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Influenza - Molecular Virology (Hardcover)
Loot Price: R5,974
Discovery Miles 59 740
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Influenza - Molecular Virology (Hardcover)
Expected to ship within 10 - 15 working days
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In the last 100 years, there have been three major influenza
pandemics: the Spanish Flu in 1918, the Asian Flu in 1957, and the
Hong Kong Flu in 1968. These pandemics claimed the lives of
approximately 50 million, 2 million, and 1 million people
respectively. Added to this is the annual death toll from influenza
of 250,000 to 500,000 people worldwide, with a further 3 to 4
million people suffering severe illness. These statistics make
influenza an extremely important pathogen. In 1997, the alarming
emergence of a new, highly pathogenic subtype, H5N1, which has a
50% mortality rate, provided a major impetus for renewed influenza
research. However, the battle against influenza is difficult.
Recently another subtype, H1N1, has emerged. This subtype causes a
relatively mild infection in humans, however it is highly
transmittable between people and a new influenza pandemic has been
declared by the World Health Organization. If this virus were to
acquire some of the lethal capabilities of H5N1, then the ensuing
pandemic could be devastating. In this timely book, internationally
renowned scientists critically review the current research and the
most important discoveries in this highly topical field. Subjects
covered include the NS1 protein of influenza A virus, the structure
of influenza NS1, influenza B hemagglutinin, influenza A
nucleoprotein, influenza A hemagglutinin glycoproteins, the M2
channel, virulence genes of the 1918 H1N1 influenza, influenza
virus polymerase, gene diagnostic microarrays, and
computer-assisted vaccine design. Highly informative and well
referenced, Influenza: Molecular Virology is essential reading for
all influenza specialists and is recommended reading for all
virologists, immunologists, molecular biologists, public health
scientists, and research scientists in pharmaceutical companies.
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