer be an inexorable concomitant of human aging. Edwin L.
Bierman, M. D. Contents Foreword V Contributors IX Participants in
the Workshop XV Introduction and Statement of Research
Recommendations Sandra R."
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