This book examines the dependence of transhumanist arguments on the credibility of the narratives of meaning in which they are embedded. By taking the key ideas from transhumanist philosophy - the desirability of human self-design and immortality, the elimination of all suffering and the expansion of human autonomy - Michael Hauskeller explores these narratives and the understanding of human nature that informs them. Particular attention is paid to the theory of transhumanism as a form of utopia, stories of human nature, the increasing integration of the radical human enhancement project into the cultural mainstream, and the drive to upgrade from flesh to machine.

An accessible synthesis of ethical issues raised by artificial intelligence that moves beyond hype and nightmare scenarios to address concrete questions. Artificial intelligence powers Google's search engine, enables Facebook to target advertising, and allows Alexa and Siri to do their jobs. AI is also behind self-driving cars, predictive policing, and autonomous weapons that can kill without human intervention. These and other AI applications raise complex ethical issues that are the subject of ongoing debate. This volume in the MIT Press Essential Knowledge series offers an accessible synthesis of these issues. Written by a philosopher of technology, AI Ethics goes beyond the usual hype and nightmare scenarios to address concrete questions. Mark Coeckelbergh describes influential AI narratives, ranging from Frankenstein's monster to transhumanism and the technological singularity. He surveys relevant philosophical discussions: questions about the fundamental differences between humans and machines and debates over the moral status of AI. He explains the technology of AI, describing different approaches and focusing on machine learning and data science. He offers an overview of important ethical issues, including privacy concerns, responsibility and the delegation of decision making, transparency, and bias as it arises at all stages of data science processes. He also considers the future of work in an AI economy. Finally, he analyzes a range of policy proposals and discusses challenges for policymakers. He argues for ethical practices that embed values in design, translate democratic values into practices and include a vision of the good life and the good society.

Conscience in Reproductive Health Care responds to the growing worldwide trend of health care professionals conscientiously refusing to provide abortions and similar reproductive health services in countries where these services are legal and professionally accepted. Carolyn McLeod argues that conscientious objectors in health care should prioritize the interests of patients in receiving care over their own interest in acting on their conscience. She defends this "prioritizing approach" to conscientious objection over the more popular "compromise approach" without downplaying the importance of health care professionals having a conscience or the moral complexity of their conscientious refusals. McLeod's central argument is that health care professionals who are gatekeepers of services such as abortions are fiduciaries for their patients and for the public they are licensed to serve. As such, they owe a duty of loyalty to these beneficiaries and should give primacy to their beneficiaries' interests in accessing care. This conclusion is informed by what McLeod believes is morally at stake for the main parties to the conflicts generated by conscientious refusals: the objector and the patient. What is at stake, according to McLeod, depends on the relevant socio-political context, but typically includes the objector's integrity and the patient's interest in avoiding harm.

Scientific medicine in Miettinen's conception of it is very different from the two ideas about it that come to eminence in the 20th century. To him, medicine is scientific to the extent that it has a rational theoretical framework and a knowledge-base from medical science. He delineates the nature of that theoretical framework and of the research to develop the requisite knowledge for application in such a framework. The knowledge ultimately needed is about diagnostic, etiognostic, and prognostic probabilities, and it necessarily is to be codified in the form of probability functions, embedded in practice-guiding expert systems. In these terms, today's medicine still is mostly pre-scientific, and major innovations are needed within and around medicine for healthcare to get to be in tune with reasonable expectations about it in this Information Age. Thus, while the leading cause of litigation for medical malpractice in the U.S. is failure to expeditiously and correctly diagnose the probability of myocardial infarction in a hospital's emergency room, this book shows that a typical modern textbook of cardiology, just as one of medicine at large, imparts no knowledge about the diagnostic probabilities needed in this, and that the prevailing type of diagnostic research will not produce the requisite knowledge. If the diagnostic pursuits in an ER would be guided by an emergency-room diagnostic expert system, this would guarantee expert diagnoses by all ER doctors. Academic leaders of medicine and medical researchers concerned to advance the knowledge-base of medicine will find a wealth of stimulus for thinking about the deficiencies of the prevailing knowledge culture in and surrounding medicine, and about the directions of the needed progress toward genuinely scientific medicine.

In this thought-provoking and innovative book, Kendra Coulter examines the diversity of work done with, by, and for animals. Interweaving human-animal studies, labor theories and research, and feminist political economy, Coulter develops a unique analysis of the accomplishments, complexities, problems, and possibilities of multispecies and interspecies labor. She fosters a nuanced, multi-faceted approach to labor that takes human and animal well-being seriously, and that challenges readers to not only think deeply and differently about animals and work, but to reflect on the potential for interspecies solidarity. The result is an engaging, expansive, and path-making text.

