To what extent should we use technology to try to make better human beings? Because of the remarkable advances in biomedical science, we must now find an answer to this question.
Human enhancement aims to increase human capacities above normal levels. Many forms of human enhancement are already in use. Many students and academics take cognition enhancing drugs to get a competitive edge. Some top athletes boost their performance with legal and illegal substances. Many an office worker begins each day with a dose of caffeine. This is only the beginning. As science and technology advance further, it will become increasingly possible to enhance basic human capacities to increase or modulate cognition, mood, personality, and physical performance, and to control the biological processes underlying normal aging. Some have suggested that such advances would take us beyond the bounds of human nature.
These trends, and these dramatic prospects, raise profound ethical questions. They have generated intense public debate and have become a central topic of discussion within practical ethics. Should we side with bioconservatives, and forgo the use of any biomedical interventions aimed at enhancing human capacities? Should we side with transhumanists and embrace the new opportunities? Or should we perhaps plot some middle course?
Human Enhancement presents the latest moves in this crucial debate: original contributions from many of the world's leading ethicists and moral thinkers, representing a wide range of perspectives, advocates and sceptics, enthusiasts and moderates. These are the arguments that will determine how humanity develops in the near future.

As DNA forensic profiling and databasing become established as key technologies in the toolbox of the forensic sciences, their expanding use raises important issues that promise to touch everyone's lives. In an authoritative global investigation of a diverse range of countries, including those at the forefront of these technologies' development and use, this book identifies and provides critical reflection upon the many issues of privacy; distributive justice; DNA information system ownership; biosurveillance; function creep; the reliability of collection, storage and analysis of DNA profiles; the possibility of transferring medical DNA information to forensics databases; and democratic involvement and transparency in governance, an emergent key theme. This book is timely and significant in providing the essential background and discussion of the ethical, legal and societal dimensions for academics, practitioners, public interest and criminal justice organisations, and students of the life sciences, law, politics, and sociology.

The past two decades have seen unparalleled developments in our knowledge of the brain and mind. However, these advances have forced us to confront head-on some significant ethical issues regarding our application of this information in the real world- whether using brain images to establish guilt within a court of law, or developing drugs to enhance cognition. Historically, any consideration of the ethical, legal, and social implications of emerging technologies in science and medicine has lagged behind the discovery of the technology itself. These delays have caused problems in the acceptability and potential applications of biomedical advances and posed significant problems for the scientific community and the public alike - for example in the case of genetic screening and human cloning. The field of Neuroethics aims to proactively anticipate ethical, legal and social issues at the intersection of neuroscience and ethics, raising questions about what the brain tells us about ourselves, whether the information is what people want or ought to know, and how best to communicate it. A landmark in the academic literature, the Oxford Handbook of Neuroethics presents a pioneering review of a topic central to the sciences and humanities. It presents a range of chapters considering key issues, discussion, and debate at the intersection of brain and ethics. The handbook contains more than 50 chapters by leaders from around the world and a broad range of sectors of academia and clinical practice spanning the neurosciences, medical sciences and humanities and law. The book focuses on and provides a platform for dialogue of what neuroscience can do, what we might expect neuroscience will do, and what neuroscience ought to do. The major themes include: consciousness and intention; responsibility and determinism; mind and body; neurotechnology; ageing and dementia; law and public policy; and science, society and international perspectives. Tackling some of the most significant ethical issues that face us now and will continue to do so over the coming decades, The Oxford Handbook of Neuroethics will be an essential resource for the field of neuroethics for graduate students and postdoctoral fellows, basic scientists in the neurosciences and psychology, scholars in humanities and law, as well as physicians practising in the areas of primary care in neurological medicine.

