An authoritative introduction to bioethics, "Life Choices "examines a comprehensive range of ethical questions and brings together some of the most probing and instructive essays published in the field.

Some of the articles are classics in the literature of bioethics, while others address current issues. Topics include moral decision making, abortion, euthanasia and assisted suicide, life-sustaining technologies, organ transplantation, reproductive technologies, and the allocation of health care resources.

This second edition features new sections on the goals and allocation of medicine and on the cloning of human beings. It also includes new articles on genetics, the duty to die, and ethical theory.

Written by the foremost authorities in bioethics, "Life Choices" provides a comprehensive introduction to the field. Instructors who have used the first edition as a text will welcome this new, updated edition. Scholars and health care practitioners will find it useful as a valuable reference on a wide range of bioethical issues.

In this comprehensive updated introduction to animal ethics, Lori Gruen weaves together poignant and provocative case studies with discussions of ethical theory, urging readers to engage critically and reflect empathetically on our relationships with other animals. In clear and accessible language, Gruen discusses a range of issues central to human-animal relations and offers a reasoned new perspective on key debates in the field. She analyses and explains a range of theoretical positions and poses challenging questions that directly encourage readers to hone their ethical reasoning skills and to develop a defensible position about their own practices. Her book will be an invaluable resource for students in a wide range of disciplines including ethics, environmental studies, veterinary science, gender studies, and the emerging field of animal studies. The book is an engaging account of animal ethics for readers with no prior background in philosophy.

In Nature Ethics: An Ecofeminist Perspective, Marti Kheel explores the underlying worldview of "nature ethics," offering an alternative ecofeminist perspective. She focuses on four prominent representatives of holist philosophy: two early conservationists (Theodore Roosevelt and Aldo Leopold) and two contemporary philosophers (Holmes Rolston III, and transpersonal ecologist Warwick Fox). Kheel argues that in directing their moral allegiance to abstract constructs (e.g. species, the ecosystem, or the transpersonal Self) these influential nature theorists represent a masculinist orientation that devalues concern for individual animals. Seeking to heal the divisions among the seemingly disparate movements and philosophies of feminism, animal advocacy, environmental ethics, and holistic health, Kheel proposes an ecofeminist philosophy that underscores the importance of empathy and care for individual beings as well as larger wholes.

Solving intractable biotechnological questions of evolution, medicine, and genetics is now easier due to methods permitting the rapid analysis of molecular sequence data. These advances have exposed ethical and policy concerns. How would genomic information be used and by whom? Should individuals be able to make decisions regarding their own genomic data? How accurate are these genetic tests and how should they be regulated? These and other ethical conundrums are the subject of this book. Bioethicists, biomedical policy experts and lawyers, physicians, nursing and allied health students as well as science educators will find this book helpful and engaging in exploring the complexities of modern evolutionary, genetic and biomedical data.

In recent years concerns over the use of results of scientific advances, expectations about how medical decisions are made, and demographic changes have raised ethical questions about how resources are allocated, and how the principles of beneficence, and respect for patient autonomy are applied. The effect that bioethics can have on policy decisions and health care delivery demand an enhanced approach to our understanding of such complex issues. This volume opens a window to how empirical social research can be used to illuminate and answer such quandaries and offers a practical resource for those wishing to engage in this type of research. Through a thorough look at both quantitative and qualitative methods utilized in key research investigations in bioethics, the book examines the impact of such investigations on clinical and policy decision-making, scholarship and on the advancement of theory. The varied sociological and anthropological research examples that are presented allow readers to better understand the richness and breadth of such work as well as relevant practical and theoretical approaches.
Last, but not least, our aim with this book is to stimulate further discussion of avenues toward a more solid integration of bioethics and empirical social research and, in that process, further our understanding of the complex bioethical environment surrounding us.
PracticalOffers insights into clinical and policy implications of empirical research
In-depthEnhances understanding of methodologies as applied to bioethics
Comprehensive--Gives a range of examples of empirical bioethics studies
InterdisciplinaryGeared to a wide audience
Reference sourceincludes a largenumber of references

Solving intractable biotechnological questions of evolution, medicine, and genetics is now easier due to methods permitting the rapid analysis of molecular sequence data. These advances have exposed ethical and policy concerns. How would genomic information be used and by whom? Should individuals be able to make decisions regarding their own genomic data? How accurate are these genetic tests and how should they be regulated? These and other ethical conundrums are the subject of this book. Bioethicists, biomedical policy experts and lawyers, physicians, nursing and allied health students as well as science educators will find this book helpful and engaging in exploring the complexities of modern evolutionary, genetic and biomedical data.

A tightly argued and expansive examination of the pitfalls of transhumanism that reacquaints us with what it means to live well. Advocates of transhumanism, or "radical" enhancement, urge us to pursue the biotechnological heightening of select capacities - above all, cognitive ability - so far beyond any human limit that the beings with those capacities would exist on a higher ontological plane. For proponents of such views, humanity's self-transcendence through advancements in science and technology may even be morally required. Consequently, the human stakes of how we respond to transhumanism are immeasurably high. In Posthuman Bliss? The Failed Promise of Transhumanism, Susan B. Levin challenges transhumanists' overarching commitments regarding the mind and brain, ethics, liberal democracy, knowledge, and reality, showing their notion of humanity's self-transcendence into "posthumanity" to be little more than fantasy. Uniting philosophical with scientific arguments, Levin mounts a significant challenge to transhumanists' claim that science and technology support their vision of posthumanity. In a clear and engaging style, she dismantles transhumanists' breezy assurances that posthumans will emerge if we but allocate sufficient resources to that end. Far from offering theoretical and practical "proof of concept" for the vision that they urge upon us, Levin argues, transhumanists engage inadequately with cognitive psychology, biology, and neuroscience, often relying on questionable or outdated views within those fields. Having shown in depth why transhumanism should be rejected, Levin argues forcefully for a holistic perspective on living well that is rooted in Aristotle's virtue ethics but that is adapted to liberal democracy. This holism is thoroughly human, in the best of senses: It directs us to consider worthy ends for us as human beings and to do the irreplaceable work of understanding ourselves rather than relying on technology and science to be our salvation.

This is an open access title available under the terms of a CC BY-NC-ND 4.0 International licence. It is free to read at Oxford Scholarship Online and offered as a free PDF download from OUP and selected open access locations. Personal autonomy is often lauded as a key value in contemporary Western bioethics. Though the claim that there is an important relationship between autonomy and rationality is often treated as uncontroversial in this sphere, there is also considerable disagreement about how we should cash out the relationship. In particular, it is unclear whether a rationalist view of autonomy can be compatible with legal judgments that enshrine a patient's right to refuse medical treatment, regardless of whether the reasons underpinning the choice are known and rational, or indeed whether they even exist. Jonathan Pugh brings recent philosophical work on the nature of rationality to bear on the question of how we should understand personal autonomy in contemporary bioethics. In doing so, he develops a new framework for thinking about the concept of autonomy, one that is grounded in an understanding of the different roles that rational beliefs and rational desires have to play in it. Pugh's account allows for a deeper understanding of d the relationship between our freedom to act and our capacity to decide autonomously. His rationalist perspective is contrasted with other prominent accounts of autonomy in bioethics, and the revisionary implications it has for practical questions in biomedicine are also outlined.

Metastatic cancer and costly precision medicines generate extremely complex problems of health care justice. Targeted cancer therapies yield only very marginal gains in life expectancy for most patients at very great cost, thereby threatening the just allocation of limited health care resources. Philosophers have high hopes for the utility of their theories of justice in addressing the challenges of resource allocation; however, none of these theories can address adequately the "wicked" ethical problems that have resulted from these targeted therapies. What we need instead, bioethicist Leonard M. Fleck argues, is a political conception of health care justice, following Rawls, and a fair and inclusive process of rational democratic deliberation governed by public reason. His account makes the basic assumption that we have only limited health care resources to meet unlimited health care needs generated by emerging medical technologies. The primary ethical and political virtue of rational democratic deliberation is that it allows citizens to fashion autonomously shared understandings of how to fairly address the complex problems of health care justice generated by precision medicine. While ideally just outcomes are a moral and political impossibility, "wicked" problems can metastasize if rationing decisions are made invisibly-in ways effectively hidden from those affected by those decisions. As Fleck demonstrates, a fair and inclusive process of democratic deliberation could make these "wicked" problems visible, and subject, to public reason.

