High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective.
HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge.
* Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory
* Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities)
* Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase

Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science where precise structural determination is required and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy.
* Provides updates on the latest developments in NMR spectroscopy
* Includes comprehensive review articles
* Highlights the increasing importance of NMR spectroscopy as a technique for structural determination

This annual review of the literature presents a comprehensive and critical survey of the vast field of study involving organophosphorus compounds, from phosphines and related P-C bonded compounds to phosphorus acids, phosphine chalcogenides and nucleotides. The Editors have added to the content with a timely chapter on the recent developments in green synthetic approaches in organophosphorus chemistry to reflect current interests in the area. With an emphasis on interdisciplinary content, this book is aimed at the worldwide organic chemistry and engineering research communities.

From cooking to medicine, from engineering to art, chemistry-the science of molecules-is everywhere. A celebration of the molecules of chemistry, Every Molecule Tells a Story celebrates the molecules responsible for the experiences of everyday life: the air we breathe; the water we drink; the chemicals that fuel our living; the steroids that give us sex; the colours of the seasons; the drugs that heal us; and the scented molecules that enrich our diet and our encounters with each other. You can't see them, but you know that they are there. Unveiling the structures of poisonous "natural" substances and beneficial man-made molecules, this book brushes away any preconceived notions about chemistry to demonstrate why and how molecules matter.

A HANDS-ON MANUAL FOR THE SAFETY AND DESIGN OF COMPLEX PROCESS VENTING SYSTEMS

Process vent header collection systems are subject to continually varying compositions and flow rates and thus present significant challenges for safe design. Due to increasingly demanding safety, health, environmental, and property protection requirements, today's industrial designers are faced with the need

to create increasingly complex systems for more effective treatment, dispersal, or disposal of process gases.

Safe Design and Operation of Process Vents and Emission Control Systems provides cutting-edgeguidance for the design, evaluation, and operation of these systems, with emphasis on: Preventing fires, explosions, and toxic releases Maintaining safe vent conditions Understanding normal process operations, such as intentional routine controlled venting and emergency operations, like overpressure relief Mitigating the impacts of end-of-line treatment devices, such as scrubbers, flares, and thermal oxidizers, on the vent header system Complying with regulations

Written by a team of process safety experts from the chemical, pharmaceutical, and petroleum industries, the book includes a wealth of real-world examples and a thorough overview of the tools and methods used in the profession.

Dislocations are lines of irregularity in the structure of a solid analogous to the bumps in a badly laid carpet. Like these bumps they can be easily moved, and they provide the most important mechanism by which the solid can be deformed. They also have a strong influence on crystal growth and on the electronic properties of semiconductors.
.Influence of dislocations on piezoelectric behavior
.New mechanisms for hardening in twinned crystals
.Bringing theories of martensite transformation into agreement
.Atomic scale motion of dislocations in electron microscopy
.Dislocation patterns deduced from X-ray diffraction
.Role of dislocations in friction
.Dislocation motion in quasicrystals

Recent Progress in Mesostructured Materials is a selection of oral and poster communications presented during the 5th International Mesostructured Materials Symposium (5th IMMS2006). Authorized by International Mesostructured Material Association (IMMA) and hosted by the Fudan University, China. The scope of this involved field covers both traditional inorganic mesostructured molecular sieves and mesostructured materials like organic polymers, metals, organic-inorganic nanocomposites, and ordered mesoporous carbons, the hot topics in chemistry, crystallization, structure, liquid crystalline, catalysis and materials science. This symposium provided a forum for the presentation of the most novel development and knowledge in the science and technology of mesostructured materials. Papers presented cover a wide range of topics that include synthesis, structure determination, characterisation, modelling, and application in catalysis, adsorption, biochemistry and advanced material sciences.
* This highly visual book is a must for readers looking to stay up-to-date on mesostructure science
* A selection of more than 200 oral and poster papers, covering research aspects/developing trends of mesostructured materials
* An important reference for those working in the material science, catalysis and biotechnology fields

Advanced Chemistry of Monolayers at Interfaces describes the advanced chemistry of monolayers at interfaces. Focusing on the recent trends of methodology and technology, which are indispensable in monolayer science. They are applied to monolayers of surfactants, amphiphiles, polymers, dendrimers, enzymes, and proteins, which serve many uses.
Introduces the methodologies of scanning probe microscopy, surface force instrumentation, surface spectroscopy, surface plasmon optics, reflectometry, and near-field scanning optical microscopy. Modern interface reaction method, lithographic technology and different types of monolayers like adsorption, Langmuir and Langmuir-Blodgett monolayers at air/liquid, liquid/liquid, liquid/solid and air/solid interfaces, are all covered.
* Introducing novel methodologies and technologies
* Covering the different types of monolayers
* Discusses all currently available instrumental techniques for studying all types of monolayer

