Nanobiotechnology is a fast developing field of research and application in many domains such as in medicine, pharmacy, cosmetics and agro-industry. The book addresses the lastest fundamental results on nanotoxicology and nanoethics, and the enormous range of potential applications in the fields of medical diagnostics, nanomedicine, and food and water administration. Nanoscale objects have properties leading to specific kinds of behaviour, sometimes exacerbating their chemical reactivity, physical behaviour, or potential to penetrate deeply within living organisms. Hence it is important to ensure the responsible and safe development of nanomaterials and nanotechnologies. This fourth volume in the Nanoscience series should make its mark, by presenting the state of the art in the fields of nanotoxicology and nanoethics. This is the first book to combine both scientific knowledge and ethical and social recommendations. It also presents specific policies on nanotechnologies set up by national and international authorities. This book is of interest to engineers, researchers, and graduate students.

At the time of the first edition of Principles of Cancer Biotherapy in 1987, this book represented the first comprehensive textbook on biological therapy. In 1991, when the second edition was published, there was still some doubt on the part of many oncologists and cancer researchers as to the therapeutic value of these new approaches. By 2003 and the fourth edition, it was generally agreed that biopharmaceuticals were producing major opportunities for new cancer therapies. Cancer biotherapy has now truly matured into the fourth modality of cancer treatment. This fifth revised edition describes the tremendous progress that has been made in recent years using biologicals in cancer treatment. This book summarizes an evolving science and a rapidly changing medical practice in biotherapy. In this new millennium, it is now possible to envision a much more diversified system of cancer research and treatment that will afford greater opportunities for a patient's personalized cancer treatment. This was first envisioned in the 1987 initial edition of this textbook and is now a "new" and popular approach to cancer treatment. Some forms of cancer biotherapy use the strategy of tumor stabilization and control through continued biological therapy, akin to the use of insulin in the treatment of diabetes. This textbook illustrates new methods of thinking and new strategies for control of cancer. It is always difficult to move from past dogma to future opportunity, but this fifth edition of Principles of Cancer Biotherapy illustrates why it is so important to the patients for researchers and clinicians to explore and quickly apply these new opportunities in cancer biotherapy.

This thought-provoking treatise argues that current human fertility rates are fueling a public health crisis that is at once local and global. Its analysis and data summarize the ecological costs of having children, presenting ethical dilemmas for prospective parents in an era of competition for scarce resources, huge disparities of wealth and poverty, and unsustainable practices putting irreparable stress on the planet. Questions of individual responsibility and integrity as well as personal moral and procreative issues are examined carefully against larger and more long-range concerns. The author's assertion that even modest efforts toward reducing global fertility rates would help curb carbon emissions, slow rising global temperatures, and forestall large-scale climate disaster is well reasoned and more than plausible. Among the topics covered: * The multiplier effect: food, water, energy, and climate. * The role of population in mitigating climate change. * The carbon legacy of procreation. * Obligations to our possible children. * Rights, what is right, and the right to do wrong. * The moral burden to have small families. Toward a Small Family Ethic sounds a clarion call for bioethics students and working bioethicists. This brief, thought-rich volume steers readers toward challenges that need to be met, and consequences that will need to be addressed if they are not.

This work sets the stage regarding debates about paternalism and health care for years to come. The anthology is organized around four parts: i) The concept of paternalism and theoretical issues regarding the idea of anti-paternalism, ii) strategies for justifying different forms of paternalism, iii) paternalism in psychiatry and psychotherapy, iv) paternalism and public health, and v) paternalism and reproductive medicine. Medical paternalism was arguably one of the main drivers of debates in medical ethics and has led to a wide acknowledgement of the value of patient autonomy. However, more recent developments in health care, such as the increasing significance of public health measures and the commercialization of medical services, have led to new social circumstances and hence to the need to rethink issues regarding paternalism. This work provides an invaluable source for many scholars and practitioners, since it deals in new and original ways with one of the main and oldest issue in health care ethics.

With the advance of biomedicine, certain individuals and groups are vulnerable because of their incapacities to defend themselves. The International Bioethics Committee as a UNESCO working group has for the last several years dedicated to deepen this principle of human vulnerability and personal integrity. This book serves to supplement this effort with a religious perspective given a great number of the world’s population is affiliated with some religious traditions. While there is diversity within each of these traditions, all of them carry in them the mission to protect the weak, the underprivileged, and the poor. Thus, here presented is a collection of papers written by bioethics experts from six major world religions—Buddhism, Christianity, Confucianism, Hinduism, Islam and Judaism—who were gathered to discuss the meaning and implications of the principle of vulnerability in their respective traditions.        

