H4 R is the newest member of the histamine receptor family, which was discovered about twelve years ago. It is considered a very promising drug target. The effort to improve the pharmacokinetic properties of the currently available H4 R ligands is reflected in a steadily growing number of scientific publications and patent applications. Preclinical data strongly confirms the need for novel potent H4 R ligands to explore their therapeutic value in allergy, inflammation, autoimmune disorders, and possibly, cancer. Readers will be provided with extensive knowledge on histamine metabolism, as well as cellular histamine transport, storage and release, effects of histamine and histamine receptor ligands, with particular attention to the H4 R, on inflammatory cells including mast cells, basophils, eosinophils, neutrophils, macrophages, dendritic cells, and T cells. The present knowledge on the regulatory role of histamine and the therapeutic exploitation of histamine receptor ligands in atopic diseases, with emphasis on human and animal models of asthma, allergic dermatitis and pruritus are discussed.

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects - properties, synthesis, reactions, physiological and industrial significance - of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

DFT methods are widely used in a broad range of disciplines to investigate many body systems. This book provides an overview on contemporary applications of the Density Functional Theory in various fields as computational chemistry, physics or engineering.

The "greening" of industry processes - i.e., making them more sustainable - is a popular and often lucrative trend which has seen increased attention in recent years. Green Chemical Processes, the 2nd volume of Green Chemical Processing, covers the hot topic of sustainability in chemistry with a view to education, as well as considering corporate and environmental interests, e.g. in the context of energy production. The diverse team of authors allows for a balance between these different, but interconnected perspectives. The American Chemical Society's 12 Principles of Green Chemistry are woven throughout this text as well as the series to which this book belongs.

This book highlights the evolution of, and novel challenges currently facing, nanomaterials science, nanoengineering, and nanotechnology, and their applications and development in the biological and biomedical fields. It details different nanoscale and nanostructured materials syntheses, processing, characterization, and applications, and considers improvements that can be made in nanostructured materials with their different biomedical applications. The book also briefly covers the state of the art of different nanomaterials design, synthesis, fabrication and their potential biomedical applications. It will be particularly useful for reading and research purposes, especially for science and engineering students, academics, and industrial researchers.

This book investigates in detail the concepts and principles of green chemistry and related methodologies, including green synthesis, green activation methods, green catalysis, green solvents, and green design to achieve process intensification while at the same time ensuring process safety and promoting ecological civilization and environmental protection. Moreover, it incorporates elements of chemical management and chemical education, highlighting chemists' responsibility to protect humankind and foster green and sustainable development in chemistry. Combining Chinese and Belarus wisdom, this book is intended for those working in the chemical industry who are interested in environmental protection and sustainable development, as well as undergraduate and graduate students who are interested in green chemistry and related technologies.

Personal protective equipment (PPE) is critical for those dealing with toxic, infectious, and radioactive materials. An easily accessible guide for professionals and researchers in all PPE fields, this book takes a fresh look at how PPE is designed, selected, and used in today's emergency response environment where users may need to be protected against deliberately used chemical, biological, or radiological agents in terrorism or warfare scenarios as well as more traditional hazards. Covering the physics, chemistry, and physiology of these hazards, the book explains how PPE protects from various forms of hazards as well as how to use this information to select PPE against these highly hazardous substances for first responder or military users. The design of PPE and components plus relevant performance and evaluation standards are also discussed.

This book contains 959 cosmetic and toiletry formulations, based on information received from numerous industrial companies and other organizations. This is Volume 4 of the Second Edition of this work; Volume 1 was published in 1989, Volume 2 in 1992, and Volume 3 in early 1995. There are no duplications in any of these volumes.

The data represent selections from manufacturers' descriptions made at no cost to, nor influence from, the makers or distributors of these materials. Only the most recent formulas have been included. It is believed that all of the trademarked raw materials listed are currently available, which will be of interest to readers concerned with raw material discontinuances.

