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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Gene Therapy for Autoimmune and Inflammatory Diseases (Paperback, 2010 ed.)
Loot Price: R5,850
Discovery Miles 58 500
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Gene Therapy for Autoimmune and Inflammatory Diseases (Paperback, 2010 ed.)
Series: Milestones in Drug Therapy
Expected to ship within 10 - 15 working days
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In this monograph about gene therapy of autoimmune and inflammatory
d- orders we have gathered international experts and leaders from
different fields to review the state of the art advances on topics
ranging from disease entities to vectors and engineered cells. The
different approaches described in each chapter take into
consideration the biomedical knowledge of these diseases and
address the complexities of delivering long-term genetic
interventions. Gene therapy also serves as a testing ground for new
therapeutic entities and helps provide proof of principle for their
potential therapeutic role in animal models of disease. Scaling up
from mice to men still remains an important h- dle not only from
the quantitative point of view, but also for currently unknown and
unexpected secondary effects of the vector or the transgene. Some
of these approaches have already been tested in the clinic, but
much more needs to be done to understand the human conditions
treated and the n- ural history of their pathology. We are indebted
to the secretarial assistance of Ms. Lin Wells (Bone and Joint
Research Unit, London, UK) and the help of Hans Detlef Kluber for
his help in getting this book published. We hope this book will be
of interest to c- nicians and scientists and inspiring to students
of the subject who will use their own ingenuity and knowledge to
further forward this discipline into clinical use.
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