An argument that what makes science distinctive is its emphasis on evidence and scientists' willingness to change theories on the basis of new evidence. Attacks on science have become commonplace. Claims that climate change isn't settled science, that evolution is "only a theory," and that scientists are conspiring to keep the truth about vaccines from the public are staples of some politicians' rhetorical repertoire. Defenders of science often point to its discoveries (penicillin! relativity!) without explaining exactly why scientific claims are superior. In this book, Lee McIntyre argues that what distinguishes science from its rivals is what he calls "the scientific attitude"-caring about evidence and being willing to change theories on the basis of new evidence. The history of science is littered with theories that were scientific but turned out to be wrong; the scientific attitude reveals why even a failed theory can help us to understand what is special about science. McIntyre offers examples that illustrate both scientific success (a reduction in childbed fever in the nineteenth century) and failure (the flawed "discovery" of cold fusion in the twentieth century). He describes the transformation of medicine from a practice based largely on hunches into a science based on evidence; considers scientific fraud; examines the positions of ideology-driven denialists, pseudoscientists, and "skeptics" who reject scientific findings; and argues that social science, no less than natural science, should embrace the scientific attitude. McIntyre argues that the scientific attitude-the grounding of science in evidence-offers a uniquely powerful tool in the defense of science.

The UNESCO International Bioethics Committee is an international body that sets standards in the field of bioethics. This collection represents the contributions of the IBC to global bioethics. The IBC is a body of 36 independent experts that follows progress in the life sciences and its applications in order to ensure respect for human dignity and freedom. Currently, some of the topics of the IBC contributions have been discussed in the bioethics literature, mostly journal articles. However, this is a unique contribution by the scholars who developed these universal declarations and reports. The contributors have not only provided a scholarly up to date discussion of their research topics, but as members of the IBC they have also discussed specific practical challenges in the development of such international documents. This book will be suited to academics within bioethics, health care policy and international law.

This readable overview offers a public health framework for integrating medical and alternative care to improve health outcomes in patients with chronic illnesses. It details the promise, potential, and challenges of holistic services as patients seek diverse treatment options and health care systems address the demand for more affordable, accessible, and effective care. The book's integrative model describes the process in theory and practice, from cost and reimbursement issues and turf wars between providers to expanding on traditional concepts of illness and wellness. Learning objectives, case studies, discussion questions, and other helpful features make this a vital student text. The book's concentrated coverage: Introduces concepts of integrative health services. Applies integrative health concepts to public health areas, e.g., prevention. Contrasts integrative models of health with the traditional biomedical model. Outlines the scope of integrative health practice. Reviews implications for the public health workforce. Integrative Health Services benefits public health students, pre-med students, and those with an interest in health policy and health trends. Additionally, public health educators, practitioners, and scholars who may not be familiar with integrative health services and conflicts related to their increased use in health care will find it a helpful tool to quickly bring them up to date

Remediation in medical education is the act of facilitating a correction for trainees who started out on the journey toward becoming excellent physicians but have moved off course. This book offers an evidence-based and practical approach to the identification and remediation of medical trainees who are unable to perform to standards. As assessment of clinical competence and professionalism has become more sophisticated and ubiquitous, medical educators increasingly face the challenge of implementing effective and respectful means to work with trainees who do not yet meet expectations of the profession and society. Remediation in Medical Education: A Mid-Course Correction describes practical stepwise approaches to remediate struggling learners in fundamental medical competencies; discusses methods used to define competencies and the science underlying the fundamental shift in the delivery and assessment of medical education; explores themes that provide context for remediation, including professional identity formation and moral reasoning, verbal and nonverbal learning disabilities, attention deficit disorders in high-functioning individuals, diversity, and educational and psychiatric topics; and reviews system issues involved in remediation, including policy and leadership challenges and faculty development.

This volume presents a number of controversial cases of enforced medical treatment from around the globe, providing for the first time a common, biopolitcal framework for all of them. Bringing together all these real cases guarantees that a new, more complete understanding of the topic will be within grasp for readers unacquainted with the aspects involved in these cases. On the one hand, readers interested mainly in the legal and medical dimensions of cases like those considered will benefit from the explanation of the biopolitical framework within which each case develops. On the other hand, those focusing on only one of the situations presented here will find the parallels between the cases an interesting expansion of the complexity of the problem. Despite the book's ambitious goal, for those willing to use it as supplemental material or interested in only one of the cases, the chapters can function as self-standing pieces to be read separately. This volume will be a valuable tool for both academics and professionals. Bioethicists in both the analytic and continental traditions, will find the book interesting for not only the specific concepts and issues considered, but also for its constructive bridging of the two schools of thought. In addition to philosophers, the structure of this work will also appeal to lawyers, doctors, human rights activists, and anyone concerned in the most disparate way with real-life cases of enforced medical treatment.

