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Molecular Pathogenesis of Gastrointestinal Infections (Paperback, Softcover reprint of the original 1st ed. 1991)
Loot Price: R1,628
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Molecular Pathogenesis of Gastrointestinal Infections (Paperback, Softcover reprint of the original 1st ed. 1991)
Series: F.E.M.S. Symposium Series, 58
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The meeting that provided the material for this book was the 58th
Symposium of the Federation of European Microbiological Societies
(FEMS) entitled MOLECULAR PATHOGENESIS OF GASTROINTESTINAL
INFECTIONS which was held in Helsingor, Denmark from 2nd to 4th
September, 1990. The aim of this meeting was to bring together
scientists from a range of discipline- microbiology, cell biology,
molecular biology and immunology - to consider how microbes,
including parasites, colonize and infect the gastrointestinal
tract. The programme was designed to focus particular attention on
the range of strategies whereby enterovirulent bacteria and
parasites colonize the gastrointestinal mucin layer, how they
adhere to and penetrate the epithelial layer by entering the cells
or passing between them, and how various protein toxins may
facilitate these processes. Speakers were especially encouraged to
highlight the recent expansion in our knowledge of the molecular
mechanisms by which enterotoxigenic and enteropathogenic
Escherichia coli, shigellae, salmonellae and Yersinia
enterocolitica cause intestinal disease. There were also
discussions of recently-discovered gastrointestinal pathogens such
as Clostridium difficile and Helicobacter pylori as well as
accounts of how virulent determinants can be used to develop new
diagnostic methods based on DNA gene probes and the polymerase
chain reaction (PCR). These presentations provided the basis for
the chapters in this book.
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