Human beings seek to transcend limits. This is part of our potential greatness, since it is how we can realize what is best in our humanity. However, the limit-transcending feature of human life is also part of our potential downfall, as it can lead to dehumanization and failure to attain important human goods and to prevent human evils. Exploring the place of limits within a well-lived human life this work develops and defends an original account of limiting virtues, which are concerned with recognizing proper limits in human life. The limiting virtues that are the focus are humility, reverence, moderation, contentment, neighborliness, and loyalty, and they are explored in relation to four kinds of limits: existential limits, moral limits, political limits, and economic limits. These virtues have been underexplored in discussions about virtue ethics, and when they have been explored it has not been with regard to the general issue of the place of limits within a well-lived human life. The account of the limiting virtues provided here, however, is intended as a counter to other prominent approaches to ethics: namely, autonomy-centered approaches and consequentialist (or maximizing) approaches. This account is also used to address a number of important contemporary issues such as genetic engineering, distributive justice, cosmopolitanism vs. patriotism, and the ethical status of growth-based economics.

This book questions the notions of person, personality, dignity, and other connected notions such as (informed) consent, and discusses new perspectives on categories that allow ethical debates in medicine to overcome morals and ordinary religious schemes. The book states that one has to be careful when thinking about situations in terms of notions and principles that have been obtained in similar situations. Though this book is mostly philosophical, it is also of great practical interest to healthcare givers. It warns caregivers not to rely too much on notions such as person, autonomy, and consent, which are supposedly firm but can be proven to be unreliable in spite of appearances. Furthermore, this work warns against a narrow anthropologisation of ethics which would make technophobian positions unavoidable. On the contrary, this book is open to robotics and offers - among other things - a sustained exploration of the notion of intimacy.

This book brings together a number of essays that are optimistic about the ways certain neuroscientific insights might advance philosophical ethics, and other essays that are more circumspect about the relevance of neuroscience to philosophical ethics. As a whole, the essays form a self-reflective body of work that simultaneously seeks to derive normative ethical implications from neuroscience, and to question whether and how that may be possible at all. In doing so, the collection brings together psychology, neuroscience, philosophy of mind, ethics, and philosophy of science. Neuroscience seeks to understand the biological systems that guide human behavior and cognition. Normative ethics, on the other hand, seeks to understand the system of abstract moral principles dictating how people ought to behave. By studying how the human brain makes moral judgments, can philosophers learn anything about the nature of morality itself? A growing number of researchers believe that neuroscience can, indeed, provide insights into the questions of philosophical ethics. However, even these advocates acknowledge that the path from neuroscientific is to normative ethical ought can be quite fraught.

This book observes the idea of race as a false representation for the cause of disease. Race-based medicine, an emerging field in pharmacology, aims to create a specialty market based on racial groups. Within this market, the drug BiDil set a precedent in this area of medicine targeting African Americans as its first racial group. Consequently, selecting African Americans as a "starter group" led to ethical questions regarding the motive behind race-based medicine within the context of the larger treatment of blacks in American medical history. This book therefore links medicine and American eugenics, examines race-based medicine's influence on the perception of the black body, traces the influence of BiDil's approval on the resurgence of race-based medicine, and assesses the black church's response to race-based medicine using black liberation theology as a means to social justice.

This book addresses the complexity of talking about normativity in bioethics within the context of contemporary multicultural and multi-religious society. It offers original contributions by specialists in bioethics exploring new ways of understanding normativity in bioethics. In bioethical publications and debates, the concept of normativity is often used without consideration of the difficulties surrounding it, whereas there are many competing claims for normativity within bioethics. Examples of such competing normative bioethical discourses can be perceived in variations and differences in bioethical arguments within individual religions, and the opposition between bioethical arguments from specific religions and arguments from bioethicists who do not claim religious allegiance. We also cannot merely assume that a Western understanding of normative bioethics will be unproblematic in bioethics in non-Western cultures and religions. Through an analysis of normativity in Christian, Hindu, Buddhist, Islamic, and Jewish bioethics, the book creates awareness of the complexity of normativity in bioethics. The book also covers normative bioethics outside an explicitly religiously committed context, and specific attention is paid to bioethics as an interdisciplinary endeavor. It reveals how normativity relates to empirical and global bioethics, which challenges it faces in bioethics in secular pluralistic society, and how to overcome these. By doing that, this book fills an important gap in bioethics literature.

