Energy and agriculture are both extremely broad subjects and their interactions - the subject of this book - cover almost the full spectrum of the agricultural sciences. Yet the subject is a relatively new one whose importance first received widespread recognition barely a decade ago, following the dramatic increase in oil prices during 1973. The impact of this increase was such as to promote a world-wide debate on the future direction that agriculture should take. This debate was, and is, of particular concern in countries where agriculture plays a leading role in economic and social development. During the last half century many national agricultural systems have been transformed from almost closed, self-sufficient systems with few locally produced inputs geared to satisfy local requirements, to intensive, open systems, utilizing large quantities of energy-rich inputs such as fossil fuel for manufactured agro-chemicals, water distribution and imported animal feedstuffs to produce a range of sophisticated products, often for export, which in tum require many energy-rich inputs for their marketing. This industrialization of agriculture has proved to be very successful in many respects and indeed was accepted as a general model for agricultural development allowing increased productivity and efficiency per unit land, labor and water, even in areas with limited natural resources.

A top priority in climate research is obtaining broad-extent and long-term data to support analyses of historical patterns and trends, and for model development and evaluation. Along with directly measured climate data from the present and recent past, it is important to obtain estimates of long past climate variations spanning multiple centuries and millennia. These longer time perspectives are needed for assessing the unusualness of recent climate changes, as well as for providing insight on the range, variation and overall dynamics of the climate system over time spans exceeding available records from instruments, such as rain gauges and thermometers. Tree rings have become increasingly valuable in providing this long-term information because extensive data networks have been developed in temperate and boreal zones of the Earth, and quantitative methods for analyzing these data have advanced. Tree rings are among the most useful paleoclimate information sources available because they provide a high degree of chronological accuracy, high replication, and extensive spatial coverage spanning recent centuries. With the expansion and extension of tree-ring data and analytical capacity new climatic insights from tree rings are being used in a variety of applications, including for interpretation of past changes in ecosystems and human societies. This volume presents an overview of the current state of dendroclimatology, its contributions over the last 30 years, and its future potential. The material included is useful not only to those who generate tree-ring records of past climate-dendroclimatologists, but also to users of their results-climatologists, hydrologists, ecologists and archeologists. 'With the pressing climatic questions of the 21st century demanding a deeper understanding of the climate system and our impact upon it, this thoughtful volume comes at critical moment. It will be of fundamental importance in not only guiding researchers, but in educating scientists and the interested lay person on the both incredible power and potential pitfalls of reconstructing climate using tree-ring analysis.', Glen M. MacDonald, UCLA Institute of the Environment, CA, USA 'This is an up-to-date treatment of all branches of tree-ring science, by the world's experts in the field, reminding us that tree rings are the most important source of proxy data on climate change. Should be read by all budding dendrochronology scientists.', Alan Robock, Rutgers University, NJ, USA

Changes in production, demand, supply, and trade patterns; the impact of green building and bioenergy on industry practices and policy infrastructure; and new economies with production advantages and large consumption bases all present challenges and opportunities in the forest sector. With contributions from leading experts in academia and professional organizations, The Global Forest Sector: Changes, Practices, and Prospects fills a gap in the literature that is preventing students, scholars, and policy makers from developing a timely, structured, big-picture view of forest sector business. In addition, the book reviews current thinking on a wide variety of business management issues in the forest sector.

The book covers managing change in the global forest sector and the impact of globalization on forest users. It discusses markets and market forces, new products and product categories, and the influence of China and Russia. The book then examines the environmental paradigm, including environmental activism, sustainability, and the impact of green building and bioenergy. The book concludes with coverage of the role of information technology, corporate social responsibility, innovation, and next steps.

Overall, this book helps readers both develop a bird s eye view of the changes surrounding the forest sector as well as have a magnified view of numerous managerial issues associated with these changes. The content paints a picture of the current and changing forest sector including the state of forests, the nature of markets, the newly emerged patterns of stakeholder impact, and evolution of key business practices. It provides the foundation needed to develop the conservation-based economy required for future success in the global forest sector."

