The tenth edition of Chemistry: The Molecular Nature of Matter and Change maintains its standard-setting position among general chemistry textbooks by evolving further to meet the needs of professor and student. The text still contains the most accurate molecular illustrations, consistent step-by-step worked problems, and an extensive collection of end-of-chapter problems. And changes throughout this edition make the text more readable and succinct, the artwork more teachable and modern, and the design more focused and inviting. The three hallmarks that have made this text a market leader are now demonstrated in its pages more clearly than ever. The text is strengthened by its offering in ALEKS, now featuring Custom Question Authoring, Video Assignments, Virtual Labs, and more!

GENOME EDITING IN DRUG DISCOVERY A practical guide for researchers and professionals applying genome editing techniques to drug discovery In Genome Editing in Drug Discovery, a team of distinguished biologists delivers a comprehensive exploration of genome editing in the drug discovery process, with coverage of the technology's history, current issues and techniques, and future perspectives and research directions. The book discusses techniques for disease modeling, target identification with CRISPR, safety studies, therapeutic editing, and intellectual property issues. The safety and efficacy of drugs and new target discovery, as well as next-generation therapeutics are also presented. Offering practical suggestions for practitioners and academicians involved in drug discovery, Genome Editing in Drug Discovery is a fulsome treatment of a technology that has become part of nearly every early step in the drug discovery pipeline. Selected contributions also include: A thorough introduction to the applications of CRISPRi and CRISPRa in drug discovery Comprehensive explorations of genome-editing applications in stem cell engineering and regenerative medicine Practical discussions of the safety aspects of genome editing with respect to immunogenicity and the specificity of CRISPR-Cas9 gene editing In-depth examinations of critical socio-economic and bioethical challenges in the CRISPR-Cas9 patent landscape Perfect for academic researchers and professionals in the biotech and pharmaceutical industries, Genome Editing in Drug Discovery will also earn a place in the libraries of medicinal chemists, biochemists, and molecular biologists.

Investigation techniques and analytical methodologies for addressing microbial contamination indoors

Microbial contamination indoors is a significant environmental and occupational health and safety problem. This book provides fundamental background information on fungal and bacterial growth indoors as well as in-depth, practical approaches to analyzing and remedying problems. The information helps investigators, laboratory managers, and environmental health professionals properly use state-of-the-science methods and correctly interpret the results. With chapters by expert microbiologists, mycologists, environmental professionals, and industrial hygienists, Sampling and Analysis of Indoor Microorganisms is a multidisciplinary, comprehensive reference on advanced approaches, covering: Microbiological problems in a water-damaged environment Indoor construction techniques and materials that impact environmental microbiology Microbial ecology indoors, airborne bacteria, genetic-based analytical methods, and statistical tools for microorganism analysis Microbiological sampling approaches Mold removal principles and methods, including specialized microbial remediation techniques for HVAC systems, legionellas and biofilms, and sewage contamination A forensic approach toward the assessment of fungal growth in the indoor environment

A must-have guide for practicing professionals, including environmental health and safety personnel, public health officials, and building and construction engineers and architects, this is also a valuable reference for attorneys, home inspectors, water restoration personnel, mold remediation contractors, insurance adjusters, and others.

From cooking to medicine, from engineering to art, chemistry-the science of molecules-is everywhere. A celebration of the molecules of chemistry, Every Molecule Tells a Story celebrates the molecules responsible for the experiences of everyday life: the air we breathe; the water we drink; the chemicals that fuel our living; the steroids that give us sex; the colours of the seasons; the drugs that heal us; and the scented molecules that enrich our diet and our encounters with each other. You can't see them, but you know that they are there. Unveiling the structures of poisonous "natural" substances and beneficial man-made molecules, this book brushes away any preconceived notions about chemistry to demonstrate why and how molecules matter.

A HANDS-ON MANUAL FOR THE SAFETY AND DESIGN OF COMPLEX PROCESS VENTING SYSTEMS

Process vent header collection systems are subject to continually varying compositions and flow rates and thus present significant challenges for safe design. Due to increasingly demanding safety, health, environmental, and property protection requirements, today's industrial designers are faced with the need

to create increasingly complex systems for more effective treatment, dispersal, or disposal of process gases.

Safe Design and Operation of Process Vents and Emission Control Systems provides cutting-edgeguidance for the design, evaluation, and operation of these systems, with emphasis on: Preventing fires, explosions, and toxic releases Maintaining safe vent conditions Understanding normal process operations, such as intentional routine controlled venting and emergency operations, like overpressure relief Mitigating the impacts of end-of-line treatment devices, such as scrubbers, flares, and thermal oxidizers, on the vent header system Complying with regulations

Written by a team of process safety experts from the chemical, pharmaceutical, and petroleum industries, the book includes a wealth of real-world examples and a thorough overview of the tools and methods used in the profession.

