Compound Histories: Materials, Governance and Production, 1760-1840 offers a new view of the period during which Europe took on its modern character and globally dominant position. By exploring the intertwined realms of production, governance and materials, it places chemists and chemistry at the center of processes most closely identified with the construction of the modern world. This includes the interactive intensification of material and knowledge production; the growth and management of consumption; environmental changes, regulation of materials, markets, landscapes and societies; and practices embodied in political economy. Rather than emphasize revolutionary breaks and the primacy of innovation-driven change, the volume highlights the continuities and accumulation of incremental changes that framed historical development. Contributors are: Robert G.W. Anderson, Bernadette Bensaude Vincent, Jose Ramon Bertomeu Sanchez, John R.R. Christie, Joppe van Driel, Frank A.J.L. James, Christine Lehman, Lissa L. Roberts, Thomas le Roux, Elena Serrano, Anna Simmons, Marie Thebaud-Sorger, Sacha Tomic, Andreas Weber, Simon Werrett.

As a byproduct of historical development, there are different, unrelated systems of nomenclature for "inorganic chemistry," "organic chemistry," "polymer chemistry," "natural products chemistry," etc. With each new discovery in the laboratory, as well as each new theoretical proposal for a chemical, the lines that traditionally have separated these "distinct" subsets of matter continually grow more blurred. This lack of uniformity in characterizing and naming chemicals increases the communication difficulties between differently trained chemists, as well as other scientists, and greatly impedes progress. With the set of known chemicals numbering over 42,000,000 (in Chemical Abstracts' data base) and continually growing (about 2,000 new additions every day), the desirability for a unified system for naming all chemicals simultaneously grows. Moreover, in order to meet the requirements of disparate groups of scientists, and of society in general, the name assigned to a given chemical should, not only uniquely describe that substance, but also should be a part of a readily recognizable order for the entire field. For these purposes, a topology-based "bi-parametric" system of nomenclature is herein proposed.
- In this book, a new nomenclature system is proposed
- The new nomenclature is applicable to a three dimensional world, and is internally consistent
- This nomenclature unifies ALL branches of chemistry, removing the need for various presently existing sets of rules

Clinical research is heavily regulated and involves coordination of numerous pharmaceutical-related disciplines. Each individual trial involves contractual, regulatory, and ethics approval at each site and in each country. Clinical trials have become so complex and government requirements so stringent that researchers often approach trials too cautiously, convinced that the process is bound to be insurmountably complicated and riddled with roadblocks. A step back is needed, an objective examination of the drug development process as a whole, and recommendations made for streamlining the process at all stages. With Intelligent Drug Development, Michael Tansey systematically addresses the key elements that affect the quality, timeliness, and cost-effectiveness of the drug-development process, and identifies steps that can be adjusted and made more efficient. Tansey uses his own experiences conducting clinical trials to create a guide that provides flexible, adaptable ways of implementing the necessary processes of development. Moreover, the processes described in the book are not dependent either on a particular company structure or on any specific technology; thus, Tansey's approach can be implemented at any company, regardless of size. The book includes specific examples that illustrate some of the ways in which the principles can be applied, as well as suggestions for providing a better context in which the changes can be implemented. The protocols for drug development and clinical research have grown increasingly complex in recent years, making Intelligent Drug Development a needed examination of the pharmaceutical process.

This book is a "world first," since the furfural industry has been traditionally secretive to the point of appearing shrouded in clouds of mystery. Even renowned encyclopedic works have published but scant and often erroneous information on the subject.
Striking a healthy balance between theory and practice, the book leads the reader from reaction mechanisms and kinetics to the technology of making furfural by various old and new processes, using conventional raw materials or sulfite waste liquor. Detailed discussions of means of increasing the yield are of great chemical and technological interest as well as of immense economic importance.
From furfural proper, the treatise shifts to the fascinating field of wanted and unwanted by-products ranging from largely unutilized carboxylic acids to troublesome impurities such as 5-methyl furfural and 2-furyl methyl ketone, and then to extremely valuable serendipitous flavor compounds such as diacetyl and 2,3-pentanedione. A wide variety of derivatives are discussed; considerable space is devoted to polytetrahydrofuran, an important building block of stretchable synthetic fibers, while furan resins from both furfural and furfuryl alcohol are given the attention commensurate with their industrial importance.
Notable supplementary chapters cover the in-line measurement of furfural, the treatment of furfural waste water, and various aspects of corrosion. A chapter on the applications of furfural elaborates not only traditional uses in extracting petroleum and vegetable oils but also the sensational discovery that furfural is a highly effective "indirect nematocide." Without becoming toxic, it changes the microflora of the soil by stimulating bacteria antagonistic to nematodes, thereby reducing the nematode population to zero, at an unprecedented low price. It is believed that this application will be the principal outlet for furfural in the future.
A comprehensive list of physical properties, some never published before, make the book an indispensable companion for producers, users and researchers alike.

