The Carbonic Anhydrases - New Horizons (Hardcover, 2000 ed.)

Carbonic anhydrase (CA) is a seemingly ubiquitous enzyme of profound physiological importance, which plays essential roles in respiration, acid-base homeostasis, bone resorption, calcification, photosynthesis, several biosynthetic pathways and a variety of processes involving ion, gas and fluid transfer. This enzyme, which is present in at least three gene families (a, ss, ?), has found favour as a model for the study of evolution of gene families and for site-directed mutagenesis in structure/function relationships, for protein folding and for transgenic and gene target studies. Since the early use of CA inhibitors as diuretics and in treating congestive heart failure, the enzyme has been target of considerable clinical attention. Much of this is now focused on endeavours to produce a new generation of such drugs for the effective treatment of glaucoma and other potential applications. Recent data, suggesting links between CA and various disease processes, including cancer, have stimulated further...

General

Imprint:	Birkhauser Verlag AG
Country of origin:	Switzerland
Series:	Experientia Supplementum, 90
Release date:	October 2000
First published:	2000
Editors:	W. R. Chegwidden • N.D. Carter • Y.H. Edwards
Dimensions:	235 x 155 x 35mm (L x W x T)
Format:	Hardcover
Pages:	619
Edition:	2000 ed.
ISBN-13:	978-3-7643-5670-5
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > Carbohydrates Books > Science & Mathematics > Biology, life sciences > Biochemistry > Enzymology
LSN:	3-7643-5670-7
Barcode:	9783764356705

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