This volume contributes to the growing literature on the morality of procreation and parenting. About half of the chapters take up questions about the morality of bringing children into existence. They discuss the following questions: Is it wrong to create human life? Is there a connection between the problem of evil and the morality of procreation? Could there be a duty to procreate? How do the environmental harms imposed by procreation affect its moral status? Given these costs, is the value of establishing genetic ties ever significant enough to render procreation morally permissible? And how should government respond to peoples' motives for procreating? The other half of the volume considers moral and political questions about adoption and parenting. One chapter considers whether the choice to become a parent can be rational. The two following chapters take up the regulation of adoption, focusing on whether the special burdens placed on adoptive parents, as compared to biological parents, can be morally justified. The book concludes by considering how we should conceive of adequacy standards in parenting and what resources we owe to children. This collection builds on existing literature by advancing new arguments and novel perspectives on existing debates. It also raises new issues deserving of our attention. As a whole it is sure to generate further philosophical debate on pressing and rich questions surrounding the bearing and rearing of children.

An accessible synthesis of ethical issues raised by artificial intelligence that moves beyond hype and nightmare scenarios to address concrete questions. Artificial intelligence powers Google's search engine, enables Facebook to target advertising, and allows Alexa and Siri to do their jobs. AI is also behind self-driving cars, predictive policing, and autonomous weapons that can kill without human intervention. These and other AI applications raise complex ethical issues that are the subject of ongoing debate. This volume in the MIT Press Essential Knowledge series offers an accessible synthesis of these issues. Written by a philosopher of technology, AI Ethics goes beyond the usual hype and nightmare scenarios to address concrete questions. Mark Coeckelbergh describes influential AI narratives, ranging from Frankenstein's monster to transhumanism and the technological singularity. He surveys relevant philosophical discussions: questions about the fundamental differences between humans and machines and debates over the moral status of AI. He explains the technology of AI, describing different approaches and focusing on machine learning and data science. He offers an overview of important ethical issues, including privacy concerns, responsibility and the delegation of decision making, transparency, and bias as it arises at all stages of data science processes. He also considers the future of work in an AI economy. Finally, he analyzes a range of policy proposals and discusses challenges for policymakers. He argues for ethical practices that embed values in design, translate democratic values into practices and include a vision of the good life and the good society.

'Clinical epidemiology' is now widely promoted and taught as a 'basic science' of Evidence-Based Medicine, of clinical EBM to be specific. This book, however, is mostly about that which Miettinen takes to be the necessary substitute for this now-so-fashionable subject - namely, Theory of Clinical Medicine together with its subordinate Theory of Clinical Research. The leit motif in all of this is Miettinen's perception of the need, and opportunity, to bring major improvements into clinical medicine in this Information Age, now that theoretical progress has made feasible the development of practice-guiding Expert Systems for it. Parts of this text constitute essential reading for whoever is expected, or otherwise inclined, to study - or teach - 'clinical epidemiology,' and the same is true of those who set policy for the education of future clinicians; but practically all of it is essential reading for future - and current - academics in the various disciplines of clinical medicine. After all, the text is the result of a concentrated effort, over a half-century no less, to really understand both clinical and community medicine and the research to advance the knowledge-base of these. Research epidemiologists, too, will find this text interesting and instructive.

While procreation is ubiquitous, attention to the ethical issues involved in creating children is relatively rare. In Debating Procreation, David Benatar and David Wasserman take opposing views on this important question. David Benatar argues for the anti-natalist view that it is always wrong to bring new people into existence. He argues that coming into existence is always a serious harm and that even if it were not always so, the risk of serious harm is sufficiently great to make procreation wrong. In addition to these "philanthropic" arguments, he advances the "misanthropic" one that because humans are so defective and cause vast amounts of harm, it is wrong to create more of them. David Wasserman defends procreation against the anti-natalist challenge. He outlines a variety of moderate pro-natalist positions, which all see procreation as often permissible but never required. After criticizing the main anti-natalist arguments, he reviews those pronatalist positions. He argues that constraints on procreation are best understood in terms of the role morality of prospective parents, considers different views of that role morality, and argues for one that imposes only limited constraints based on the well-being of the future child. He then argues that the expected good of a future child and of the parent-child relationship can provide a strong justification for procreation in the face of expected adversities without giving individuals any moral reason to procreate

