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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Role of Capsaicin in Oxidative Stress and Cancer (Paperback, 2013 ed.)
Loot Price: R3,276
Discovery Miles 32 760
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Role of Capsaicin in Oxidative Stress and Cancer (Paperback, 2013 ed.)
Series: Diet and Cancer, 3
Expected to ship within 10 - 15 working days
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This book describes the mechanism of the anti-cancer effects of
capsaicin including the involvement of cytochrome P-450 in the
bioactivation; identification of mitochondria as the key target
site for oxidative stress; involvement of mitochondrial respiratory
chain in the production of ROS; prevention of chemically-induced
carcinogenesis, discussion on TRPV-1 receptor mediated or
independent anti-cancer effects; identification of p53 activation
as a possible mechanism; involvement of Cox-2 in apoptosis,
suppression of transcription factors such as NF-kB and STAT-3;
inhibition of cell survival pathways including PI3K/Akt and the
involvement of intrinsic mitochondrial cell death pathway.
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