Forests comprise the greatest storage of carbon on land, provide fuel for millions, are the habitat for most terrestrial biodiversity, and are critical to the economies of many countries. Yet changes in the extent and dynamics of forests are inherently difficult to detect and quantify. Remote sensing technologies may facilitate the measurement of some key forest properties which, when combined with other information contained in various computer models, may allow for the quantification of critical forest functions. This book explores how remote sensing and computer modeling can be combined to estimate changes in the carbon storage, or productivity, of forests - from the level of the leaf to the level of the globe. Land managers, researchers, policy makers and students will all find stimulating discussions among an international set of experts at the cutting edge of the interface between science, technology and management.

The subject of fruit ripening is one of vital interest and importance to the massive international fruit growing and fruit trade industries. This book is the definitive handbook on the subject, bringing together a vast wealth of important information from an experienced team of international contributors.

Comprising 26 chapters, this volume deals with the genetic transformation of medicinal plants. It describes methods to obtain plants resistant to insects, diseases, herbicides, and plants with an increased production of compounds of medicinal and pharmaceutical importance. The plant species included are "Ajuga reptans," "Anthemis nobilis," "Astragalus" spp., "Atropa" "belladonna," "Catharanthus roseus," "Datura" spp., "Duboisia" species, "Fagopyrum" spp., "Glycyrrhiza" "uralensis," "Lobelia" spp., "Papaver" "somniferum," "Panax" "ginseng," "Peganum" "harmala," "Perezia" spp., "Pimpinella" "anisum," "Phyllanthus" "niruri," "Salvia" "miltiorrhiza," "Scoparia dulcis," "Scutellaria" "baicalesis," "Serratula" "tinctoria," "Solanum aculeatissimum," "Solanum " "commersonii," "Swainsona galegifolia," tobacco, and "Vinca minor."
This book is of special interest to advanced students, teachers, and researchers in the field of pharmacy, plant tissue culture, phytochemistry, molecular biology, biomedical engineering, and plant biotechnology in general.

The 23rd annual meeting of the International Society on Oxygen Transport to Tissue took place from August 23-27, 1995, at the Station Square Sheraton along the shores of the Monongahela River where it meets with the Allegheny and Ohio Rivers to form the "Point" of the city of Pittsburgh. Pittsburgh was a convenient location for the meeting be ing between both the East and West coasts of the United States and between the Asian and European continents. It is easily accessible by air via its large international airport. In ad dition, Pittsburgh has just recently undergone a transition from the steel mills and indus tries of old to an age of computers and biotechnology as evidenced by the new Biotechnology Center of the University of Pittsburgh where a lunch and tour were pro vided for interested participants. On the tour, the participants got to see the mix of projects ranging from molecular biology to clinical projects studying membrane oxygenators, ven tricular assist devices, oxygen carriers, and more, representing the forefront of research on oxygen delivery systems to tissue.

Tropical climates, which occur between 23 Degrees30'N and S latitude (Jacob 1988), encompass a wide variety of plant communities (Hartshorn 1983, 1988), many of which are diverse in their woody floras. Within this geographic region, temperature and the amount and seasonality of rainfall define habitat types (UNESCO 1978). The F AO has estimated that there 1 are about 19 million km of potentially forested area in the global tropics, of which 58% were estimated to still be in closed forest in the mid-1970s (Sommers 1976; UNESCO 1978). Of this potentially forested region, 42% is categorized as dry forest lifezone, 33% is tropical moist forest, and 25% is wet or rain forest (Lugo 1988). The species diversity of these tropical habitats is very high. Raven (1976, in Mooney 1988) estimated that 65% of the 250,000 or more plant species of the earth are found in tropical regions. Of this floristic assemblage, a large fraction are woody species. In the well-collected tropical moist forest of Barro Colorado Island, Panama, 39. 7% (481 of 1212 species) of the native phanerogams are woody, arborescent species (Croat 1978). Another 21. 9% are woody vines and lianas. Southeast Asian Dipterocarp forests may contain 120-200 species of trees per hectare (Whitmore 1984), and recent surveys in upper Amazonia re corded from 89 to 283 woody species ~ 10 cm dbh per hectare (Gentry 1988). Tropical communities thus represent a global woody flora of significant scope.