Elizabeth Anscombe is now recognised as one of the most important philosophers of the second half of the 20th century. She left a large corpus of work, wide-ranging in content, always original and bold. Her monograph Intention, published in 1957, is a modern classic, and was described by Donald Davidson as "the most important treatment of action since Aristotle." Her writings in ethics have inspired countless discussions, and she has been credited with having changed the face of Anglophone moral philosophy by reviving and arguing for virtue ethics, now a major field. Since Anscombe's death in 2001, her philosophical work has received a steadily increasing level of attention worldwide. Anscombe is often difficult to read, and she has certainly been frequently misunderstood, but the sympathetic interest in her work which is now evident in so many quarters is making it possible for a true picture to begin to emerge of the range, depth, and power of her contribution to philosophy. The Oxford Handbook of Elizabeth Anscombe conveys something of that emerging picture of Anscombe's overall philosophy-showing the great fecundity of her ideas in essays that develop and expand on those ideas-and allows contributors to engage critically with Anscombe, not merely to expound what she said. The handbook opens with an introduction that addresses the question of the unity in diversity of Anscombe's philosophy, relating this to the twenty-two essays that follow. The handbook is divided into parts along broadly thematic lines, addressing: intention, ethical theory, human life, the first person, and Anscombe on other philosophers.

In his 2006 State of the Union speech, President George W. Bush asked the U.S. Congress to prohibit the "most egregious abuses of medical research," such as the "creation of animal--human hybrids." The president's message echoed that of a 2004 report by the President's Council on Bioethics, which recommended that hybrid human--animal embryos be banned by Congress.

Discussions of early interspecies research, in which cells or DNA are interchanged between humans and nonhumans at early stages of development, can often devolve into sweeping statements, colorful imagery, and confusing policy. Although today's policy advisory groups are becoming more informed, debate is still limited by the interchangeable use of terms such as chimeras and hybrids, a tendency to treat all forms of interspecies alike, the failure to distinguish between laboratory research and procreation, and not enough serious policy justification. Andrea Bonnicksen seeks to understand reasons behind support of and disdain for interspecies research in such areas as chimerism, hybridization, interspecies nuclear transfer, cross-species embryo transfer, and transgenics. She highlights two claims critics make against early interspecies studies: that the research will violate human dignity and that it can lead to procreation. Are these claims sufficient to justify restrictive policy?

Bonnicksen carefully illustrates the challenges of making policy for sensitive and often sensationalized research -- research that touches deep-seated values and that probes the boundary between human and nonhuman animals.

Human Embryos and Preimplantation Genetic Technologies: Ethical, Social, and Public Policy Aspects presents the first holistic analysis of PGD and PGS as it is practiced and regulated worldwide. In addition to scientific and technical aspects, the book provides perspectives on the ethical, legal, religious, policy and social implications of global assisted reproduction technologies, including in Africa, Asia, Europe, North and South America, and Australia. Chapters cover history, ethics, feminism, family dynamics, psychological and interpersonal factors, the current state of PGD and PGS in 20 different sovereign nations and religious communities, and provide an analysis of public policy concerns and future directions.

Prenatal diagnosis, especially noninvasive prenatal testing (NIPT), has changed the experience of pregnancy, prenatal care and responsibilities in Israel and Germany in different ways. These differences reflect the countries' historical legacies, medico-legal policies, normative and cultural identities. Building on this observation, the contributors of this book present conversations between leading scholars from Israel and Germany based on an empirical bioethical perspective, analyses about the reshaping of 'life' by biomedicine, and philosophical reflections on socio-cultural claims and epistemic horizons of responsibilities. Practices and discussions of reproductive medicine transform the concepts of responsibility and irresponsibility.

