Thymic Development and Selection of T Lymphocytes (Paperback, Softcover reprint of the original 1st ed. 2014)

The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Current Topics in Microbiology and Immunology, 373
Release date:	August 2016
First published:	2014
Editors:	Thomas Boehm • Yousuke Takahama
Dimensions:	235 x 155 x 8mm (L x W x T)
Format:	Paperback
Pages:	132
Edition:	Softcover reprint of the original 1st ed. 2014
ISBN-13:	978-3-662-51196-1
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN:	3-662-51196-7
Barcode:	9783662511961

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