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Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease (Hardcover, 2012 ed.)
Loot Price: R5,707
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Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease (Hardcover, 2012 ed.)
Series: Subcellular Biochemistry, 60
Expected to ship within 10 - 15 working days
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Cell-cell adhesion is fundamental for the development and
homeostasis of animal tissues and organs. Adherens junctions (AJs)
are the best understood cell-cell adhesion complexes. In this
volume, internationally recognized experts review AJ biology over a
wide range of organization; from atoms to molecules, to protein
complexes, molecular networks, cells, tissues, and overall animal
development. AJs have also been an integral part of animal
evolution, and play central roles in cancer development, pathogen
infection and other diseases. This book addresses major questions
encompassing AJ biology. - How did AJs evolve? - How do cadherins
and catenins interact to assemble AJs and mediate adhesion? - How
do AJs interface with other cellular machinery to couple adhesion
with the whole cell? - How do AJs affect cell behaviour and
multicellular development? - How can abnormal AJ activity lead to
disease? Valuable for both newcomers and experts in the field, this
book offers a comprehensive resource for the research laboratory
and a teaching tool for advanced undergraduate and graduate courses
in cell and developmental biology.
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