Since 1987, the Petroleum Division of the American Chemical Society (ACS) has sponsored at 3 year intervals an international symposium on fluid cracking catalysts (FCC) technology. This volume collects the recent progress of this technology as reported in the papers presented during the 232th National Meeting of the ACS in San Francisco, September 10-14, 2006.
Sixty-six years after the introduction of the fluid cracking catalyst process, it remains the main process of gasoline generation for the estimated 237 millions cars on US roads. Catalysts testing and evaluation still remains a subject of interest, debate and controversy. Lambda sweep testing, testing of SOx, NOx and combustion promoters have been discussed in details together with catalyst evaluation for atmospheric residues and metal contaminated oils cracking.
Of particular interest has been the introduction of novel concept in process design aimed at improving cracked product selectivity such as two-stage risers for better gasoline and olefins production and downer technology for high severity processes . The importance of solid state nuclear magnetic resonance (NMR) in the study of crude oils, catalysts and reaction products are illustrated by several examples. Two contributions describe the use of predictive methods to understand FCC aging and deactivation
and personal overviews of the development of SOx and combustion promoters technology are presented.
* Presents findings from the tri-annual international symposium on fluid cracking catalysts (FCC) technology, sponsored by the Petroleum Division of the American Chemical Society (ACS)
* Two contributions describe the use of predictive methods to understand FCC aging and deactivation
* Personal overviews by the authors of the development of SOx and combustion promoters technology

Metal-Sulfur clusters play an essential role in living organisms through the unique character of sulfur-metal bonding. The new volume in prestigious Metal Ions in Life Sciences explores different transition metal complexes with sulfur, their biosynthesis and biological functions in regulation of gene expression, catalysis of important metabolic reactions and protein structure arrangement.

The declining supply of crude oils worldwide and the ever increasing demand for petroleum products from China, India, Europe and the US have recently propelled crude prices to unprecedented levels. The future availability of traditional crudes is becoming a source of discussion and debate.
Fischer-Tropsch Synthesis, Catalysts and Catalysis offers a timely and comprehensive report on the processing of relatively inexpensive coal deposits into transportation fluids using Fisher-Tropsch process Technology. In addition to recent catalysts and process developments, the book contains the history of the Fisher-Tropsch in Germany and Japan based on captured documents by allied forces.
* Increase the understanding of FT process development
* Addresses four major areas of interest in Fischer-Tropsch synthesis (FTS)

Inorganic Pollutants in Water provides a clear understanding of inorganic pollutants and the challenges they cause in aquatic environments. The book explores the point of source, how they enter water, the effects they have, and their eventual detection and removal. Through a series of case studies, the authors explore the success of the detection and removal techniques they have developed. Users will find this to be a single platform of information on inorganic pollutants that is ideal for researchers, engineers and technologists working in the fields of environmental science, environmental engineering and chemical engineering/ sustainability. Through this text, the authors introduce new researchers to the problem of inorganic contaminants in water, while also presenting the current state-of-the-art in terms of research and technologies to tackle this problem.

The 7th International Symposium on the Characterization of Porous Solids (COPS-VII) was held in the Congress Centre in Aix-en-Provence between the 25th-28th May 2005.
The symposium covered recent results of fundamental and applied research on the characterization of porous solids. Papers relating to characterization methods such as gas adsorption and liquid porosimetry, X-ray techniques and microscopic measurements as well as the corresponding molecular modelling methods were given. These characterization methods were shown to be applied to all types of porous solids such as clays, carbons, ordered mesoporous materials, porous glasses, oxides, zeolites and metal organic frameworks.
* 36 oral presentations and 166 posters and around 230 guests from 27 countries.
* A large part of this symposium was devoted to the use computational methods to characterise porous solids

This is the first major review of the developments in clinical laboratory science in the 20th century presented in the words of the original inventors and discoverers. Introductory comments by the editor help place the works within the historical context.
Landmark Papers addresses:
*The origin of the home pregnancy test available today in every drugstore
*The woman who invented a billion dollar technology, refused to patent it and went on to win a Nobel Prize
*The scientists who worked on the US Government's crash program at the start of WWII to find a substitute for the malaria drug quinine
*The blood test used to monitor the effectiveness of cholesterol lowering drugs that today are taken by over 20 million patients
*The graduate student who invented a technology for testing for infectious diseases, took it to Africa to screen people for malaria for the first time and which is now used to test for HIV infection world-wide
*The invention of molecular diagnostics by Linus Pauling and the road to individualized medicine
*The development of the glucose meter used by diabetics up to six times a day to monitor their metabolic control
*First book of this kind dedicated to clinical chemistry
*Thirty-nine articles that have shaped the field today
*A survey of the major developments in the field clinical chemistry in the 20th century

Annual Reports in Computational Chemistry is a new periodical providing timely and critical reviews of important topics in computational chemistry as applied to all chemical disciplines. Topics covered include quantum chemistry, molecular mechanics, force fields, chemical education, and applications in academic and industrial settings. Each volume is organized into (thematic) sections with contributions written by experts. Focusing on the most recent literature and advances in the field, each article covers a specific topic of importance to computational chemists. Annual Reports in Computational Chemistry is a 'must' for researchers and students wishing to stay up-to-date on current developments in computational chemistry.
In Volume 3, topics covered include Simulation Methodologies (Carlos Simmerling), Biological and Biophysical Applications (Heather Carlson), Chemical Education (Theresa Zielinski), Materials and Polymers (Jeffry Madura), Quantum Chemistry (T. Daniel Crawford), and Emerging Technologies (Wendy Cornell). With this volume we extend the practice of cumulative indexing of both the current and past editions in order to provide easy identification of past reports.
* Broad coverage of computational chemistry and up-to-date information
* Topics covered include quantum chemistry, molecular mechanics, force fields, chemical education, and applications in academic and industrial settings
* Each chapter reviews the most recent literature on a specific topic of interest to computational chemists