Imagine that you are an environmentalist who passionately believes that it is wrong to drill for oil in the Arctic National Wildlife Refuge. How do you convince someone that a decision to drill is wrong? Debates about the environment and how humans ought to treat it have gone on for decades, yet arguments in favor of preserving biodiversity often lack empirical substance or are philosophically naive, making them far less effective than they could be. This book critically examines arguments that are commonly offered in support of biodiversity conservation. The authors adopt a skeptical viewpoint to thoroughly test the strength of each argument and, by demonstrating how scientific evidence can be integrated with philosophical reasoning, they help environmentalists to better engage with public debate and judiciously inform public policy. This interdisciplinary and accessible book is essential reading for anyone who engages in discussions about the value of biodiversity conservation.

This volume addresses the proper character of patient informed consent to medical treatment and clinical research. The goal is critically to explore the current individually oriented approach to informed consent which grew out of the dominant bioethics movement that arose in the United States in the 1970s. In contrast to that individually oriented approach, this volume explores the importance of family-oriented approaches to informed consent for medical treatment and clinical research. It draws on both East Asian moral resources as well as a critical response to the ways in which the practice of informed consent has developed in the United States

Nanobiotechnology is a fast developing field of research and application in many domains such as in medicine, pharmacy, cosmetics and agro-industry. The book addresses the lastest fundamental results on nanotoxicology and nanoethics, and the enormous range of potential applications in the fields of medical diagnostics, nanomedicine, and food and water administration. Nanoscale objects have properties leading to specific kinds of behaviour, sometimes exacerbating their chemical reactivity, physical behaviour, or potential to penetrate deeply within living organisms. Hence it is important to ensure the responsible and safe development of nanomaterials and nanotechnologies. This fourth volume in the Nanoscience series should make its mark, by presenting the state of the art in the fields of nanotoxicology and nanoethics. This is the first book to combine both scientific knowledge and ethical and social recommendations. It also presents specific policies on nanotechnologies set up by national and international authorities. This book is of interest to engineers, researchers, and graduate students.

At the time of the first edition of Principles of Cancer Biotherapy in 1987, this book represented the first comprehensive textbook on biological therapy. In 1991, when the second edition was published, there was still some doubt on the part of many oncologists and cancer researchers as to the therapeutic value of these new approaches. By 2003 and the fourth edition, it was generally agreed that biopharmaceuticals were producing major opportunities for new cancer therapies. Cancer biotherapy has now truly matured into the fourth modality of cancer treatment. This fifth revised edition describes the tremendous progress that has been made in recent years using biologicals in cancer treatment. This book summarizes an evolving science and a rapidly changing medical practice in biotherapy. In this new millennium, it is now possible to envision a much more diversified system of cancer research and treatment that will afford greater opportunities for a patient's personalized cancer treatment. This was first envisioned in the 1987 initial edition of this textbook and is now a "new" and popular approach to cancer treatment. Some forms of cancer biotherapy use the strategy of tumor stabilization and control through continued biological therapy, akin to the use of insulin in the treatment of diabetes. This textbook illustrates new methods of thinking and new strategies for control of cancer. It is always difficult to move from past dogma to future opportunity, but this fifth edition of Principles of Cancer Biotherapy illustrates why it is so important to the patients for researchers and clinicians to explore and quickly apply these new opportunities in cancer biotherapy.

This thought-provoking treatise argues that current human fertility rates are fueling a public health crisis that is at once local and global. Its analysis and data summarize the ecological costs of having children, presenting ethical dilemmas for prospective parents in an era of competition for scarce resources, huge disparities of wealth and poverty, and unsustainable practices putting irreparable stress on the planet. Questions of individual responsibility and integrity as well as personal moral and procreative issues are examined carefully against larger and more long-range concerns. The author's assertion that even modest efforts toward reducing global fertility rates would help curb carbon emissions, slow rising global temperatures, and forestall large-scale climate disaster is well reasoned and more than plausible. Among the topics covered: * The multiplier effect: food, water, energy, and climate. * The role of population in mitigating climate change. * The carbon legacy of procreation. * Obligations to our possible children. * Rights, what is right, and the right to do wrong. * The moral burden to have small families. Toward a Small Family Ethic sounds a clarion call for bioethics students and working bioethicists. This brief, thought-rich volume steers readers toward challenges that need to be met, and consequences that will need to be addressed if they are not.