Research on human beings saves countless lives, but has at times harmed the participants. To what degree then should government regulate science, and how? The horrors of Nazi concentration camp experiments and the egregious Tuskegee syphilis study led the US government, in 1974, to establish Research Ethics Committees, known as Institutional Review Boards (IRBs) to oversee research on humans. The US now has over 4,000 IRBs, which examine yearly tens of billions of dollars of research - all studies on people involving diseases, from cancer to autism, and behavior. Yet ethical violations persist. At the same time, critics have increasingly attacked these committees for delaying or blocking important studies. Partly, science is changing, and the current system has not kept up. Since the regulations were first conceived 40 years ago, research has burgeoned 30-fold. Studies often now include not a single university, but multiple institutions, and 40 separate IRBs thus need to approve a single project. One committee might approve a study quickly, while others require major changes, altering the scientific design, and making the comparison of data between sites difficult. Crucial dilemmas thus emerge of whether the current system should be changed, and if so, how. Yet we must first understand the status quo to know how to improve it. Unfortunately, these committees operate behind closed doors, and have received relatively little in-depth investigation. Robert Klitzman thus interviewed 45 IRB leaders and members about how they make decisions. What he heard consistently surprised him. This book reveals what Klitzman learned, providing rare glimpses into the conflicts and complexities these individuals face, defining science, assessing possible future risks and benefits of studies, and deciding how much to trust researchers - illuminating, more broadly, how we view and interpret ethics in our lives today, and perceive and use power. These committees reflect many of the most vital tensions of our time - concerning science and human values, individual freedom, government control, and industry greed. Ultimately, as patients, scientists, or subjects, the decisions of these men and women affect us all.

People have always sought medical care that is tailored to every individual patient. Alongside with the historical development of institutions of care, the vision of personal and 'holistic' care persisted. Patient-centred medicine, interpersonal communication and shared decision making have become central to medical practice and services. This evolving vision of 'personalized medicine' is in the forefront of medicine, creating debates among ethicists, philosophers and sociologists of medicine about the nature of disease and the definition of wellness, the impact on the daily life of patients, as well as its implications on low-income countries. Is increased 'precision' also an improvement on the personal aspects of care or erosion of privacy? Do 'precise' and 'personalized' approach marginalize public health, and can this care be personalized without attention to culture, economy and society? The book provides a multidisciplinary and interdisciplinary discussion of the ethos and ethics of precision/personal medicine, involving scientists who have shaped the field, in dialogue with ethicists, social scientists and philosophers of science. The contributing scholars come from all over the world and from different cultural backgrounds providing reflective perspectives of history of ideas, critical theory and technology assessment, together with the actual work done by pioneers in the field. It explores issues such as global justice, gender, public health, pharmaceutical industry, international law and religion, and explores themes discussed in relation to personalized medicine such as new-born screening and disorders of consciousness. This book will be of interest to academicians in bioethics, history of medicine, social sciences of medicine as well as general educated readers.

An accessible synthesis of ethical issues raised by artificial intelligence that moves beyond hype and nightmare scenarios to address concrete questions. Artificial intelligence powers Google's search engine, enables Facebook to target advertising, and allows Alexa and Siri to do their jobs. AI is also behind self-driving cars, predictive policing, and autonomous weapons that can kill without human intervention. These and other AI applications raise complex ethical issues that are the subject of ongoing debate. This volume in the MIT Press Essential Knowledge series offers an accessible synthesis of these issues. Written by a philosopher of technology, AI Ethics goes beyond the usual hype and nightmare scenarios to address concrete questions. Mark Coeckelbergh describes influential AI narratives, ranging from Frankenstein's monster to transhumanism and the technological singularity. He surveys relevant philosophical discussions: questions about the fundamental differences between humans and machines and debates over the moral status of AI. He explains the technology of AI, describing different approaches and focusing on machine learning and data science. He offers an overview of important ethical issues, including privacy concerns, responsibility and the delegation of decision making, transparency, and bias as it arises at all stages of data science processes. He also considers the future of work in an AI economy. Finally, he analyzes a range of policy proposals and discusses challenges for policymakers. He argues for ethical practices that embed values in design, translate democratic values into practices and include a vision of the good life and the good society.

