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Books > Professional & Technical > Biochemical engineering > Biotechnology
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Thyroid Systems Engineering - A Primer in Mathematical Modeling of the Hypothalamus-Pituitary-Thyroid Axis (Hardcover)
Loot Price: R2,722
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Thyroid Systems Engineering - A Primer in Mathematical Modeling of the Hypothalamus-Pituitary-Thyroid Axis (Hardcover)
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In recent years, a considerable amount of effort has been devoted,
both in industry and academia, towards the behavioral modeling,
evaluation and prediction of the hypothalamus pituitary thyroid
system. Thyroid Systems Engineering targets an optimal treatment of
people suffering from thyroid hormone disorders. The content is
motivated by in-depth observations of such patients whose rich data
supported the theoretical framework arising from formal
mathematical reasoning, guided by the nature of thyroid physiology.
Leveraging on the insights emerging from the unique combination of
an electrical engineer working with a clinical thyroidologist, and
both being scientists skilled in mathematics, the authors introduce
this new discipline and field of scientific investigation aptly
designated as Thyroid Systems Engineering. Readers will discover
that mathematics can indeed model the behavior of the
hypothalamus-pituitary-thyroid (HPT) axis. Focused on modeling,
each of the eighteen chapters gives the reader a notion of the
application of relevant mathematics to pertinent issues encountered
in mainstream thyroidology. Many cellular processes resemble the
flux of variables and states in a complex multi-parameter space
through time analogous to current flow in electrical networks. It
is then logical to apply the principles and physical laws of
electrodynamics, electrical network theory, control systems theory
and signal theory to many of the biological phenomena encountered
in endocrinology. Such an approach is used liberally throughout the
book and successfully yields elegant solutions to a number of
models presented within. This book can serve as a reference to
mathematical modeling in other aspects of endocrine physiology, and
as the starting point for a fundamental course in medical modeling.
It will appeal to postgraduates in electrical engineering, academic
physicians and biomedical researchers. Further, readers equipped
with advanced calculus, electrical network theory, control theory
and signal theory should be able to follow the mathematical
expositions that describe thyrotropic control. They represent a new
discipline based on mathematical modeling in physiology applicable
to medical diagnostics, measurement and treatment to cooperate in
the clinical team and realize an optimized treatment for patients.
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