The Microbiology of Nuclear Waste Disposal is a state-of-the-art reference featuring contributions focusing on the impact of microbes on the safe long-term disposal of nuclear waste. This book is the first to cover this important emerging topic, and is written for a wide audience encompassing regulators, implementers, academics, and other stakeholders. The book is also of interest to those working on the wider exploitation of the subsurface, such as bioremediation, carbon capture and storage, geothermal energy, and water quality. Planning for suitable facilities in the U.S., Europe, and Asia has been based mainly on knowledge from the geological and physical sciences. However, recent studies have shown that microbial life can proliferate in the inhospitable environments associated with radioactive waste disposal, and can control the long-term fate of nuclear materials. This can have beneficial and damaging impacts, which need to be quantified.

Suitable for both concept- and context-led approaches, this Revision Guide is Edexcel's own resource for the 2008 Edexcel GCE Chemistry specification. Written by experienced examiners, it features guidance from the people who write and mark exam papers and draws on real exam data from Edexcel's ResultsPlus service. 'ResultsPlus' Examiner feedback draws on examiner expertise and real past exam data to help students avoid common pitfalls and build better answers. Exam-style questions - including the multiple-choice style - offer plenty of practice ahead of the exam. Worked examples provide step-by-step guidance on how totackle exam questions. Guidance on Practical Assessment helps students to write better AS visit/case study and practical reports. Thinking tasks, quick questions and checklistsenable students to track their own progress and revise more effectively.

The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-useful regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials.