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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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Calcitonin Gene-Related Peptide (CGRP) Mechanisms - Focus on Migraine (Hardcover, 1st ed. 2019)
Loot Price: R3,800
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Calcitonin Gene-Related Peptide (CGRP) Mechanisms - Focus on Migraine (Hardcover, 1st ed. 2019)
Series: Handbook of Experimental Pharmacology, 255
Expected to ship within 10 - 15 working days
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This book is designed to focus on the role of Calcitonin
Gene-Related Peptide (CGRP) in health and disease. This peptide,
originally discovered in the 1980s as a sensory neuropeptide with
cardiovascular effects, is now known to play a distinct role in the
pain processing of migraine. The various chapters address the
origin, localization and function of CGRP and its receptor in the
peripheral nervous system, in the cardiovascular system, and in
other tissues and organs. Further attention is paid to the drug
discovery pathway where recent findings show the beneficial effect
of small molecule antagonists of the CGRP receptors for the relief
of the migraine attack and of monoclonal antibodies against CGRP or
the CGRP receptor for migraine prevention.
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