Biologics and Biosimilars: Drug Discovery and Clinical Applications
is a systematic integration and evaluation of all aspects of
biologics and biosimilars, encompassing research and development,
clinical use, global regulation, and more. Biosimilars are
biological therapeutic agents designed to imitate a reference
biologic with high similarities in structure, efficacy, and safety,
but also with potential clinical effective and cost-efficient
options for the manufacturers, payers, clinicians, and patients.
Most of the top-selling prescription drugs in the current market
are biologics, which have revolutionized the treatment strategies
and modalities for life-threatening and/or rare diseases. This book
outlines the key processes and challenges in drug development,
regulations, and clinical applications of biologics, biosimilars,
and even interchangeable biosimilars. Global experts in the field
discuss essential categories and prototype drugs of biologics and
biosimilars in clinical practice such as allergenics, blood and
blood components, cell treatment, gene therapy, recombinant
therapeutic proteins or peptides, tissues, and vaccines. Additional
features: Integrates the latest bench and bedside evidence of drug
development and regulations of biologics and biosimilars Contains
key study questions for each chapter to guide the readers, as well
as drug charts for all therapeutic applications of biologics and
biosimilars Presents detailed schematic illustrations to explain
the drug development, clinical trials, regulations, and clinical
applications of biologics and biosimilars This book is an
invaluable tool for health care professional students, providers,
and pharmaceutical and health care industries, as well as the
public, providing readers with educational updates about the drug
development and clinical affairs of biological medications and
their similar drugs.
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