The cosmetic and toiletry raw materials market is projected to increase to close to $2.0 billion in 1995. The information in this book will be of particular interest to anyone considering new products or process variations. Each formulation in the book is identified by a description of end use. The formulations include the following as available, in the manufacturer's own words: a listing of each raw material contained; the percent by weight of each raw material; suggested formulation procedure; and the formula source, which is the company or organization that supplied the formula.

Each formula is indexed in the section that is most applicable. The reader seeking a formula for a specific end use should check each section, which could possibly apply.

The formulations in the book are divided into twelve categories as shown below. In addition, a valuable section on Trade-Named Raw Materials is included, which lists trade names, a brief chemical description, and the supplier's name. Thefinal section contains Suppliers' Addresses and will no doubt be a useful tool to the reader.

Section titles are listed below. Parenthetic numbers indicate the number of formulations per topic.

Sustainable Green Chemistry, the 1st volume of Green Chemical Processing, covers several key aspects of modern green processing. The scope of this volume goes beyond bio- and organic chemistry, highlighting the ecological and economic benefits of enhanced sustainability in such diverse fields as petrochemistry, metal production and wastewater treatment. The authors discuss recent progresses and challenges in the implementation of green chemical processes as well as their transfer from academia to industry and teaching at all levels. Selected successes in the greening of established processes and reactions are presented, including the use of switchable polarity solvents, actinide recovery using ionic liquids, and the removal of the ubiquitous bisphenol A molecule from effluent streams by phytodegradation.

How can students, teachers, parents, and librarians be certain that the information a Web site provides is accurate and age appropriate? In this unique book, experienced science educator Judith A. Bazler reviews hundreds of the most reliable chemistry-related Web sites. Each review discusses the most appropriate grade level of the site, analyzes its accuracy and usefulness, and provides helpful hints for getting the most out of the resource. The Web is the first place many students look for information. Yet the Web is notoriously unreliable. How can students, teachers, parents, and librarians be certain that the information a Web site provides is accurate and age appropriate? In this unique book, experienced science educator Judith A. Bazler reviews hundreds of the most reliable chemistry-related Web sites. Each review discusses the most appropriate grade level of the site, analyzes its accuracy and usefulness, and provides helpful hints for getting the most out of the resource. Sites are organized by topic, from Acids to Thermodynamics, making it easy to locate the most useful sites. A handy summary presents the best places on the Web to find information on science museums, science centers, careers in chemistry, and chemistry supplies.

This book comprises a collection of chapters on advances in green nanomaterials. The book looks at ways to establish long-term safe and sustainable forms of nanotechnology through implementation of nanoparticle biosynthesis with minimum impact on the ecosystem. The book looks at synthesis, processing, and applications of metal and metal oxide nanomaterials and also at bio-nanomaterials. The contents of this book will prove useful for researchers and professionals working in the field of nanomaterials and green technology.

Cellulose nanocrystals are being used more frequently as processing and nanofabrication techniques have advanced considerably. Cellulose Nanocrystals includes topics including Extraction and Fabrication Methodologies, Scale-Up Strategies and Life Cycle Assessment, Surface Modification Strategies, Nanocomposites, and Characterization and Testing Protocols. This book will appeal to physical, chemical and biological scientists as well as engineers.

The definitive guide to creating fluorine-based compounds and the materials of tomorrow Discovered as an element by the French chemist Henri Moissan in 1886, through electrolysis of potassium fluoride in anhydrous hydrogen fluoride "le fluor," or fluorine, began its chemical history as a substance both elusive and dangerous. With a slight pale yellow hue, fluorine is at room temperature a poisonous diatomic gas. Resembling a spirit from a chemical netherworld, fluorine is highly reactive, difficult to handle, yet very versatile as a reagent with the power to form compounds with almost any other element. Comprising 20% of pharmaceutical products and 30% of agrochemical compounds, as well as playing a key role in electric cars, electronic devices, and space technology, compounds containing fluorine have grown in importance across the globe. Learning how to safely handle fluorine in the preparation of innovative new materials with valuable new properties is of critical importance to chemists today. Bringing together the research and methods of leading scientists in the fluorine field, Efficient Preparations of Fluorine Compounds is the definitive manual to creating, and understanding the reaction mechanisms integral to a wide variety of fluorine compounds. With sixty-eight contributed chapters, the book's extensive coverage includes: * Preparation of Elemental Fluorine * Synthesis Methods for Exotic Inorganic Fluorides with Varied Applications * Introduction of Fluorine into Compounds via Electrophilic and Nucleophilic Reactions * Direct Fluorination of Organic Compounds with Elemental Fluorine * Efficient Preparations of Bioorganic Fluorine Compounds * Asymmetric Fluorocyclization Reactions * Preparations of Rare Earth Fluorosulfides and Oxyfluorosulfides The book offers methods and results that can be reproduced by students involved in advanced studies, as well as practicing chemists, pharmaceutical scientists, biologists, and environmental researchers. The only chemical resource of its kind, Efficient Preparations of Fluorine Compounds from its first experiment to its last is a unique window into the centuries old science of fluorine and the limitless universe of fluorine-based compounds.

