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Books > Science & Mathematics > Biology, life sciences > Biochemistry > Carbohydrates
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The Carbonic Anhydrases - New Horizons (Hardcover, 2000 ed.)
Loot Price: R7,831
Discovery Miles 78 310
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The Carbonic Anhydrases - New Horizons (Hardcover, 2000 ed.)
Series: Experientia Supplementum, 90
Expected to ship within 18 - 22 working days
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Carbonic anhydrase (CA) is a seemingly ubiquitous enzyme of
profound physiological importance, which plays essential roles in
respiration, acid-base homeostasis, bone resorption, calcification,
photosynthesis, several biosynthetic pathways and a variety of
processes involving ion, gas and fluid transfer. This enzyme, which
is present in at least three gene families (a, ss, ?), has found
favour as a model for the study of evolution of gene families and
for site-directed mutagenesis in structure/function relationships,
for protein folding and for transgenic and gene target studies.
Since the early use of CA inhibitors as diuretics and in treating
congestive heart failure, the enzyme has been target of
considerable clinical attention. Much of this is now focused on
endeavours to produce a new generation of such drugs for the
effective treatment of glaucoma and other potential applications.
Recent data, suggesting links between CA and various disease
processes, including cancer, have stimulated further...
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