This textbook presents epidemiology in a practical manner, contextualized with discussions of theory and ethics, so that students and professionals from all academic backgrounds may develop a deep appreciation for how to conduct and interpret epidemiological research. Readers will develop skills to: -Search for and appraise literature critically, -Develop important research questions, -Design and implement studies to address those questions, -Perform and interpret fundamental statistical estimations and tests, -Consider the ethical implications of all stages of research, -Report findings in publications, and -Advocate for change in the public health setting. Epidemiology is and will remain a discipline in motion, and this textbook aims at reflecting this dynamism and keeping pace with its momentum. This textbook is not only a classroom tool with high utility but also an essential reference and guide for those engaging in research involving human subjects.

The book provides an in-depth discussion on the human nature concept from different perspectives and from different disciplines, analyzing its use in the doping debate and researching its normative overtones. The relation between natural talent and enhanced abilities is scrutinized within a proper conceptual and theoretical framework: is doping to be seen as a factor of the athlete's dehumanization or is it a tool to fulfill his/her aspirations to go faster, higher and stronger? Which characteristics make sports such a peculiar subject of ethical discussion and what are the, both intrinsic and extrinsic, moral dangers and opportunities involved in athletic enhancement? This volume combines fundamental philosophical anthropological reflection with applied ethics and socio-cultural and empirical approaches. Furthermore guidelines will be presented to decision- and policy-makers on local, national and international levels. Zooming in on the intrinsic issue of what is valuable about our homo sapiens biological condition, this volume devotes only scant attention to the specific issue of natural talent and why such talent is appreciated so differently than biotechnological origins of ability. In addition, specific aspects of sports such as its competitive nature and its direct display of bodily prowess provide good reason to single out the issue of natural athletic talent for sustained ethical scrutiny.

This book looks at health policy through the lens of public versus private: population health versus the somatic, social, or emotional experiences of a patient. Rather than presenting policy/ethics as overly technical, this book takes a novel approach of framing public and private health in terms of political philosophy, ethics, and popular examples. Each chapter ties back to the general ethics or political literature as applicable, which are not customarily parts of the current public health curriculum. The author's work on the Orgcomplexity blog has touched on this subject by systemically exploring public policy issues, and the tone of this book mimics the blog with an extension of the arguments.

Medical ethics and the medical profession are inseparable, yet the formal teaching of medical ethics is a relatively new phenomenon. Furthermore, since the introduction of managed health care, with the physician becoming a 'health provider' and the patient a 'client', the whole concept of medical ethics has undergone a sea change. The contractual relationship between the provider and the client engenders caution and precaution, resulting in defensive medicine. This book both presents a succinct history of medical ethics and discusses a wide range of important ethical dilemmas in the provision of modern health care. A synopsis is provided of ethics through the ages and the role of ethics in the evolution of medicine. Principles and sources of medical ethics, as well as different religious and secular perspectives, are explained. Ethical concerns in relation to a variety of specific issues are then examined. These issues include, for example, human experimentation, stem cell research, assisted reproductive technologies, termination of pregnancy, rationing of health care, euthanasia, and quality of life issues. The author's many years of practicing medicine in different cultures and countries and his passion for religious works, philosophy, literature, poetry, history, and anthropology have informed and enriched the contents of this stimulating book.

In 2008 the youtube video documenting the emotional reunion between two men and Christian the Lion became a worldwide sensation. Key themes of the essays in Captured: the Animal within Culture are encapsulated in Christian's story: the implications of the physical and cultural capture of animals.

Anti-natalism is the provocative view that it is either always or almost always all-things-considered wrong to procreate. Philanthropic anti-natalist arguments say that procreation is always impermissible because of the harm done to individuals who are brought into existence. Misanthropic arguments, on the other hand, hold that procreation is usually impermissible given the harm that individuals will do once brought into existence. The main purpose of this short monograph is to demonstrate that David Benatar's misanthropic argument for anti-natalism ought to be endorsed by any version of African Communitarianism. Not only that, but there are also resources in the African philosophical tradition that offer unique support for the argument. Given the emphasis that indigenous African worldviews place on the importance of procreation and the immediate family unit this result is highly surprising. This book marks the first attempt to bring anti-natalism into conversation with contemporary African ethics.

