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Critical Analysis of Monoclonal Antibody Therapy in Transplantation (Hardcover)
Loot Price: R8,178
Discovery Miles 81 780
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Critical Analysis of Monoclonal Antibody Therapy in Transplantation (Hardcover)
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Critical Analysis of Monoclonal Antibody Therapy in Transplantation
provides a critical analysis of monoclonal antibody therapies in
transplantation. The book presents diverse approaches to monoclonal
antibody therapy in transplantation and addresses some of the
serious obstacles that remain both in understanding these
mechanisms and in successfully applying them in clinical
situations. The background and rationale for OKT3 therapy are
examined and an extensive clinical experience with OKT3 induction
therapy in cardiac transplantation is reviewed. The book also
examines the background and rationale for the use of anti-TcR ( ),
anti-IL-2R, and anti-LFA-1 monoclonal antibodies in clinical
transplantations. Other topics include the use of monclonal
antibodies to CD4 and CD8 for the induction of adult
transplantation tolerance in rodents and the possibilities for
applying anti-idiotypical strategies that have proven useful in
autoimmunity models to transplant recipients. Researchers and basic
scientists involved in this field will find the book a fascinating
and useful resource for their investigations.
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