Organic Chemistry has been designed to meet the needs of the two-semester, undergraduate organic chemistry course. This best-selling text gives students a solid understanding of organic chemistry by focusing on how fundamental reaction mechanisms function and reactions occur. The authors strive for students to have a deeper understanding of the physical concepts that underlie organic chemistry, and for them to have a broader knowledge of the role of organic chemistry in biological systems. The text is strengthened by its offering in ALEKS, now featuring Custom Question Authoring, Video Assignments, Virtual Labs, and more!

Supercritical fluids behave either like a gas or a liquid, depending on the values of thermodynamic properties. This tuning of properties, and other advantageous properties of supercritical fluids led to innovative technologies. More than 100 plants of production size are now in operation worldwide in the areas of process and production technology, environmental applications, and particle engineering. New processes are under research and development in various fields.

This book provides an overview of the research activities in the field of Supercritical Fluids in Germany. It is based on the research program "Supercritical fluids as solvents and reaction media" on the initiative of the "GVC-Fachausschu Hochdruckverfahrenstechnik" (i.e. the German working party on High Pressure Chemical Engineering of the Society of Chemical Engineers).

This research program provided an immensely valuable platform for exchange of knowledge and experience. More than 50 young researchers were involved contributing with their expertise, their new ideas, and the motivation of youth. The results of this innovative research are described in this book.
- This book provides an overview of the research activities in the field of Supercritical Fluids in Germany
- Contains results of projects within the research program on "Supercritical fluids as solvents and reaction media" on the initiative of the German working party on High Pressure Chemical Engineering of the Society of Chemical Engineers.
- More than 50 young researchers were involved in contributing with their expertise, their new ideas, and the motivation of youth.

Revise smart and save! Designed for hassle-free classroom and independent study, our Revision Guides are designed to complement the Student Books with a range of specially designed features such as: One-topic-per-page format Worked examples with exemplar answers 'Now Try This' practice questions Knowledge checks and skills checks Includes FREE online edition! With a one-to-one page correspondence between this Revision Guide and the companion OCR AS/A level Chemistry Revision Workbook, the hugely popular REVISE series offers the best value available for A level students.

This book demonstrates the basic and fundamental aspects of nanotechnology and potential application as a photocatalysis in multiple application especially in environment and energy harvesting. This book also contains methods of preparation and characterization of unique nanostructured photocatalysts, and details about their catalytic action. The book consists of seven chapters, including the principles and fundamentals of heterogeneous photocatalysis; the mechanisms and dynamics of surface photocatalysis; research on pure and composites based materials with unique nanostructures; the latest developments and advances in exploiting photocatalyst alternatives to WO3; and photocatalytic materials for applications other than the traditional degradation of pollutants, such as carbon dioxide reduction, water oxidation, a complete spectrum of selective organic transformations and water splitting by photocatalytic reduction. This book will appeal to a wide readership of the academic and industrial researchers and it can also be used in the classroom for undergraduate and graduate students focusing on heterogeneous photocatalysis, sustainable chemistry, energy conversion and storage, nanotechnology, chemical engineering, environmental protection, optoelectronics, sensors, and surface and interface science.