This work sets the stage regarding debates about paternalism and health care for years to come. The anthology is organized around four parts: i) The concept of paternalism and theoretical issues regarding the idea of anti-paternalism, ii) strategies for justifying different forms of paternalism, iii) paternalism in psychiatry and psychotherapy, iv) paternalism and public health, and v) paternalism and reproductive medicine. Medical paternalism was arguably one of the main drivers of debates in medical ethics and has led to a wide acknowledgement of the value of patient autonomy. However, more recent developments in health care, such as the increasing significance of public health measures and the commercialization of medical services, have led to new social circumstances and hence to the need to rethink issues regarding paternalism. This work provides an invaluable source for many scholars and practitioners, since it deals in new and original ways with one of the main and oldest issue in health care ethics.

With the advance of biomedicine, certain individuals and groups are vulnerable because of their incapacities to defend themselves. The International Bioethics Committee as a UNESCO working group has for the last several years dedicated to deepen this principle of human vulnerability and personal integrity. This book serves to supplement this effort with a religious perspective given a great number of the world’s population is affiliated with some religious traditions. While there is diversity within each of these traditions, all of them carry in them the mission to protect the weak, the underprivileged, and the poor. Thus, here presented is a collection of papers written by bioethics experts from six major world religions—Buddhism, Christianity, Confucianism, Hinduism, Islam and Judaism—who were gathered to discuss the meaning and implications of the principle of vulnerability in their respective traditions.        

An argument that what makes science distinctive is its emphasis on evidence and scientists' willingness to change theories on the basis of new evidence. Attacks on science have become commonplace. Claims that climate change isn't settled science, that evolution is "only a theory," and that scientists are conspiring to keep the truth about vaccines from the public are staples of some politicians' rhetorical repertoire. Defenders of science often point to its discoveries (penicillin! relativity!) without explaining exactly why scientific claims are superior. In this book, Lee McIntyre argues that what distinguishes science from its rivals is what he calls "the scientific attitude"-caring about evidence and being willing to change theories on the basis of new evidence. The history of science is littered with theories that were scientific but turned out to be wrong; the scientific attitude reveals why even a failed theory can help us to understand what is special about science. McIntyre offers examples that illustrate both scientific success (a reduction in childbed fever in the nineteenth century) and failure (the flawed "discovery" of cold fusion in the twentieth century). He describes the transformation of medicine from a practice based largely on hunches into a science based on evidence; considers scientific fraud; examines the positions of ideology-driven denialists, pseudoscientists, and "skeptics" who reject scientific findings; and argues that social science, no less than natural science, should embrace the scientific attitude. McIntyre argues that the scientific attitude-the grounding of science in evidence-offers a uniquely powerful tool in the defense of science.

The UNESCO International Bioethics Committee is an international body that sets standards in the field of bioethics. This collection represents the contributions of the IBC to global bioethics. The IBC is a body of 36 independent experts that follows progress in the life sciences and its applications in order to ensure respect for human dignity and freedom. Currently, some of the topics of the IBC contributions have been discussed in the bioethics literature, mostly journal articles. However, this is a unique contribution by the scholars who developed these universal declarations and reports. The contributors have not only provided a scholarly up to date discussion of their research topics, but as members of the IBC they have also discussed specific practical challenges in the development of such international documents. This book will be suited to academics within bioethics, health care policy and international law.

This readable overview offers a public health framework for integrating medical and alternative care to improve health outcomes in patients with chronic illnesses. It details the promise, potential, and challenges of holistic services as patients seek diverse treatment options and health care systems address the demand for more affordable, accessible, and effective care. The book's integrative model describes the process in theory and practice, from cost and reimbursement issues and turf wars between providers to expanding on traditional concepts of illness and wellness. Learning objectives, case studies, discussion questions, and other helpful features make this a vital student text. The book's concentrated coverage: Introduces concepts of integrative health services. Applies integrative health concepts to public health areas, e.g., prevention. Contrasts integrative models of health with the traditional biomedical model. Outlines the scope of integrative health practice. Reviews implications for the public health workforce. Integrative Health Services benefits public health students, pre-med students, and those with an interest in health policy and health trends. Additionally, public health educators, practitioners, and scholars who may not be familiar with integrative health services and conflicts related to their increased use in health care will find it a helpful tool to quickly bring them up to date