This book offers easy access to the everyday ethics problems that occur in the medical care of children. It contains practical guidance on how physicians and other healthcare practitioners may manage both straightforward and complex ethics problems. The book provides a readable and comprehensive introduction to ethics issues for beginners and is also extremely valuable to experienced practitioners.This work covers important "classical" ethical issues such as privacy, confidentiality, truth telling, and discusses the elements of the relationships that might exist between parents and healthcare providers. However, the book also provides a resource for new and emerging areas of bioethics. These include issues arising in the new population of children who are beginning to survive the neonatal and infant periods with a multitude of problems - "children with medical complexity". Finally, it also includes a section on the advantages and pitfalls of social media use.

This Open Access volume provides in-depth analysis of the wide range of ethical issues associated with drug-resistant infectious diseases. Antimicrobial resistance (AMR) is widely recognized to be one of the greatest threats to global public health in coming decades; and it has thus become a major topic of discussion among leading bioethicists and scholars from related disciplines including economics, epidemiology, law, and political theory. Topics covered in this volume include responsible use of antimicrobials; control of multi-resistant hospital-acquired infections; privacy and data collection; antibiotic use in childhood and at the end of life; agricultural and veterinary sources of resistance; resistant HIV, tuberculosis, and malaria; mandatory treatment; and trade-offs between current and future generations. As the first book focused on ethical issues associated with drug resistance, it makes a timely contribution to debates regarding practice and policy that are of crucial importance to global public health in the 21st century.

This book discusses recent brain research and the potentially dangerous dual-use applications of the findings of these research projects. The book is divided into three sections: Part I examines the rise in dual-use concerns within various state's chemical and biological non-proliferation regime's during this century, as well as the rapid technologically driven advances in neuroscience and the associated possible misuse considerations in the same period. Part II reviews the brain research projects in the EU, USA, Japan, China and several other countries with regard to their objectives, achievements and measures to deal with the problem of dual-use. Part III assesses the extent to which the results of this civil neuroscience work, which is intended to be benign, are being, and could be protected against future hostile applications in the development of novel chemical and biological weapons.

Fifteen philosophers, social scientists, and academic lawyers assess various aspects of bioethics. Some detail its development and challenge the field's basic assumptions. Others consider bioethics's role in contemporary society and examine it in policy administration as well as in its interaction with other branches of philosophical inquiry. Chapters also focus on specific issues, including the responsibilities of researchers to subjects in clinical trials; the proper criteria for determining when a living organism has died; the allocation of scarce, life-saving medical resources; and the subsidization of pharmaceutical products for those who may be deprived of the benefits of modern medicine.

This is the second edition of a highly successful and well-received textbook on the responsible conduct of biomedical and health science research. It is aimed at faculty and graduate students in health science and biomedical science programs. In addition, those on National Institute of Health research grants, administrators at universities, and academic health centers will find it a useful resource. The major changes include new chapters providing overviews of each topic, several new published articles added to the readings, revised case studies as well as further readings and web addresses.

Onora O'Neill suggests that the conceptions of individual autonomy (so widely relied on in bioethics) are philosophically and ethically inadequate; they undermine rather than support relationships based on trust. Her arguments are illustrated with issues raised by such practices as the use of genetic information by the police, research using human tissues, new reproductive technologies, and media practices for reporting on medicine, science and technology. The study appeals to a wide range of readers in ethics, bioethics and related disciplines.

Ethical Futures and Global Science Fiction explores the ethical concerns and dimensions of representations of the future of global science fiction, focusing on the issues that dominate utopian, dystopian and science fiction literature. The essays examine recent visions of the future in science fiction and re-examine earlier texts through contemporary lenses. Across fourteen chapters, the collection considers authors from Algeria, Australia, Canada, China, Egypt, France, Germany, Haiti, India, Jamaica, Macedonia, Mexico, Russia, South Africa, the UK and USA. The volume delves into a range of ethical questions of immediate contemporary relevance, including environmental ethics, postcolonial ethics, social justice, animal ethics and the ethics of alterity.

This book provides a comprehensive overview of the basic and advanced metabolic engineering technologies used to generate natural metabolites and industrially important biomolecules. Metabolic engineering has the potential to produce large quantities of valuable biomolecules in a renewable and sustainable manner by extending or modifying biosynthetic pathways in a wide range of organisms. It has been successfully used to produce chemicals, drugs, enzymes, amino acids, antibiotics, biofuels, and industrially important pharmaceuticals. The book comprehensively reviews the various metabolites detection, extraction and biosensors and the metabolic engineering of microbial strains for the production of industrially useful enzymes, proteins, organic acids, vitamins and antibiotics, therapeutics, chemicals, and biofuels. It also discusses various genetic engineering and synthetic biology tools for metabolic engineering. In closing, the book discusses ethical, patenting and regulatory issues in the metabolic engineering of microbes. This book is a valuable source not only for beginners in metabolic engineering, but also students, researchers, biotechnology and metabolic engineering based company.