The foundations of research ethics are riven with fault lines emanating from a fear that if research is too closely connected to weighty social purposes an imperative to advance the common good through research will justify abrogating the rights and welfare of study participants. The result is an impoverished conception of the nature of research, an incomplete focus on actors who bear important moral responsibilities, and a system of ethics and oversight highly attuned to the dangers of research but largely silent about threats of ineffective, inefficient, and inequitable medical practices and health systems. In For the Common Good: Philosophical Foundations of Research Ethics, Alex John London defends a conception of the common good that grounds a moral imperative with two requirements. The first is to promote research that generates the information necessary to enable key social institutions to effectively, efficiently, and equitably safeguard the basic interests of individuals. The second is to ensure that research is organized as a voluntary scheme of social cooperation that respects its various contributors' moral claims to be treated as free and equal. Connecting research to the goals of a just social order grounds a framework for assessing and managing research risk that reconciles these requirements and justifies key oversight practices in non-paternalistic terms. Reconceiving research ethics as resolving coordination problems and providing credible assurance that these requirements are being met expands the issues and actors that fall within the purview of the field and provides the foundation for a more unified and coherent approach to domestic and international research. This is an open access title available under the terms of a CC BY-NC-ND 4.0 license. It is free to read at Oxford Scholarship Online and offered as a free PDF download from OUP and selected open access locations.

Bioethics asks fundamental questions. "Who lives? Who dies? Who decides?" These questions are relevant to us all. Too often, the general public's sole encounter with these weighty questions is through sound bites fed to us by the media-where complex, difficult matters are typically presented in superficial and inaccurate terms. Here, renowned bioethicist Albert R. Jonsen equips readers with the tools and background to navigate the fascinating and complex landscape of bioethics. Bioethics Beyond the Headlines is a primer. You will not find convoluted philosophical arguments in this volume. Rather, you will find an engaging sampling of the key questions in bioethics, including euthanasia, assisted reproduction, cloning and stem cells, neuroscience, access to healthcare, and even research on animals and questions of environmental ethics-areas typically overlooked in general introductions to bioethics. But a "primer" is not merely a first book-it should also "prime" the interest of the reader, to prepare the mind for a more expansive venture into these issues. Bioethics Beyond the Headlines intends to do just that.

How does death help us understand the living? Death is more than the last event of life; it is interwoven into our growth, development, protection against disease, and more. It influences the direction of entire species via the cycle of a lifespan, and it involves asking many fascinating questions. How do we differentiate between life and death, though? How do we know when a person, animal, or cell is really dead? How much grey area is there in the science? Why do we age? Can we do anything about it? Scientifically, there's much we can learn about a living thing from its cells. In all living things, cells seem to carry "death" gene programs. Some living organisms have created systems to use these to their own advantage. Humans, for example, use the death of specific cells to hone our immune system and to give us fingernails and hair. Perhaps the most dramatic use occurs during the metamorphosis of insects and frogs. Even single-celled organisms use "quorum sensing" to eliminate some cells to ensure the overall survival of their colony in harsh environments. Thus, there is more to death than just dying. This latest book from science writer Gary C. Howard ties together the many ways that death helps us understand life. He synthesizes the involvement and relation of cells, tissues, organisms, and populations, explaining what happens at the end of life. Between discussions about popular topics such as the ethics of extending life and cell regeneration, Howard also answers fascinating questions about life and death. The resulting book examines how the end of life is determined and what we can learn from this process.

The Universal Declaration on Bioethics and Human Rights, 2005, marked a significant step towards the recognition of universal standards in the field of science and medicine. This book provides an overview of the ethical and legal developments which have occurred in the field of bioethics and human rights since then. The work critically analyzes the Declaration from an ethical and legal perspective, commenting on its implementation, and discussing the role of non-binding norms in international bioethics. The authors examine whether the Declaration has contributed to the understanding of universal or global bioethics, and to what degree states have implemented the principles in their domestic legislation. The volume explores the currency of the Declaration vis-a-vis the more recent developments in technology and medicine and looks ahead to envisage the major bioethical challenges of the next twenty years. In this context, the book offers a comprehensive ethical and legal study of the Declaration with an in-depth analysis of the meaning of the provisions, in order to clarify the extension of human rights in the field of medicine and the obligations incumbent upon UNESCO member States, with reference to their implementation practice.