The Dictionary contains the names of nearly 2500 plant species, in some cases including subspecies and varieties. Tropical crops from all parts of the world receive the same attention as those from the temperate zone. Common names are given not only in English, French, German, Portuguese and Spanish but also in many other languages, where such names are used in the technical literature. Agronomic plants' comprise not only the agricultural and horticultural crops but also pasture plants, green manure, soil covers, trees used in agroforestry, and major weeds. Also included are plants which are presently being discussed as new crops, with considerable economic value. The Dictionary will meet the needs not only of scientists in agriculture, botany and geography but also those of agricultural extensionists, merchants in agricultural products and professional translators.

For the last two decades the loss of, in particular, tropical rainforest has alarmed the public in the developed parts of the world. The debate has been characterised by a lack of understand ing of the causes and effects of the process, leading to the prevailing reaction being unquali fied condemnation. Such attitude has even been observed among scientists, claiming suprem acy to biodiversity conservation. Many scientific analyses are available, but the basis for so ber debates and appropriate actions is still highly insufficient. Two recent international initia tives! will hopefully lead to improved knowledge of deforestation and forest degradation as they recognise the need for studies to critically investigate those issues. This book will pro vide useful input to the initiatives. In my opinion, the scientific analyses have not sufficiently promoted the understanding that the fate of tropical forests is first and foremost a concern of the governments of the countries in which the forests are situated. Tropical forests may be important to the global environment and their rich biodiversity may be a human heritage. But their main importance is their poten tial contribution to improving livelihood in the countries in question.

Recent advances in our understanding of the fundamental role of bioactive lipids in normal and abnormal physiology was the theme of the XVlth International Spring Sympo- 6-9, 1996 at the George Washington University School sium on Health Sciences held on May of Medicine in Washington, D.C. Over 250 participants shared their latest findings on fundamental mechanisms in lipid metabolism, transport, and signal transduction. Most of the papers presented at the plenary sessions have been collected in this volume, which is divided into seven parts. The focus of Part I is on the new roles that fatty acids and esters play in cellular function. These activities include regulation of gene expression, control of eicosanoid-me- diated responses, and intracellular calcium sequestration. Most biological effects of fatty acids, esters, and phospholipids are transmitted via the interaction of these lipid molecules with specific lipid binding proteins. The chapters in Part II detail the involvement of these in the transport of fatty acids, fatty acyl CoA esters, and phospholipids, and in the proteins modulation of the fatty acid-induced activation of the peroxisome proliferator-activated receptors. The study of arachidonic acid metabolism continues to be the subject of intense interest and research. A number of studies in Part III deal with the substantial differences between the constitutive prostaglandin H synthase isozyme (PGHS-l or COX-I) and the inducible form PGHS-2 (COX-2) regarding compartmentation, control, and expression.

This volume presents a body of research conducted over more than thirty years, including an intensive interdisciplinary five-year study begun in 1991. Chapters include studies of the relationships of biogeography and climate to the region's air pollution, the chemical and physiological mechanisms of ozone injury, as well as the impacts of nitrogen-containing pollutants and natural stresses on polluted forests.

This is an extended version of lectures that were held at the summer workshop Atmosphiirische Umweltforschung im Spannungsfeld zwischen Technik und Natur (At mospheric Environmental Research between Technology and Nature) at the Techni 16, 1996. We were very happy to have Paul J. Crutzen, cal University in Cottbus on July winner of the Nobel Prize for chemistry in 1995, presenting the key lecture on glo bally changing chemistry in the atmosphere. Over the last decades, atmospheric chem istry has been established step by step, not just as an applied discipline of chemistry, but also as a key discipline for our understanding of air pollution, biogeochemical cycling, and climactic processes as well. In fact, the new definition of meteorology as the science of physics and chemistry of the atmosphere expresses this development very well. The chemistry of the atmosphere is strongly influenced by anthropogenic emissions, even on a global scale. As a result of emissions and chemical reactions, the chemical composition of the atmosphere influences the ecosystems directly via depo sition of trace substances, and indirectly by changing the physical climate. Therefore, in this book we combined state-of-the-art lectures describing the physical and chemi cal status of the atmosphere and selected issues representing the interface between atmosphere, technology and nature. Oxidising capacity, heterogeneous processes and acidity still remain as key issues in atmospheric chemistry, even in regions where efficient air control measures have been adopted resulting in reduction of primary atmospheric pollutants."