T. H. Huxley (1825-1895) was not only an active protagonist in the religious and scientific upheaval that followed the publication of Darwin's theory of evolution but also a harbinger of the sociobiological debates about the implications of evolution that are now going on. His seminal lecture Evolution and Ethics, reprinted here with its introductory Prolegomena, argues that the human psyche is at war with itself, that humans are alienated in a cosmos that has no special reference to their needs, and that moral societies are of necessity in conflict with the natural conditions of their existence. Seen in the light of current understanding of the mechanisms of evolution, these claims remain as controversial today as they were when Huxley proposed them. In this volume George Williams, one of the best-known evolutionary biologists of our time, asserts that recent biological ideas and data justify a more extreme condemnation of the "cosmic process" than Huxley advocated and more extreme denial that the forces that got us here are capable of maintaining a viable world. James Paradis, an expert in Victorian studies, has written an introduction that sets the celebrated lecture in the context of cultural history, revealing it to be an impressive synthesis of Victorian thinking, as well as a challenge to eighteenth-century assumptions about the harmony of of nature. With Huxley's lecture as a focal point, the three parts of this book unite philosophy and science in a shared quest that recalls their common origins as systems of knowledge. Originally published in 1989. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

This volume maps the areas of ethical concern in the debate regarding the governance of genetic information, and suggests alternative ethical frameworks and models of regulation in order to inform its restructuring. Genetic governance is at the heart of medical and scientific developments, and is connected to global exploitation, issues of commodification, commercialisation and ownership, the concepts of property and intellectual property and concerns about individual and communal identity. Thus the decisions that are made in the next few years about appropriate models of genetic governance will have knock-on effects for other areas of governance. In short the final answer to 'Who Decides?' in the context of genetic governance will fundamentally shape the ethical constructs of individuals and their networks and relationships in the public sphere.

Bioscience ethics facilitates free and accurate information transfer from applied science to applied bioethics. Its major elements are: increased understanding of biological systems, responsible use of technology, and attuning ethnocentric debates to new scientific insights. Pioneered by Irina Pollard in 1994, bioscience ethics has become an internationally recognized discipline, interfacing science and bioethics within professional perspectives such as medical, legal, bio-engineering, and economics. Written for students and professionals alike, the fundamental feature of this book is its breadth, important because bioscience ethics interweaves many diverse subjects in the process of gathering specialist scientific knowledge for bioethical review. It contains chapters which embrace topics affecting human reproduction, end-of-life care and euthanasia, challenge human-dominated ecosystems, and review population growth, economic activity and warfare. A background section describes the evolution of ethical consciousness, explores the future, and proposes that the reworking of ethical boundaries can enhance mature decision-making in harmony with changing technology.

Informed consent is a central topic in contemporary biomedical ethics. Yet attempts to set defensible and feasible standards for consenting have led to persistent difficulties. In Rethinking Informed Consent in Bioethics, first published in 2007, Neil Manson and Onora O'Neill set debates about informed consent in medicine and research in a fresh light. They show why informed consent cannot be fully specific or fully explicit, and why more specific consent is not always ethically better. They argue that consent needs distinctive communicative transactions, by which other obligations, prohibitions, and rights can be waived or set aside in controlled and specific ways. Their book offers a coherent, wide-ranging and practical account of the role of consent in biomedicine which will be valuable to readers working in a range of areas in bioethics, medicine and law.

Informed consent is a central topic in contemporary biomedical ethics. Yet attempts to set defensible and feasible standards for consenting have led to persistent difficulties. In Rethinking Informed Consent in Bioethics, first published in 2007, Neil Manson and Onora O'Neill set debates about informed consent in medicine and research in a fresh light. They show why informed consent cannot be fully specific or fully explicit, and why more specific consent is not always ethically better. They argue that consent needs distinctive communicative transactions, by which other obligations, prohibitions, and rights can be waived or set aside in controlled and specific ways. Their book offers a coherent, wide-ranging and practical account of the role of consent in biomedicine which will be valuable to readers working in a range of areas in bioethics, medicine and law.