In recent decades there has been an explosion in work in the social and physical sciences describing the similarities between human and nonhuman as well as human and non-animal thinking. This work has explicitly decentered the brain as the sole, self-contained space of thought, and it has found thinking to be an activity that operates not only across bodies but also across bodily or cellular membranes, as well as multifaceted organic and inorganic environments. For example, researchers have looked at the replication and spread of slime molds (playfully asking what would happen if they colonized the earth) to suggest that they exhibit 'smart behavior' in the way they move as a potential way of considering the spread of disease across the globe. Other scholars have applied this model of non-human thought to the reach of data mining and global surveillance. In The Biopolitics of Alphabets and Embryos, Ruth Miller argues that these types of phenomena are also useful models for thinking about the growth, reproduction, and spread of political thought and democratic processes. Giving slime, data and unbounded entities their political dues, Miller stresses their thinking power and political significance and thus challenges the anthropocentrism of mainstream democratic theories. Miller emphasizes the non-human as highly organized, systemic and productive of democratic growth and replication. She examines developments such as global surveillance, embryonic stem cell research, and cloning, which have been characterized as threats to the privacy, dignity, and integrity of the rational, maximizing and freedom-loving democratic citizen. By shifting her level of analysis from the politics of self-determining subjects to the realm of material environments and information systems, Miller asks what might happen if these alternative, nonhuman thought processes become the normative thought processes of democratic engagement.

Emerging medical technologies are changing our views on human nature and what it means to be alive, healthy, and leading a good life. Reproductive technologies, genetic diagnosis, organ transplantation, and psychopharmacological drugs all raise existential questions that need to be tackled by way of philosophical analysis. Yet questions regarding the meaning of life have been strangely absent from medical ethics so far. This book brings phenomenology, the main player in the continental tradition of philosophy, to bioethics, and it does so in a comprehensive and clear manner. Starting out by analysing illness as an embodied, contextualized, and narrated experience, the book addresses the role of empathy, dialogue, and interpretation in the encounter between health-care professional and patient. Medical science and emerging technologies are then brought to scrutiny as endeavours that bring enormous possibilities in relieving human suffering but also great risks in transforming our fundamental life views. How are we to understand and deal with attempts to change the predicaments of coming to life and the possibilities of becoming better than well or even, eventually, surviving death? This is the first book to bring the phenomenological tradition, including philosophers such as Martin Heidegger, Edith Stein, Maurice Merleau-Ponty, Jean-Paul Sartre, Hans-Georg Gadamer, Paul Ricoeur, Hans Jonas, and Charles Taylor, to answer such burning questions.

This volume explores the ethics of making or expanding families through adoption or technologically assisted reproduction. For many people, these methods are separate and distinct: they can choose either adoption or assisted reproduction. But for others, these options blend together. For example, in some jurisdictions, the path of assisted reproduction for same-sex couples is complicated by the need for the partner who is not genetically related to the resulting child to adopt this child if she wants to become the child's legal parent. The essays in this volume critically examine moral choices to pursue adoption, assisted reproduction, or both, and highlight the social norms that can distort decision-making. Among these norms are those that favour people having biologically related children ('bionormativity') or that privilege a traditional understanding of family as a heterosexual unit with one or more children where both parents are the genetic, biological, legal, and social parents of these children. As a whole, the book looks at how adoption and assisted reproduction are morally distinct from one another, but also emphasizes how the two are morally similar. Choosing one, the other, or both of these approaches to family-making can be complex in some respects, but ought to be simple in others, provided that one's main goal is to become a parent.

Transplantation is a medically successful and cost-effective way to treat people whose organs have failed-but not enough organs are available to meet demand. Ethics and the Acquisition of Organs is concerned with the major ethical problems raised by policies for acquiring organs. The main topics are the rights of the dead, the role of the family, opt in and opt out systems, the conscription of organs, living organ donation from adults and children, directed donation and priority for donors, and the sale of organs. In this ground-breaking work, T. M. Wilkinson uses concepts from moral and political theory such as autonomy, rights, posthumous interests, justice, and well-being, in a context informed by the clinical, legal, and policy aspects of transplantation. The result is a rigorous philosophical exploration of real problems and options. He argues that the ethics of acquiring organs for transplantation is not only of great intellectual interest, but also of practical importance. As such, this book will be of profit not only to students and academics who work in applied ethics and bioethics, but also to the lawyers, policy-makers, clinicians, and lobby groups interested in transplantation.