Biological nitrogen fixation (BNF) - the conversion of molecular nitrogen into ammonia - is one of the most important reactions in ecology and agriculture. It is performed exclusively by microbes (prokaryotes) that live in symbiosis with plants. This book summarizes the latest research on this reaction, the participating microbes and the genetics of how their relevant genes could be transferred into the plants. In the light of a more sustainable and less ecologically damaging agriculture, this is becoming an increasingly pressing issue.

Salinization of soils is a major threat to irrigated agriculture and counteracts the targets of costly public infrastructure investments. In this study, salinization is regarded as the outcome of an institutional arrangement which impedes the effective implementation of well-known and well-established control measures be they technical, managerial or economic. In public irrigation systems neither the management units nor the farmers are offered any incentives towards the control of high groundwater levels and salinization if the management units are embedded in a highly centralized non-market institutional setting. The author answers the question under which conditions management units and irrigators are active in halting and reversing the process of salinization.

Since 1993 a major research programme, "Stochastic Decision Analysis in Forest Management" has been running at Department of Economics and Natural Resources, The Royal Veterinary and Agricultural University (KVL), Copenhagen, in collaboration with Institute of Mathematical Statistics, University of Copenhagen (KU). The research is funded by the two Universities; The Danish Agricultural and Veterinary Research Council; The Danish Research Academy; The National Forest and Nature Agency; and Danish Informatics Network in the Agricultural Sciepces (DINA). A first international workshop in the research programme was held 5 - 8 August, 1996 at Eldrupgaard, Denmark, within the frameworkofacollaborationagreementbetween University of California at Berkeley (UCB) and the Danish Universities, and funded by The Danish Research Academy and the L0venholm Foundation. Having participated in the workshop, Professor Peter Berck (UCB) suggested that the papers be published along with selected papers in the same scientific field, i.e. mainly cointegration analysis of time series in forestry. The editors express their sincere appreciations to the many persons who have contributed to the realisation of the present book: participants in the research programme and the workshop, in particular Professors S0ren Johansen (KU) and Peter Berck (UCB); authors outside the programme/workshop; reviewers of the papers not previously published, in particuler Associate Professors Niels Haldrup (Aarhus University) and Henrik Hansen (KVL); and finally Mrs Mette Riis and Lizzie Rohde who did the tedious work of giving the papers a uniform style. Copenhagen, October 1998.

Fantasies and dreams have their rightful place in science, and sometimes they turn into reality. Regeneration of hybrid plants through protoplast fusion is one such dream come true. In the early 1970s I shared the pioneering excitement in the field of protoplast technology at the Second International Congress of Plant Tissue Culture held in Strasbourg, France. Subsequently, I participated in three international conferences devoted to plant protoplasts, in Salamanca, Spain (1972), Versailles, France (1972), and Nottingham, England (1975). At Versailles Dr. P.S. Carlson presented his work on the successful regeneration of somatic hybrids between Nicotiana glauca and Nicotiana langsdorfii. The enthusi- asm shown by the participants was sufficient indication of the bright future of somatic hybridization. On my return from Versailles, I gathered my thoughts and prepared a concept paper on Potentials of Protoplast Culture Work in Agriculture which was published in Euphytica (Bajaj 1974). The studies on protoplast fusion and somatic hybridization then gained momentum and active work started in many laboratories. Very significant work was done by Melchers et al. (1978) who obtained a somatic hybrid between potato and tomato, calling it "Pomato".