Remediation in medical education is the act of facilitating a correction for trainees who started out on the journey toward becoming excellent physicians but have moved off course. This book offers an evidence-based and practical approach to the identification and remediation of medical trainees who are unable to perform to standards. As assessment of clinical competence and professionalism has become more sophisticated and ubiquitous, medical educators increasingly face the challenge of implementing effective and respectful means to work with trainees who do not yet meet expectations of the profession and society. Remediation in Medical Education: A Mid-Course Correction describes practical stepwise approaches to remediate struggling learners in fundamental medical competencies; discusses methods used to define competencies and the science underlying the fundamental shift in the delivery and assessment of medical education; explores themes that provide context for remediation, including professional identity formation and moral reasoning, verbal and nonverbal learning disabilities, attention deficit disorders in high-functioning individuals, diversity, and educational and psychiatric topics; and reviews system issues involved in remediation, including policy and leadership challenges and faculty development.

Neuroscientists are mining nucleic acids, blood, saliva, and brain images in hopes of uncovering biomarkers that could help estimate risk of brain disorders like psychosis and dementia; though the science of bioprediction is young, its prospects are unearthing controversy about how bioprediction should enter hospitals, courtrooms, or state houses. While medicine, law, and policy have established protocols for how presence of disorders should change what we owe each other or who we blame, they have no stock answers for the probabilities that bioprediction offers. The Neuroethics of Biomarkers observes, however, that for many disorders, what we really care about is not their presence per se, but certain risks that they carry. The current reliance of moral and legal structures on a categorical concept of disorder (sick verses well), therefore, obscures difficult questions about what types and magnitudes of probabilities matter. Baum argues that progress in the neuroethics of biomarkers requires the rejection of the binary concept of disorder in favor of a probabilistic one based on biological variation with risk of harm, which Baum names a "Probability Dysfunction. " This risk-reorientation clarifies practical ethical issues surrounding the definition of mental disorder in the DSM-5 and the nosology of conditions defined by risk of psychosis and dementia. Baum also challenges the principle that the acceptability of bioprediction should depend primarily on whether it is medically useful by arguing that biomarkers can also be morally useful through enabling moral agency, better assessment of legal responsibility, and fairer distributive justice. The Neuroethics of Biomarkers should be of interest to those within neuroethics, medical ethics, and the philosophy of psychiatry.

This volume presents a number of controversial cases of enforced medical treatment from around the globe, providing for the first time a common, biopolitcal framework for all of them. Bringing together all these real cases guarantees that a new, more complete understanding of the topic will be within grasp for readers unacquainted with the aspects involved in these cases. On the one hand, readers interested mainly in the legal and medical dimensions of cases like those considered will benefit from the explanation of the biopolitical framework within which each case develops. On the other hand, those focusing on only one of the situations presented here will find the parallels between the cases an interesting expansion of the complexity of the problem. Despite the book's ambitious goal, for those willing to use it as supplemental material or interested in only one of the cases, the chapters can function as self-standing pieces to be read separately. This volume will be a valuable tool for both academics and professionals. Bioethicists in both the analytic and continental traditions, will find the book interesting for not only the specific concepts and issues considered, but also for its constructive bridging of the two schools of thought. In addition to philosophers, the structure of this work will also appeal to lawyers, doctors, human rights activists, and anyone concerned in the most disparate way with real-life cases of enforced medical treatment.

This volume contributes to the growing literature on the morality of procreation and parenting. About half of the chapters take up questions about the morality of bringing children into existence. They discuss the following questions: Is it wrong to create human life? Is there a connection between the problem of evil and the morality of procreation? Could there be a duty to procreate? How do the environmental harms imposed by procreation affect its moral status? Given these costs, is the value of establishing genetic ties ever significant enough to render procreation morally permissible? And how should government respond to peoples' motives for procreating? The other half of the volume considers moral and political questions about adoption and parenting. One chapter considers whether the choice to become a parent can be rational. The two following chapters take up the regulation of adoption, focusing on whether the special burdens placed on adoptive parents, as compared to biological parents, can be morally justified. The book concludes by considering how we should conceive of adequacy standards in parenting and what resources we owe to children. This collection builds on existing literature by advancing new arguments and novel perspectives on existing debates. It also raises new issues deserving of our attention. As a whole it is sure to generate further philosophical debate on pressing and rich questions surrounding the bearing and rearing of children.