The social practice of forming, shaping, expressing, contesting, and maintaining personal identities makes human interaction, and therefore society, possible. Our identities give us our sense of how we are supposed to act and how we may or must treat others, so how we hold each other in our identities is of crucial moral importance. To hold someone in her identity is to treat her according to the stories one uses to make sense of who she is. Done well, holding allows individuals to flourish personally and in their interactions with others; done poorly, it diminishes their self-respect and restricts their participation in social life. If the identity is to represent accurately the person who bears it, the tissue of stories that constitute it must continue to change as the person grows and changes. Here, good holding is a matter of retaining the stories that still depict the person but letting go of the ones that no longer do. The book begins with a puzzling instance of personhood, where the work of holding someone in her identity is tragically one-sided. It then traces this work of holding and letting go over the human life span, paying special attention to its implications for bioethics. A pregnant woman starts to call her fetus into personhood. Children develop their moral agency as they learn to hold themselves and others in their identities. Ordinary adults hold and let go, sometimes well and sometimes badly. People bearing damaged or liminal identities leave others uncertain how to hold and what to let go. Identities are called into question at the end of life, and persist after the person has died. In all, the book offers a glimpse into a fascinating moral terrain that is ripe for philosophical exploration.

Akira Akabayashi presents the first book to explore the conversation on bioethics that is taking place between scholars and practitioners from the East and West: the first book in the discipline of bioethics for the globalized world of the future. An international team of experts address emerging issues in bioethics, focus on new developments and their potential for change, and set the agenda for the future. Most studies in bioethics advocating East-West dialogue have either attempted cross-cultural comparisons or have proposed Eastern philosophical paradigms to counter Western ideas. The tacit premise of previous work on the East-West dialogue is therefore a strain of relativism. Simply maintaining a respectful distance from other cultures is no longer sufficient in this era of globalization. The time has come for active engagement among different cultural perspectives. The Future of Bioethics initiates discussion on bioethical issues that arise from new medical technologies such as regenerative medicine, enhancement, research ethics, and synthetic biology, and goes on to address challenging dilemmas that result from the globalization of social change, such as transplantation tourism, public health ethics, care in the aging society, and professionalism. The volume presents original work by leading researchers in the field, alongside that of promising new scholars; as such, it establishes not only a cross-cultural dialogue, but dialogue between researchers of different generations. The book is divided into two parts-the first on the progress of biomedical technologies and ethics, and the second on globalization and bioethics. Each part contains four sections on different topics, which feature a lead essay followed by a set of commentaries and further discussion.

In this edited volume, scientists from different disciplines discuss modern biotechnological processes and a knowledge-based bioeconomy. The authors base their arguments on ecological, economic, legal, social and ethical aspects. Moreover, they explore the opportunities, risks, and challenges of bioeconomic concepts and biotechnologies in many subject areas. The chapters consider land use, nature and environment, nutrition, technology and governance, energy, economy, law and regulation, as well as ethics. A special focus should be on new technologies and how they can be used, without compromising the ambitious goal of creating a more sustainable, but also fair world. To do justice to this broad array of topics, the editors frame all topics in overarching introductions and close the volume with final conclusions. Thereby this volume offers data and critical thoughts for any member of a Bioeconomy - be it from academia, the industry or public regulation.

Living and Dying Well takes an informed, interdisciplinary approach to the problems, data, theory, and procedures that a just society must consider when establishing policies regarding human life and death. Leading psychologist Lewis Petrinovich expands on the controversial arguments developed in his earlier work, Human Evolution, Reproduction, and Morality, and considers such contemporary issues as: the morality of human genetic screening and of the Human Genome Project; organ transplants; the allowance of suicide and euthanasia; and physicians assisting in the dying process.

In ALLOCATING HEALTH CARE RESOURCES, leading authorities and researchers expose the basic philosophical, ethical, and economic issues underlying the current health care debate. The contributors wrestle with such complicated issues as whether it is ethical to ration health care, the morality of the worldwide bias against children in allocating health care resources, whether sin taxes can be defended morally, and how to achieve a just health care system. The book also includes an insightful analysis of the Clinton health care reform plan.
ALLOCATING HEALTH CARE RESOURCES will be of interest to philosophers, health policy experts, medical ethicists, health professionals, and concerned citizens. It serves to clarify and illuminate the logic and rhetoric of health care reform, and so to help us all achieve a fair and equitable distribution of these precious resources.