This book engages in a critical discussion on how to respect and promote patients' autonomy in difficult cases such as palliative care and end-of-life decisions. These cases pose specific epistemic, normative, and practical problems, and the book elucidates the connection between the practical implications of the theoretical debate on respecting autonomy, on the one hand, and specific questions and challenges that arise in medical practice, on the other hand. Given that the idea of personal autonomy includes the notion of authenticity as one of its core components, the book explicitly includes discussions on underlying theories of the self. In doing so, it brings together original contributions and novel insights for "applied" scenarios based on interdisciplinary collaboration between German and Serbian scholars from philosophy, sociology, and law. It is of benefit to anyone cherishing autonomy in medical ethics and medical practice.

Little more than a decade ago the term "genetic engineering" was hardly known outside research laboratories. Today it regularly makes headlines. Those in favor of genetic engineering--and those against it--tell us that it has the potential to change our lives perhaps more than any other scientific or technological advance. But what are the likely consequences of genetic engineering? Is it ethically acceptable? Should we be trying to improve on nature? In Improving Nature?, the authors, a biologist and a moral philosopher, examine the implications of genetic engineering in every aspect of our lives. The underlying science is clearly explained and the moral and ethical considerations are fully disussed, resulting in a wide-ranging, balanced overview of a controversial subject. Michael Jonathan Reiss, a biologist, is Professor of Science Education and Head of Science & Technology, University of London Institute of Education. He is the author of Understanding Science Lessons (Open University Press, 2000). Roger Straughan is Reader in Education at the University of Reading. He is the author of Beliefs, Behaviour and Education (Cassell Academic, 1989). Previous paperback edition (1996) 0-521-63754-6

Are scientists playing God? Are the artificial reproductive technologies helpful or hazardous? Should human embryos ever be used for research? How do we cope with people who are mentally ill? Is someone in a persistent vegetative state still alive? How should we treat those with dementia? Questions like these are all around us. They affect ordinary people, who often feel ill equipped to respond to them. No one seems to have adequate answers. Do Christians have answers?In this book, aimed at the general reader, Professor Gareth Jones considers a range of topics ranging all the way from early embryos through to old age. While he concentrates on bioethical issues in the West, he is deeply concerned at the huge disparity in mortality and quality of life in different parts of the world. He also asks how Christians can best contribute to the discussion of bioethical issues within pluralist societies.Professor Jones is never afraid to face unpalatable issues head-on, and provide ways forward. He invites people to enter debates that we avoid at our peril. The book deals from beginning of life, early life, middle life and end of life issues.

This is the Second Edition of a well-received book that reflects a fresh, integrated coverage of the concepts and scientific measurement of stress and welfare of animals including humans. This book explains the basic biological principles of coping with many forms of adversity. The major part of this work is devoted to explaining scientifically usable concepts in stress and welfare. A wide range of welfare indicators are highlighted in detail with examples being drawn from man and other species. The necessity for combining information from disciplines is emphasized with a one-health, one-welfare approach. This information forms the basis for a synthesis of new ideas. Among the issues covered are: - How brain and body systems regulate using feelings, physiological responses, behaviour and responses to pathology - Limits to adaptation - Assessing positive and negative welfare during both short-term and long-term situations - Ethical problems and suggested solutions A proper assessment of animal welfare is essential to take informed decisions about what is morally acceptable in terms of practice and in the development of a more effective legislation. This work encapsulates a very wide body of literature on scientific aspects of animal welfare and will thus prove a valuable asset for animal welfare scientists, psychologists, students and teachers of all forms of biology, behaviour, medicine, veterinary medicine and animal usage.

This book articulates an African conception of dignity in light of the salient axiological category of personhood in African cultures. The idea of personhood embodies a moral system for evaluating human lives exuding with virtue or ones that are morally excellent. This book argues that this idea of personhood embodies an under-explored conception of dignity, which accounts for it in terms of our capacity for the virtue of sympathy. It then proceeds to apply this personhood-based conception of dignity to bioethical questions, specifically, those of abortion and euthanasia. Regarding abortion, it concludes that it is impermissible since foetuses possess partial moral status. Regarding euthanasia, it argues that it is permissible for reasons revolving around avoiding the reversing of personhood. It also, though, minimally, touches on the questions regarding the mentally disabled and animals, to which it assigns lower moral status.

This book provides a bridge between the theory to practice gap in contemporary health care ethics. It explores the messiness of everyday ethical issues and validates the potential impacts on health care professionals as wounded healers who regularly experience close proximity to suffering and pain. This book speaks to why ethics matters on a personal level and how moral distress experiences can be leveraged instead of hidden. The book offers contributions to both scholarship and the profession. Nurses, physicians, social workers, allied health care professionals, as well as academics and students will benefit from this book.