'Clinical epidemiology' is now widely promoted and taught as a 'basic science' of Evidence-Based Medicine, of clinical EBM to be specific. This book, however, is mostly about that which Miettinen takes to be the necessary substitute for this now-so-fashionable subject - namely, Theory of Clinical Medicine together with its subordinate Theory of Clinical Research. The leit motif in all of this is Miettinen's perception of the need, and opportunity, to bring major improvements into clinical medicine in this Information Age, now that theoretical progress has made feasible the development of practice-guiding Expert Systems for it. Parts of this text constitute essential reading for whoever is expected, or otherwise inclined, to study - or teach - 'clinical epidemiology,' and the same is true of those who set policy for the education of future clinicians; but practically all of it is essential reading for future - and current - academics in the various disciplines of clinical medicine. After all, the text is the result of a concentrated effort, over a half-century no less, to really understand both clinical and community medicine and the research to advance the knowledge-base of these. Research epidemiologists, too, will find this text interesting and instructive.

Many deep concerns in the life sciences and medicine have to do with the enactment, ordering and displacement of a broad range of values. This volume articulates a pragmatist stance for the study of the making of values in society, exploring various sites within life sciences and medicine and asking how values are at play. This means taking seriously the work scientists, regulators, analysts, professionals and publics regularly do, in order to define what counts as proper conduct in science and health care, what is economically valuable, and what is known and worth knowing. A number of analytical and methodological means to investigate these concerns are presented. The editors introduce a way to indicate an empirically oriented research program into the enacting, ordering and displacing of values. They argue that a research programme of this kind, makes it possible to move orthogonally to the question of what values are, and thus ask how they are constituted. This rectifies some central problems that arise with approaches that depend on stabilized understandings of value. At the heart of it, such a research programme encourages the examination of how and with what means certain things come to count as valuable and desirable, how registers of value are ordered as well as displaced. It further encourages a sense that these matters could be, and sometimes simultaneously are, otherwise.

While procreation is ubiquitous, attention to the ethical issues involved in creating children is relatively rare. In Debating Procreation, David Benatar and David Wasserman take opposing views on this important question. David Benatar argues for the anti-natalist view that it is always wrong to bring new people into existence. He argues that coming into existence is always a serious harm and that even if it were not always so, the risk of serious harm is sufficiently great to make procreation wrong. In addition to these "philanthropic" arguments, he advances the "misanthropic" one that because humans are so defective and cause vast amounts of harm, it is wrong to create more of them. David Wasserman defends procreation against the anti-natalist challenge. He outlines a variety of moderate pro-natalist positions, which all see procreation as often permissible but never required. After criticizing the main anti-natalist arguments, he reviews those pronatalist positions. He argues that constraints on procreation are best understood in terms of the role morality of prospective parents, considers different views of that role morality, and argues for one that imposes only limited constraints based on the well-being of the future child. He then argues that the expected good of a future child and of the parent-child relationship can provide a strong justification for procreation in the face of expected adversities without giving individuals any moral reason to procreate

This textbook presents epidemiology in a practical manner, contextualized with discussions of theory and ethics, so that students and professionals from all academic backgrounds may develop a deep appreciation for how to conduct and interpret epidemiological research. Readers will develop skills to: -Search for and appraise literature critically, -Develop important research questions, -Design and implement studies to address those questions, -Perform and interpret fundamental statistical estimations and tests, -Consider the ethical implications of all stages of research, -Report findings in publications, and -Advocate for change in the public health setting. Epidemiology is and will remain a discipline in motion, and this textbook aims at reflecting this dynamism and keeping pace with its momentum. This textbook is not only a classroom tool with high utility but also an essential reference and guide for those engaging in research involving human subjects.

The book provides an in-depth discussion on the human nature concept from different perspectives and from different disciplines, analyzing its use in the doping debate and researching its normative overtones. The relation between natural talent and enhanced abilities is scrutinized within a proper conceptual and theoretical framework: is doping to be seen as a factor of the athlete's dehumanization or is it a tool to fulfill his/her aspirations to go faster, higher and stronger? Which characteristics make sports such a peculiar subject of ethical discussion and what are the, both intrinsic and extrinsic, moral dangers and opportunities involved in athletic enhancement? This volume combines fundamental philosophical anthropological reflection with applied ethics and socio-cultural and empirical approaches. Furthermore guidelines will be presented to decision- and policy-makers on local, national and international levels. Zooming in on the intrinsic issue of what is valuable about our homo sapiens biological condition, this volume devotes only scant attention to the specific issue of natural talent and why such talent is appreciated so differently than biotechnological origins of ability. In addition, specific aspects of sports such as its competitive nature and its direct display of bodily prowess provide good reason to single out the issue of natural athletic talent for sustained ethical scrutiny.