Gene Therapy for Autoimmune and Inflammatory Diseases (Paperback, 2010 ed.)

In this monograph about gene therapy of autoimmune and inflammatory d- orders we have gathered international experts and leaders from different fields to review the state of the art advances on topics ranging from disease entities to vectors and engineered cells. The different approaches described in each chapter take into consideration the biomedical knowledge of these diseases and address the complexities of delivering long-term genetic interventions. Gene therapy also serves as a testing ground for new therapeutic entities and helps provide proof of principle for their potential therapeutic role in animal models of disease. Scaling up from mice to men still remains an important h- dle not only from the quantitative point of view, but also for currently unknown and unexpected secondary effects of the vector or the transgene. Some of these approaches have already been tested in the clinic, but much more needs to be done to understand the human conditions treated and the n- ural history of their pathology. We are indebted to the secretarial assistance of Ms. Lin Wells (Bone and Joint Research Unit, London, UK) and the help of Hans Detlef Kluber for his help in getting this book published. We hope this book will be of interest to c- nicians and scientists and inspiring to students of the subject who will use their own ingenuity and knowledge to further forward this discipline into clinical use.

General

Imprint:	Springer Basel
Country of origin:	Switzerland
Series:	Milestones in Drug Therapy
Release date:	July 2012
First published:	2010
Editors:	Yuti Chernajovsky • Paul D. Robbins
Dimensions:	235 x 165mm (L x W)
Format:	Paperback
Pages:	239
Edition:	2010 ed.
ISBN-13:	978-3-03-480306-9
Categories:	Books > Medicine > Clinical & internal medicine > Rheumatology Books > Medicine > Clinical & internal medicine > Gene therapy Books > Medicine > General issues > Medical equipment & techniques > Medical research Books > Medicine > Other branches of medicine > Pharmacology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General Promotions
LSN:	3-03-480306-0
Barcode:	9783034803069

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