In this volume, F.M. Kamm explores how theories as well as hypothetical and practical cases help us understand rights and their limits. The book begins by considering moral status and its relation to having rights (including whether non-human animals have rights and what rights future persons have). The author then considers whether rights are grounded in duties to oneself, which duties are correlative to rights, and whether neuroscientific and psychological studies can help determine what rights we have. Kamm next investigates the contours of the right not to be harmed by considering critiques of deontological distinctions, the costs that must be undertaken to avoid harming, and a proposal for permissibly harming someone (that allows for resisting the harm) in the Trolley Problem. Additional chapters cover possible implications of the Trolley Problem for such practical issues as correctly programming self-driving cars, providing medical treatments, and enacting redistributive economic policy. Kamm concludes the book by comparing the use of case-based judgments about extreme cases in moral versus aesthetic theory, and by exploring the significance of the right not to be harmed for morally correct policies in the extreme cases of torture and a pandemic. Where pertinent, Kamm considers the views of Derek Parfit, Tom Regan, Christine Korsgaard, Shelly Kagan, Ronald Dworkin, Amartya Sen, Allan Gibbard, Joshua Greene, Arthur Danto, and Judith Thomson, among others.

T. H. Huxley (1825-1895) was not only an active protagonist in the religious and scientific upheaval that followed the publication of Darwin's theory of evolution but also a harbinger of the sociobiological debates about the implications of evolution that are now going on. His seminal lecture Evolution and Ethics, reprinted here with its introductory Prolegomena, argues that the human psyche is at war with itself, that humans are alienated in a cosmos that has no special reference to their needs, and that moral societies are of necessity in conflict with the natural conditions of their existence. Seen in the light of current understanding of the mechanisms of evolution, these claims remain as controversial today as they were when Huxley proposed them. In this volume George Williams, one of the best-known evolutionary biologists of our time, asserts that recent biological ideas and data justify a more extreme condemnation of the "cosmic process" than Huxley advocated and more extreme denial that the forces that got us here are capable of maintaining a viable world. James Paradis, an expert in Victorian studies, has written an introduction that sets the celebrated lecture in the context of cultural history, revealing it to be an impressive synthesis of Victorian thinking, as well as a challenge to eighteenth-century assumptions about the harmony of of nature. With Huxley's lecture as a focal point, the three parts of this book unite philosophy and science in a shared quest that recalls their common origins as systems of knowledge.

Originally published in 1989.

The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These paperback editions preserve the original texts of these important books while presenting them in durable paperback editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

How to avoid disease, how to breed successfully and how to live to a reasonable age, are questions that have perplexed mankind throughout history. This 2005 book explores our progress in understanding these challenges, and the risks and rewards of our attempts to find solutions. From the moment of conception, nutrition and exposure to microbes or alien chemicals have consequences that are etched into our cells and genomes. Such events have a crucial impact on development in utero and in childhood, and later, on the way we age, respond to infection, or the likelihood of developing chronic diseases, including cancer. The issues covered include the powerful influence of infectious disease on human society, the burden of our genetic legacy and the lottery of procreation. The author discusses how prospects for human life might continually improve as biomedicine addresses these problems and also debates the ethical checkpoints encountered.

This textbook untangles the complicated ethical dilemmas that arise during the day-to-day work of healthcare chaplaincy, and offers a sturdy but flexible framework which chaplains can use to reflect on their own practice. Tackling essential issues such as consent, life support, abortion, beginning and end of life and human dignity, it enables chaplains to tease out the ethical implications of situations they encounter, to educate themselves on relevant legal matters and to engage with different ethical viewpoints. The book combines case studies of familiar scenarios with thorough information on legal matters, while providing ample opportunity for workplace reflection and offering guidance as to how chaplains can best support patients and their families while preserving their own integrity and well-being. Clear, sensitive and user-friendly, this will be an indispensable resource for healthcare chaplains and all healthcare professionals interested in spiritual care.