In this book, the author argues that no current philosophical theory of evidence in clinical medical science is adequate. None can accurately explain the way evidence is gathered and used to confirm hypotheses. To correct this, he proposes a new approach called the weight of evidence account. This innovative method supplies a satisfactory explanation and rationale for the "hierarchical pyramid" of evidence-based medicine, with randomized clinical trials and their derivatives, meta-analyses, and systematic reviews of randomized clinical trials at the top and case reports, case series, expert opinion, and the like at the bottom. The author illustrates the development of various "levels" of evidence by considering the evolution of less invasive surgical treatments for early breast cancer. He shows that the weight of evidence account explains the notion of levels of evidence and other efforts to rank them. In addition, he presents a defense of randomization as a method to maximize accuracy in the conduct of clinical trials. The title also considers ethical issues surrounding experimentation with medical therapies in human subjects. It illustrates and discusses these issues in studies of respiratory therapies in neonates and treatment for certain cancers in adults. The author shows that in many cases sufficient evidence can be accrued to warrant generally accepted new therapies without the need for evidence derived from randomized clinical trials.

This book provides a comprehensive description and ethical analysis of one of the most challenging areas: international health research. Furthermore, it provides a vivid portrait of the current situation of global governance for health research and its main challenges and suggests a comprehensive and universal ethical framework based on the existing theories and frameworks. This work is a must-read for all the students, scholars, professionals, activists, and policy-makers who are involved or interested in the global health research enterprise and its governance and ethics.

This book offers an innovative approach to moral enhancement. We, as humans, have a moral duty to be as good as we can be. Hence, moral bio-enhancement (MBE), if effective and safe, is our moral duty. However, it has to be voluntary because if it is made compulsory, human freedom (of the will) would be curtailed. As freedom (of the will) is an essential component of humanness, compulsory MBE would infringe upon our humanness. An essential question is; what will motivate humans to subject themselves voluntarily to MBE?The book argues - and supports by using empirical/experimental evidence - that morality and happiness operate in a circularly supportive relationship that applies to most humans most of the time: the better they are, the happier they will be; the happier they are, the better they will be. Hence, the grounding rationale for MBE ought not to be the prevention of "ultimate harm" based on compulsory MBE (as argued by Persson and Savulescu), but human happiness based on voluntary MBE. The primary objective of the book is to provide the readers with an original view on moral enhancement, whilst proposing a novel conception of moral enhancement that is informed by new biotechnological developments.

This book deals with good, evil, happiness and morally enhanced post-humans. It offers a succinct historical elaboration of philosophical stances towards morality and happiness, focusing on Kant's ideas in particular. Human augmented ethical maturity in a futuristic version of Kant's Ethical Commonwealth implies, among else, voluntary moral bio-enhancement (VMBE); consequently, more happiness - as morality and happiness are in a circularly supportive relationship; ultimate morality (UM). UM is in its own way a universal morality. In line with the contention that Kant's vision of the (not immediate but more distant) future of humanity is one of a cosmopolitan moral order in which humans act virtuously in the broadest possible community, that is, humanity, it is justified to conclude that successful VMBE is conducive to Kant's vision. In this context the book is of great interest to a broad audience, such as those interested in VMBE and novel conceptions of morality, and those with an interest in the historical development of morality and happiness, in philosophy (specifically, ethics) and in post-humanity.

This book examines the ethics of end of life care, focusing on the kinds of decisions that are commonly made in clinical practice. Specific attention is paid to the intensification of treatment for terminal symptoms, particularly pain relief, and the withdrawal and withholding of care, particularly life-saving or life-prolonging medical care. The book is structured into three sections. The first section contains essays examining end of life care from the perspective of moral theory and theology. The second sets out various conceptual terms and distinctions relevant to decision-making at the end of life. The third section contains chapters that focus on substantive ethical issues. This format not only provides for a comprehensive analysis of the ethical issues that arise in the context of end of life care but allows readers to effectively trace the philosophical, theological and conceptual underpinnings that inform their specific interests. This work will be of interest to scholars working in the area as well as clinicians, specialists and healthcare professionals who encounter these issues in the course of their practice.

This book examines the controversial and repercussive contention that an objective of the law should be to promote personal morality - to make people ethically better. It surveys a number of domains, including criminal law, tort law, contract law, family law, and medical law (particularly the realm of moral enhancement technologies) asking for each: (a) Does the existing law seek to promote personal morality? (b) If so, what is the account of morality promoted, and what is the substantive content? (c) Does it work? and (d) Is this a legitimate objective?