Enzymes are giant macromolecules which catalyse biochemical reactions. They are remarkable in many ways. Their three-dimensional structures are highly complex, yet they are formed by spontaneous folding of a linear polypeptide chain. Their catalytic properties are far more impressive than synthetic catalysts which operate under more extreme conditions. Each enzyme catalyses a single chemical reaction on a particular chemical substrate with very high enantioselectivity and enantiospecificity at rates which approach "catalytic perfection." Living cells are capable of carrying out a huge repertoire of enzyme-catalysed chemical reactions, some of which have little or no precedent in organic chemistry.

The popular textbook "Introduction to Enzyme and Coenzyme Chemistry "has been thoroughly updated to include information on the most recent advances in our understanding of enzyme action, with additional recent examples from the literature used to illustrate key points. A major new feature is the inclusion of two-colour figures, and the addition of over 40 new figures of the active sites of enzymes discussed in the text, in order to illustrate the interplay between enzyme structure and function.

This new edition provides a concise but comprehensive account from the perspective of organic chemistry, what enzymes are, how they work, and how they catalyse many of the major classes of enzymatic reactions, and will continue to prove invaluable to both undergraduate and postgraduate students of organic, bio-organic and medicinal chemistry, chemical biology, biochemistry and biotechnology.

"General Chemistry for Engineers" is tailored for a one-semester freshman-level college course for students pursuing engineering degrees. The book offers a balance of conciseness, rigor, and depth needed to prepare students for more advanced coursework and careers in various engineering specialties, such as civil, environmental, electrical, computer, mechanical and industrial engineering, in addition to chemical engineering.
This text leads students through the breadth of a typical two-semester sequence in general chemistry. It elucidates the key concepts and skills important for entering engineering students, including problem solving, qualitative and quantitative thinking, and importance of units. Examples are drawn from problems of interest to modern engineers, including alternative energy, advanced materials, and the environment. The book is the result of the author's unique experiences teaching approximately 2,500 freshman in chemistry and upper-level students in chemical and biological engineering, in addition to leading research and development teaching in the medical device and specialty pharmaceutical industries. The author received a variety of teaching awards at Northeastern honoring his work in making an intense, fast-pace course manageable and exciting.
Paul A. DiMilla is an Associate Academic Specialist in Chemistry & Chemical Biology and Chemical Engineering at Northeastern University. He received his B.S. from the Massachusetts Institute of Technology and his Ph.D. from the University of Pennsylvania, both in Chemical Engineering. He was a Postdoctoral Fellow in Chemistry at Harvard University prior to beginning his faculty career in Chemical and Biomedical Engineering at Carnegie Mellon University, where he co-founded Automated Cell, Inc.
Paul was a Visiting Professor of Bioengineering at the Franklin W. Olin College of Engineering and a Visiting Scholar in Biomedical Engineering at Boston University. Additionally, he led R&D teams in the private sector, developing tissue-engineered medical products and drug- generating biodegradable polymers. He received an Early Career Development Award from the NSF, a Searle Scholar Award, and the first Whitaker Young Investigator Award. He is also the inventor on seven issued US patents.

This book provides non-specialists with a basic understanding ofthe underlying concepts of quantum chemistry. It is both a text for second or third-year undergraduates and a reference for researchers who need a quick introduction or refresher. All chemists and many biochemists, materials scientists, engineers, and physicists routinely user spectroscopic measurements and electronic structure computations in their work. The emphasis of Quantum Chemistry on explaining ideas rather than enumerating facts or presenting procedural details makes this an excellent foundation text/reference. The keystone is laid in the first two chapters which deal with molecular symmetry and the postulates of quantum mechanics, respectively. Symmetry is woven through the narrative of the next three chapters dealing with simple models of translational, rotational, and vibrational motion that underlie molecular spectroscopy and statistical thermodynamics. The next two chapters deal with the electronic structure of the hydrogen atom and hydrogen molecule ion, respectively. Having been armed with a basic knowledge of these prototypical systems, the reader is ready to learn, in the next chapter, the fundamental ideas used to deal with the complexities of many-electron atoms and molecules. These somewhat abstract ideas are illustrated with the venerable Huckel model of planar hydrocarbons in the penultimate chapter. The book concludes with an explanation of the bare minimum of technical choices that must be made to do meaningful electronic structure computations using quantum chemistry software packages.

Atomic and molecular structure, quantum mechanics, statistical mechanics, thermodynamics correlated with descriptive chemistry. Problems.

"An excellent text, highly recommended."-Choice.

Provides an understanding of (mostly) enzymatic reactions that are responsible for the function and maintenance of living things This innovative text for non-biochemistry majors includes introductory material at the beginning of each chapter that contextualizes chapter themes in real-life scenarios Online supporting materials with further opportunities for research and investigation Synthesis questions at the end of each chapter that encourage students to make connections between concepts and ideas, as well as develop critical-thinking skills

Nobel laureate Roald Hoffmann's contributions to chemistry are well known. Less well known, however, is that over a career that spans nearly fifty years, Hoffmann has thought and written extensively about a wide variety of other topics, such as chemistry's relationship to philosophy, literature, and the arts, including the nature of chemical reasoning, the role of symbolism and writing in science, and the relationship between art and craft and science. In Roald Hoffmann on the Philosophy, Art, and Science of Chemistry, Jeffrey Kovac and Michael Weisberg bring together twenty-eight of Hoffmann's most important essays. Gathered here are Hoffmann's most philosophically significant and interesting essays and lectures, many of which are not widely accessible. In essays such as "Why Buy That Theory," "Nearly Circular Reasoning," "How Should Chemists Think," "The Metaphor, Unchained," "Art in Science," and "Molecular Beauty," we find the mature reflections of one of America's leading scientists. Organized under the general headings of Chemical Reasoning and Explanation, Writing and Communicating, Art and Science, Education, and Ethics, these stimulating essays provide invaluable insight into the teaching and practice of science.