There is the world of ideas and the world of practice; the French are often for sup pressing the one and the English the other; but neither is to be suppressed. -Matthew Arnold The Function of Criticism at the Present Time From its inception, bioethics has confronted the need to reconcile theory and practice. At first the confrontation was purely intellectual, as writers on ethical theory (within phi losophy, theology, or other humanistic disciplines) turned their attention to topics from the world of medical practice. Recently the confrontation has grown more intense. The ap pointment of clinical ethicists in hospitals and other health care settings is an accelerating trend in North America. Concomitantly, those institutions involved in training peo ple in clinical ethics have added organized exposure to the world of practice, in the form of placement requirements, to the normal academic course load. In common with other dis ciplines, bioethics has begun to see clinical training as a con dition of didactic theory and apprenticeship."

This is the second edition of a highly successful and well-received textbook on the responsible conduct of biomedical and health science research. It is aimed at faculty and graduate students in health science and biomedical science programs. In addition, those on National Institute of Health research grants, administrators at universities, and academic health centers will find it a useful resource. The major changes include new chapters providing overviews of each topic, several new published articles added to the readings, revised case studies as well as further readings and web addresses.

Fifteen philosophers, social scientists, and academic lawyers assess various aspects of bioethics. Some detail its development and challenge the field's basic assumptions. Others consider bioethics's role in contemporary society and examine it in policy administration as well as in its interaction with other branches of philosophical inquiry. Chapters also focus on specific issues, including the responsibilities of researchers to subjects in clinical trials; the proper criteria for determining when a living organism has died; the allocation of scarce, life-saving medical resources; and the subsidization of pharmaceutical products for those who may be deprived of the benefits of modern medicine.

Onora O'Neill suggests that the conceptions of individual autonomy (so widely relied on in bioethics) are philosophically and ethically inadequate; they undermine rather than support relationships based on trust. Her arguments are illustrated with issues raised by such practices as the use of genetic information by the police, research using human tissues, new reproductive technologies, and media practices for reporting on medicine, science and technology. The study appeals to a wide range of readers in ethics, bioethics and related disciplines.

Little more than a decade ago the term "genetic engineering" was hardly known outside research laboratories. Today it regularly makes headlines. Those in favor of genetic engineering--and those against it--tell us that it has the potential to change our lives perhaps more than any other scientific or technological advance. But what are the likely consequences of genetic engineering? Is it ethically acceptable? Should we be trying to improve on nature? In Improving Nature?, the authors, a biologist and a moral philosopher, examine the implications of genetic engineering in every aspect of our lives. The underlying science is clearly explained and the moral and ethical considerations are fully disussed, resulting in a wide-ranging, balanced overview of a controversial subject. Michael Jonathan Reiss, a biologist, is Professor of Science Education and Head of Science & Technology, University of London Institute of Education. He is the author of Understanding Science Lessons (Open University Press, 2000). Roger Straughan is Reader in Education at the University of Reading. He is the author of Beliefs, Behaviour and Education (Cassell Academic, 1989). Previous paperback edition (1996) 0-521-63754-6

The explosive growth of science and medicine in recent times has raised a host of ethical issues. This book reviews major advances in biology and medicine and explores their ethical implications. Organized by stage of human life--from birth to death--it guides the reader through the critical issues that face our technologically advanced society. Each section contains a sketch of the scientific research in a particular field and then discusses the issues that challenge our ethical and moral principles, social frameworks, and public policies. A world-class group of contributors from biology, medicine, technology, and ethics probe controversial topics such as genetic research, transplantation, reproductive technologies, prolonging life and euthanasia, and research on animals and humans. The essays are concise, to the point, and deliberately free of jargon, and the entire work is framed by an introduction and postscript that point the way to the major questions. This book is the perfect introduction for novice readers with general or specific questions about the ethical issues raised by the rapid advance of science and technology. David Thomasma has written many books on medical ethics including For the Patient's Good and Euthanasia: Toward an Ethical Social Policy. He and Thomasine Kushner are the editors of the journal Cambridge Quarterly of Healthcare Ethics.

This book is a collection of essays by scientists, historians, philosophers of science, and students. The essays meld biotechnology into science fiction stories and thereby open a conversation about the morality of what we may be one day, and what it may mean to be human as our biotechnological endeavors continue to evolve. The biotechnology "revolution," launched on a global scale many decades ago, has taken a direct course toward re-creating life. Yet there are still many choices to be made in shaping the future that it may one day make possible. The book motivates readers toward deep reflection and continual discourse, which are essential if biotechnology is to evolve in ethical, meaningful, and sustainable ways.

This compact and innovative book tackles one of the central issues in drug policy: the lack of a coherent conceptual structure for thinking about drugs. Drugs generally fall into one of seven categories: prescription, over the counter, alternative medicine, common-use drugs like alcohol, tobacco and caffeine; religious-use, sports enhancement; and of course illegal street drugs like cocaine and marijuana. Our thinking and policies varies wildly from one to the other, with inconsistencies that derive more from cultural and social values than from medical or scientific facts. Penalties exist for steroid use, while herbal remedies or cold medication are legal. Native Americans may legally use peyote, but others may not. Penalties may vary for using different forms of the same drug, such as crack vs. powder cocaine. Herbal remedies are unregulated by the FDA; but medical marijuana is illegal in most states. Battin and her contributors lay a foundation for a wiser drug policy by promoting consistency and coherency in the discussion of drug issues and by encouraging a unique dialogue across disciplines. The contributors are an interdisciplinary group of scholars mostly based at the University of Utah, and include a pharmacologist, a psychiatrist, a toxicologist, a trial court judge, a law professor, an attorney, a diatary specialist, a physician, a health expert on substance abuse, and Battin herself who is a philosopher. They consider questions like the historical development of current policy and the rationales for it; scientific views on how drugs actually cause harm; how to define the key notions of harm and addiction; and ways in which drug policy can be made more consistent. They conclude with an examination of the implications of a consistent policy for various disciplines and society generally. The book is written accessibly with little need for expert knowledge, and will appeal to a diverse audience of philosophers, bioethicists, clinicians, policy makers, law enforcement, legal scholars and practitioners, social workers, and general readers, as well as to students in areas like pharmacy, medicine, law, nursing, sociology, social work, psychology, and bioethics.

Stem cell research. Drug company influence. Abortion. Contraception. Long-term and end-of-life care. Human participants research. Informed consent. The list of ethical issues in science, medicine, and public health is long and continually growing. These complex issues pose a daunting task for professionals in the expanding field of bioethics. But what of the practice of bioethics itself? What issues do ethicists and bioethicists confront in their efforts to facilitate sound moral reasoning and judgment in a variety of venues? Are those immersed in the field capable of making the right decisions? How and why do they face moral challenge -- and even compromise -- as ethicists? What values should guide them? In The Ethics of Bioethics, Lisa A. Eckenwiler and Felicia G. Cohn tackle these questions head on, bringing together notable medical ethicists and people outside the discipline to discuss common criticisms, the field's inherent tensions, and efforts to assign values and assess success. Through twenty-five lively essays examining the field's history and trends, shortcomings and strengths, and the political and policy interplay within the bioethical realm, this comprehensive book begins a much-needed critical and constructive discussion of the moral landscape of bioethics.

Mental health professionals face many complex questions in the course of their work with clients and patients. Among the most difficult are dilemmas that involve ethical issues. This book presents a forthright exploration of these dilemmas and the ethical considerations they raise. Drawing on extensive interviews, the author identifies common ethical problems that practitioners encounter. What happens, for example, when personal interests intrude into therapy? How can the therapist make an accurate assessment of his or her appropriateness as a care provider for a particular patient? What about confidentiality? How are problematic financial arrangements best addressed? The author goes on to show how these dilemmas may be intensified by the unique assumptions of different therapeutic orientations--individual, group, family, marital, and organizational--and how professionals can learn from such experiences to better understand and apply their particular approach. This analysis--and the words of the therapists themselves--provide both a guide to practice and a unique store of experience for the growing number of researchers and students concerned with ethical problems in psychotherapy.