People in poverty suffer daily under misconceptions about economic hardship and its causes. Providing the most comprehensive consideration to date of poverty in the United States, Elizabeth Seale tackles how we think about issues of culture, behavior, and poverty, cutting straight to the heart of debates about social class. The book addresses tough questions, including how being poor affects individual behavior, and how we can make sense of that in a larger social and political context. The central premise is that to understand the behavior and lives of people in poverty, one must consider their relational context, especially relations of vulnerability and the human need for dignity. Poverty is a social problem we should address as a society by changing social relations that, as a matter of course, cause unnecessary and immense suffering. To do so, we must directly confront our lack of regard for people in poverty by recognizing that they are in fact worthy of an effort to induce major social change. This critical introduction to poverty will be an important read for undergraduate students and above in sociology wanting to learn more about the growing social problems of poverty, inequality, and stratification.

This book contains 652 cosmetic and toiletry formulations, based on information received from numerous industrial companies and other organizations. This is volume 6 of the Second Edition of this work; Volume 1 was published in 1989, Volume 2 in 1992, Volume 3 in early 1995, Volume 4 in late 1995, and Volume 5 in 1996. There are no duplications in any of these volumes. Each formulation in the book is identified by a description and an end use. The formulations include as available: a listing of each raw material contained; the percentage by weight of each raw material; suggested formulation procedure; formula source.

The QuickStudy Books linecovers the key information on some of the toughest courses today, helping students boost their grades. The books are presented in the clear, concise format readers have come to expect from QuickStudy.
Chemistry essentials for all students, including laboratory basics.
Easy-to-use reference for concepts designed specifically to aid science students.
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Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals

This book reviews the advances and challenges of structure-based drug design in the preclinical drug discovery process, addressing various diseases, including malaria, tuberculosis and cancer. Written by internationally recognized researchers, this edited book discusses how the application of the various in-silico techniques, such as molecular docking, virtual screening, pharmacophore modeling, molecular dynamics simulations, and residue interaction networks offers insights into pharmacologically active novel molecular entities. It presents a clear concept of the molecular mechanism of different drug targets and explores methods to help understand drug resistance. In addition, it includes chapters dedicated to natural-product- derived medicines, combinatorial drug discovery, the CryoEM technique for structure-based drug design and big data in drug discovery. The book offers an invaluable resource for graduate and postgraduate students, as well as for researchers in academic and industrial laboratories working in the areas of chemoinformatics, medicinal and pharmaceutical chemistry and pharmacoinformatics.

Advances in Clinical Chemistry, Volume 82, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. This updated volume includes chapters on Calcium and Bone Metabolism Indices, Cytokines and MicroRNA in Coronary Artery Disease, Biological and molecular characterization of circulating tumor cells: A creative strategy for precision medicine?, Towards a blood-borne biomarker of chronic hypoxemia: Red cell distribution width and respiratory disease, miRNAs: nanomachines that microManage the pathophysiology of Diabetes mellitus, and Fortilin, A Potential Target for the Prevention and Treatment of Human Diseases. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

The data represents selections from manufacturers' descriptions made at no cost to, nor influence from, the makers or distributors of these materials. Only the most recent formulas have been included. It is believed that all of the trademarked raw materials listed are currently available, which will be of interest to readers concerned with raw material discontinuances. The 1996 market for cosmetic raw materials is estimated at $2 billion.

Each formulation in the book is identified by a description of end use. The formulations include the following as available, in the manufacturers' own words: a listing of each raw material contained; the percent by weight of each raw material; suggested formulation procedure; and the formula source, which is the company or organization that supplied the formula.

Each formula is indexed in the section which is most applicable. The reader seeking a formula for a specific end use should check each section which could possibly apply. In addition there are two other sections that will be helpful to the reader: Trade-Named Raw Materials where each raw material is listed with a brief chemical description, and the supplier's name. The final section contains Suppliers' Addresses.

It should be noted that some formulations in the book are translations. The manufacturer's exact wording has been used in these cases. Occasionally different companies have listed the same raw material differently; it is hoped that the reader will be able to identify the same or similar raw materials by consulting the Trade-Named Raw Materials section.

Section Titles are listed below. Parenthetic numbers indicate the number of formulations per topic.