etween 1772 and 1799, Dominique Chaix wrote 170 letters to Dominique Villars. B None of the letters that Vtllars wrote in response have survived, and there is evidence to indicate that Chaix simply did not retain incoming letters once they had served their informative purpose. Villars, blessed with more ample facilities, kept incoming letters; and those from Chaix are now preserved in the Bibliotheque Municipale de Grenoble in three volumes under the number RI0073. A transcription of them for public use was made earlier in this century under the supervision of Georges de Manteyer [Georges-Barthelemy-Marie Pinet de Manteyer] when he was archivist of the Department of Hautes-Alpes. I am gready indebted to Mme Marie-Fran~ise Bois-Delatte, Conservateur des Fonds Dauphinoise at the Bibliotheque Municipale d'Etude et d'lnformation in Grenoble, not merely for making these letters available to me, but for her eagerness to see someone take an interest in Dauphinois botanists. I met a similar friendly interest at the Archives du Departement des Hautes-Alpes in Gap. I thank M. Pierre-Yves Playoust, Directeur des Services, and members of his archival staff for the cordial assistance in my search for materials documenting the career of the abbe Chaix. I am also obligated to the Hunt Institute for Botanical Documentation at Carnegie Mellon University in Pittsburgh for providing me photocopies of Villars' letters in their Allioni collection. They relate to the composition of a flora for Dauphine and are revealing of Villars' character.

This book contains the majority of the presentations of the Second International Symposium on the Biology of Root Formation and Development that was hcld in Jerusa lem, Israel, June 23---28, 1996. Following the First Symposium on the Biology of Adventi tious Root Formation, held in Dallas. USA, 1993, we perceived the need to include all kinds of roots, not only the shoot-borne ones. The endogenous signals that control root formation. and the subsequent growth and development processes, are very much alike, re gardless of the sites and sources of origin of the roots. Therefore, we included in the Sec ond Symposium contributions on both shoot-borne (i.e., adventitious) roots and root-borne (i.e., lateral) roots. Plant roots have remained an exciting and an intriguing field of sciencc. During thc years that followed the first symposium, an exceptional proliferation of interest in root biology has developed, associated with the intensive research activity in this field and the contemporary developments in the understanding of root function and development. New methods have been applied, and old ideas and interprctations werc rccxamined. Alto gether, it became necessary to update our viewpoints and to expand them.

Like the previous nine volumes published between 1988 and 1996, "Medicinal" "and" "Aromatic" "Plants X" is unique in its approach. It comprises 22 chapters dealing with the distribution, importance, conventional propagation, micropropagation, tissue culture studies, and the in vitro production of important medicinal and pharmaceutical compounds in various species of "Actinidia," "Alkanna," "Arnebia," "Campanula," "Catharanthus," "Centella," "Chenopodium," "Cornus," "Cynara," "Ephedra," "Euglena," "Haplophyllum," "Morus," "Oenothera," "Otacanthus," "Oxalis," "Polypodium," "Rosmarinus," "Sesamum," "Solanum," "Taxus," and "Tephrosia." This book is tailored to the needs of advanced students, teachers, and research scientists in the field of pharmacy, plant tissue culture, phytochemistry, biochemical engineering and plant biotechnology.

This proceedings is based on a joint meeting of the two IUFRO (International Union of Forestry Research Organizations) Working Parties, Somatic Cell Genetics (S2.04-07) and Molecular Genetics (S2.04-06) held in Gent, Belgium, 26-30 September, 1995. Although a joint meeting of the two Working Parties had been discussed in the past, this was the first such meeting that became a successful reality. In fact this meeting provided an excellent forum for discussions and interactions in forest bioteclUlology that encouraged the participants to vote for a next joint meeting. In the past decade rapid progress has been made in the somatic cell genetics and molecular genetics of forest trees. In order to cover recent developments in the broad area of biotechnology, the scientific program of the meeting was divided into several sessions. These included somatic embryogenesis, regeneration, transformation, gene expression, molecular markers, genome mapping, and biotic and abiotic stresses. The regeneration of plants, produced by organogenesis or somatic embryogenesis, is necessary not only for mass cloning of forest trees, but also for its application in genetic transformation and molecular biology. Although micropropagation has been achieved from juvenile tissues in a number of forest tree species, in vitro regeneration from mature trees remains a challenging problem in most hardwoods and conifers. The mechanisms involved in the transition from juvenile to mature phase in woody plants are poorly understood. This transition can now be investigated at the molecular level.