Enhancing Human Capacities is the first to review the very latest scientific developments in human enhancement. It is unique in its examination of the ethical and policy implications of these technologies from a broad range of perspectives. * Presents a rich range of perspectives on enhancement from world leading ethicists and scientists from Europe and North America * The most comprehensive volume yet on the science and ethics of human enhancement * Unique in providing a detailed overview of current and expected scientific advances in this area * Discusses both general conceptual and ethical issues and concrete questions of policy * Includes sections covering all major forms of enhancement: cognitive, affective, physical, and life extension

In "Enhancing Evolution," leading bioethicist John Harris dismantles objections to genetic engineering, stem-cell research, designer babies, and cloning and makes an ethical case for biotechnology that is both forthright and rigorous. Human enhancement, Harris argues, is a good thing--good morally, good for individuals, good as social policy, and good for a genetic heritage that needs serious improvement. "Enhancing Evolution" defends biotechnological interventions that could allow us to live longer, healthier, and even happier lives by, for example, providing us with immunity from cancer and HIV/AIDS. Further, Harris champions the possibility of influencing the very course of evolution to give us increased mental and physical powers--from reasoning, concentration, and memory to strength, stamina, and reaction speed. Indeed, he says, it's not only morally defensible to enhance ourselves; in some cases, it's morally obligatory.

In a new preface, Harris offers a glimpse at the new science and technology to come, equipping readers with the knowledge to assess the ethics and policy dimensions of future forms of human enhancement.

von K. D. Bock Gestatten Sie, daB ich einleitend Sinn und Zweck dieses Kolloquiums kurz umreiBe. Risikofaktoren sind, vorbehaltlich einer genaueren, vielleicht auch etwas abweichenden Definition, die Herr Epstein in seinem einfuhrenden Referat geben wird, Haupt-oder Teilursachen von Krankheiten oder Krankheitskomplikationen. Sie zeichnen sich durch einige Besonderheiten aus, die es rechtfertigen, sie von der ku- rativen Medizin abzugrenzen und sie auch als Spezialfall der Praven- tivmedizin zu betrachten. Man kann zwei Arten von Risikofaktoren unterscheiden. Zum einen sind Risikofaktoren angeborene oder erworbene biologische Norm- abweichungen oder exogene Einwirkungen, die bei (noch) gesunden Individuen auftreten. Die Eigenschaft, noch nicht krank zu sein, hat der Risikofaktorentrager gemeinsam mit Personen, die z. B. einer Schutzimpfung unterzogen werden. Jedoch unterscheidet er sich von daB ihn das Risiko erstens permanent und zweitens diesen dadurch, immer auch personlich bedroht, wahrend z. B. bei einer Massen- schutzimpfung der einzelne vielleicht uberhaupt nicht oder nur zeit- weise dem Risiko einer Infektion ausgesetzt ist. Zum anderen wird aber auch eine bereits manifeste Krankheit als Risiko/aktor bezeich- net, wenn sie bestimmte Komplikationen allein-oder mitverursacht, z. B. die arterielle Hypertonie die Hirnblutung. Der Risikofaktorentrager erkrankt trotzdem nicht in jedem Faile und auch dann meist nach unterschiedlich langer Dauer der Einwirkung des Risikos. Insofern enthalt das Risikofaktorenkonzept ein progno- stisches Element, das nur in statistischer Form (mehr oder weniger genau) erfaBbar ist, jiir den konkreten Einze/fall aber keine Aussage zu- laj1t. Diese wichtige Tatsache wird in der praktischen Anwendung oft nicht berucksichtigt.