This third volume in the series represents the Proceedings of the 3rd International Nanophotonics Symposium, July 6-8, 2006, Icho-Kaikan, Osaka University, Osaka, Japan. Over a two-day symposium, distinguished scientists from around the world convened to discuss the latest progress in this field and the conclusions have been summarised in Nano Biophotonics: Science and Technology. The contents of this book have been compiled by invited lecturers, research members of the relevant projects/program, and some of general participants. The book has 27 chapters which are classified into 4 parts; nano bio-spectroscopy, nano bio-dynamics, nano bio-processing, and nano bio-devices.
* Bridges the gap between conventional photophysics & photochemistry and nanoscience
* Continuing the series that focuses on 'hot' areas of photochemistry, optics, material science and bioscience

Metal-Sulfur clusters play an essential role in living organisms through the unique character of sulfur-metal bonding. The new volume in prestigious Metal Ions in Life Sciences explores different transition metal complexes with sulfur, their biosynthesis and biological functions in regulation of gene expression, catalysis of important metabolic reactions and protein structure arrangement.

Surfactants have been used for many industrial processes such as flotation, enhanced oil recovery, soil remediation and cleansing. Flotation technology itself has been used in industry since the end of the 19th century, and even today it is an important method for mineral processing and its application range is expanding to other areas. This technology has been used in the treatment of wastewater, industrial waste materials, separation and recycling of municipal waste, and some unit processes of chemical engineering. The efficiency of all these operations depends primarily on the interactions among surfactants, solids and media.
In this book, the fundamentals of solution chemistry of mineral/surfactant systems are discussed, as well as the important calculations involved. The influence of relevant physico-chemical conditions are also presented in detail.
* Introduces the fundamentals of solution chemistry of mineral/surfactant systems and important calculations involved
* Discusses the influence of relevant physico-chemical conditions
* Presents the relationship between the molecular structure of the flotation regents of solution chemistry and its characteristics

Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design. Section VII looks at Trends and Perspectives in the pharmaceuticals market.
* Critical reviews of the previous year's literature in many topics of interest to medicinal chemists
* Highlights major developments in medicinal chemistry
* Includes a comprehensive set of cumulative indices to easily locate topics in all published volumes

Nanostructured Materials for Solar Energy Conversion covers a wide variety of materials and device types from inorganic materials to organic materials. This book deals with basic semiconductor physics, modelling of nanostructured solar cell, nanostructure of conventional solar cells such as silicon, CIS and CdTe, dye-sensitized solar cell, organic solar cell, photosynthetic materials, fullerene, extremely thin absorber (ETA) solar cell, quantum structured solar cell, intermediate band solar cell, carbon nanotube, etc. including basic principle and the latest results. There are many books written on conventional p-n junction solar cells, but few books focus on new concepts in this area.
* Focuses on the use of nanostructured materials for solar energy
* Looks at a wide variety of materials and device types
* Covers both organic and inorganic materials

The declining supply of crude oils worldwide and the ever increasing demand for petroleum products from China, India, Europe and the US have recently propelled crude prices to unprecedented levels. The future availability of traditional crudes is becoming a source of discussion and debate.
Fischer-Tropsch Synthesis, Catalysts and Catalysis offers a timely and comprehensive report on the processing of relatively inexpensive coal deposits into transportation fluids using Fisher-Tropsch process Technology. In addition to recent catalysts and process developments, the book contains the history of the Fisher-Tropsch in Germany and Japan based on captured documents by allied forces.
* Increase the understanding of FT process development
* Addresses four major areas of interest in Fischer-Tropsch synthesis (FTS)

Advances in Physical Organic Chemistry provides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistry. The field is a rapidly developing one, with results and methodologies finding application from biology to solid state physics.
* Reviews the application of quantitative and mathematical methods towards understanding chemical problems
* Multidisciplinary volumes cover organic, organometallic, bioorganic, enzymes and materials topics

Inorganic Pollutants in Water provides a clear understanding of inorganic pollutants and the challenges they cause in aquatic environments. The book explores the point of source, how they enter water, the effects they have, and their eventual detection and removal. Through a series of case studies, the authors explore the success of the detection and removal techniques they have developed. Users will find this to be a single platform of information on inorganic pollutants that is ideal for researchers, engineers and technologists working in the fields of environmental science, environmental engineering and chemical engineering/ sustainability. Through this text, the authors introduce new researchers to the problem of inorganic contaminants in water, while also presenting the current state-of-the-art in terms of research and technologies to tackle this problem.