Morphometrical differentiation 63 Prediction of breeding origin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68 Body mass 69 Primary moult 69 Discussion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 The taxonomy of the Eurasian Golden Plover 69 The existence of a partial breast-feather moult during breeding 69 Morphometrical differentiation between both sexes . . . . . . . . . . . . . . . . . . . . . . . . 70 The occurrence of primary moult on the breeding grounds 70 Summary 70 6 Grey Plover - Pluvialis squatarola 71 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 Morphometrical differentiation 77 Prediction of breeding origin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 Accuracy 81 Exclusivity 81 Contact zones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82 Body mass 85 Primary moult 85 Discussion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86 The taxonomy of the Grey Plover . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86 Small size at northern latitudes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 Morphometrical variation in the Palearctic 87 Summary 87 7 Red Knot - Calidris canutus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 Morphometrical differentiation 93 Prediction of breeding origin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99 Accuracy 99 Exclusivity 101 Contact zones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102 Body mass 102 Primary moult 103 Discussion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 of the Knot . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 The taxonomy Is the knot breeding in Yakutia? 106 Different degrees of geographical variation in the d'd' and !f!f 106 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107 8 Sanderling - Calidris alba 109 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111 Morphometrical differentiation 111 Prediction of breeding origin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116 Accuracy 116 Exclusivity 118 Contact zones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118 Body mass 118 Primary moult 118 Discussion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118 The taxonomy of the Sanderling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118 Sexing Sanderlings 119 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 VI 9 Curlew Sandpiper - Calidris ferruginea 121 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123 Morphometrical differentiation 123 Prediction of a bird's sex . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127 Accuracy 127 Exclusivity 127 Body mass 127 Primary moult 127 Discussion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127 The taxonomy of the Curlew Sandpiper 127 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

r-------------{ Environment (Disease) Fig. 1. A schematic presentation of the interplay between the external environment, pathogen and animal, which influences resistance to infectious disease. Disturbance in equilibrium results in infection and disease skin and the mucous membranes of the respiratory tract. These tissues are in contact with the environment, and direct injury to them facilitate entry of pathogenic microorganisms through these important natural barriers. Sunburn and frostbite are examples of such adverse effects. Climatic factors such as heat and cold may also act as physiological stress factors which affect the specific and non-specific responses of the body to infection. 1.1.2 Pathogen Survival Climatic factors may affect dispersal, spread and survival of pathogenic micro organisms in the environment. This is also true for arthropod vectors such as mosquitos and ticks (Smith 1970; Ferguson and Branagan 1972). The density of the animal population is an important factor determining the concentration of patho gens in the environment. Population density can be influenced by weather condi tions, as animals respond to heat and cold by typical changes in behaviour. For example, in cold weather they tend to huddle together. This behaviour results in increased population density, which in turn involves an increased risk of the spread of airborne infections."

On the understanding that few people ever read the preface to any book and also on the understanding that even those few people who do read the preface realize that virtually nothing of any substance is ever said, I shall write at such length as will be proportional to my expected readership. The meetings of the International Society on Oxygen Transport to Tissue provide a forum for discussion amongst scientists who, although being from very diverse and specialized backgrounds, have tissue oxygenation as a unifying theme of interest. The wide variety of research material presented in this volume and the multiplicity of the experimental techniques described, should serve as an adequate gauge to the range of expertise and knowledge of the society's members. Such diversity should also stress the importance of the need for multidisciplinary approaches to complex biological problems. In attempting a fundamental characterization of a biological process such as tissue oxygenation, the application of very many separate research skills are necessary, such as mathematics, engi neering, biophysics, biochemistry, physiology, histology and clini cal medicine. The success of the ISOTT has - and we hope - will con tinue to be causing a combination of individuals to direct their specialized knowledge to the many facets of a single proces- tissue oxygenation."