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MicroRNA Detection and Pathological Functions (Paperback, 2015 ed.)
Loot Price: R1,891
Discovery Miles 18 910
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MicroRNA Detection and Pathological Functions (Paperback, 2015 ed.)
Series: SpringerBriefs in Molecular Science
Expected to ship within 10 - 15 working days
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This book summarizes microRNA (miRNA) biology in a variety of
pathological processes, emphasizing the significant potential
applications of miRNA in diagnostics and prognostics, as well as
novel drug targets. The conventional techniques used for miRNA
detection including standard PCR, Northern blotting, microarray and
clone methods are addressed. Recent emerging strategies in miRNA
detection and quantification with superior flexibility and
adaptability, such as novel molecular biological techniques and
locked nucleic acid (LNA) modified probes, as well as
nanotechnology-based approaches, are also included. The book also
highlights the latest advances in clinical-related miRNA detection
methods in living cells, circulating blood and tissue, such as in
situ hybridization (ISH) and molecular imaging techniques, which
are useful to elucidate the biogenesis and biological function of
miRNAs in vivo. Finally, the respective advantages and drawbacks of
various detection techniques in this fast-moving field are
discussed, along with the challenges and promising new directions.
This book offers a valuable resource for analytical chemists,
biologists and physicians involved in miRNA research. Dr. Xueji
Zhang and Dr. Haifeng Dong are Professors at the School of
Chemistry & Biological Engineering, University of Science &
Technology Beijing (USTB), China. Dr. Yaping Tian is a Professor at
the Department of Clinical Biochemistry, Chinese PLA General
Hospital and Military Medical School, China.
General
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